Protein Alignment Rph and syt7a

DIOPT Version :10

• Sequence 1: NP_572651.1
• Gene: Rph / 32002
• FlyBaseID: FBgn0030230
• Length: 638
• Species: Drosophila melanogaster
• Sequence 2: XP_021326273.2
• Gene: syt7a / 561429
• ZFINID: ZDB-GENE-090601-5
• Length: 653
• Species: Danio rerio
• Alignment Length: 523
• Identity: 138/523 - (26%)
• Similarity: 212/523 - (40%)
• Gaps: 110/523 - (21%)

  Fly   161 DMPRSASATPIPNPGPGSMAGDTRAVQSCHATPTRPARVKKLTIRVNDSSSSSSGHSEPEDEVDT 225
            |...||.|||.|.         |...|.....|...|....|..|...|.|....|::|.
Zfish   187 DYVPSAGATPRPR---------TLLRQQSLQQPLIQAPPPNLASRPPISQSLGQLHTQPG----- 237

  Fly   226 GVGIGVGVVGGGMAKGIASTRLQREDSFRLRAYGS------------------------IRSFID 266
                |.|..|||.    |.:|..|.:..:.|:.|:                        ::||::
Zfish   238 ----GAGPGGGGG----AGSRNSRGEPAQHRSAGAGGRGSGNPGSVDHMMGQIKKRGLDVKSFLE 294

  Fly   267 GGERKLSNSF-------FFN---RQQSQRPSECPEYDSVSMSKLRRESSFLRRGSVSSSWSISDS 321
            |....||.:.       |.|   .|:.....|.|| .|.:|......|...:........|:||.
Zfish   295 GKMVVLSLAIGLAEQDDFANLPDLQEVPASQETPE-KSRNMGNKPANSPKGQPPDADGHSSVSDL 358

  Fly   322 SGSGSNNSGNSQTQSQYQQHQQQLQQHCRDPLLGWLEIAISYREAFHSLDCTMVRARDLPAMDAA 386
            :.|.:.:.......|:...|:..:.:.     ||.::.::.|.....:|...:::.:||||.|.:
Zfish   359 ANSLTGDMVMLSPGSEDDDHEGPVSEK-----LGRIQFSLGYSFQDTTLTVKILKGQDLPAKDFS 418

  Fly   387 GLADPYCKLNIITPEAHTKYTRWQRTKTVHKTRNPEFNETLQFVGVEPEELGNSLIYVALFDDDK 451
            |.:||:.|:.::....|.     ..||...|..||.:|||..|.|...|::....:|:.:.|.|:
Zfish   419 GTSDPFVKIYLLPDRKHK-----LETKVKRKNLNPHWNETFLFEGFPYEKVRERTLYLQVLDYDR 478

  Fly   452 YG-HDFLGAAKVCLSTVHSTSQYRISVPLGVEDQYSNAAEMAQ---NWPN-----------GKML 501
            :. :|.:|               .:|:||       |..|:.|   .|.:           |.:|
Zfish   479 FSRNDPIG---------------EVSIPL-------NKVELGQLKSFWKDLKPCSDGSGSRGDLL 521

  Fly   502 LSLCYNTKRRALVVNVKQCINLMAMDNNGSSDPFVKIQLKPDAHKNK---KHKTSVKWRTLNPIY 563
            :|||||.....:.||:.:..||.|||..|:|||:||:.|   .||:|   |.||....|.|||::
Zfish   522 VSLCYNPTANTITVNIIKARNLKAMDIGGTSDPYVKVWL---MHKDKRVEKKKTVTIKRCLNPVF 583

  Fly   564 NEEFYFEASPHDLNKEMLILTVWDKDLGKSNDFLGSLQLGAQSKGERLQQWLDCIRLPDHFHEKW 628
            ||.|.|:...|.|.:..:|:||.|||....||.:|.:.|..:|....::.|.|.:..|.....:|
Zfish   584 NESFPFDVPAHVLRETTIIITVMDKDRLSRNDVIGKIYLSWKSGPGEVKHWKDMLSRPRTNVAQW 648

  Fly   629 HCL 631
            |.|
Zfish   649 HAL 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rph	NP_572651.1	FYVE_like_SF	84..172	CDD:333710	6/10 (60%)
		C2A_Rabphilin_Doc2	354..477	CDD:176000	30/123 (24%)
		C2B_Rabphilin_Doc2	499..631	CDD:176030	52/134 (39%)
syt7a	XP_021326273.2	None