Protein Alignment Rph and syt2b

DIOPT Version :10

• Sequence 1: NP_572651.1
• Gene: Rph / 32002
• FlyBaseID: FBgn0030230
• Length: 638
• Species: Drosophila melanogaster
• Sequence 2: XP_005166211.1
• Gene: syt2b / 559637
• ZFINID: ZDB-GENE-090717-1
• Length: 436
• Species: Danio rerio
• Alignment Length: 300
• Identity: 96/300 - (32%)
• Similarity: 163/300 - (54%)
• Gaps: 22/300 - (7%)

  Fly   334 TQSQYQQHQQQLQQHCRDPLLGWLEIAISYREAFHSLDCTMVRARDLPAMDAAGLADPYCKLNII 398
            |:.:.::.::::::      ||.|:.::.|....:.|...:::..||.:||:.|.:|||.|: .|
Zfish   140 TEEEKEEEEKEVEK------LGKLQYSLDYDFQDNKLTVGILQCADLISMDSGGTSDPYVKV-FI 197

  Fly   399 TPEAHTKYTRWQRTKTVHKTRNPEFNETLQFVGVEPEELGNSLIYVALFDDDKYG-HDFLGAAKV 462
            .|:...||.    ||...||.||.|||:..| .:..:|||...:.::::|.|::. ||.:|..|:
Zfish   198 LPDKKKKYD----TKVHKKTLNPVFNESFVF-KIPYQELGGKTLVMSVYDYDRFSKHDIIGEVKL 257

  Fly   463 CLSTVHSTSQYRISVPLGVEDQYSNAAEMAQNWPNGKMLLSLCYNTKRRALVVNVKQCINLMAMD 527
            .::|:.      :..|: .|.:..::||..:....|.:.:||.|......|.|.:.:..||..||
Zfish   258 PMNTLD------LGQPI-EEWRDLDSAEKEEPEKLGDICISLRYVPTAGKLTVCILEAKNLKKMD 315

  Fly   528 NNGSSDPFVKIQLKPDAHKNKKHKTSVKWRTLNPIYNEEFYFEASPHDLNKEMLILTVWDKD-LG 591
            ..|.|||:|||||..:..:.||.||:||..||||.|||.|.||.....:.|.::::||:|.| :|
Zfish   316 VGGLSDPYVKIQLLQNGKRLKKKKTTVKKNTLNPYYNESFSFEIPLEQMQKIIVVVTVFDYDKIG 380

  Fly   592 KSNDFLGSLQLGAQSKGERLQQWLDCIRLPDHFHEKWHCL 631
            | ||.:|.:.:|:::.|...:.|.|.:..|.....:||.|
Zfish   381 K-NDAIGKIFIGSKASGTSQKHWSDMLANPRRPIAQWHPL 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rph	NP_572651.1	FYVE_like_SF	84..172	CDD:333710
		C2A_Rabphilin_Doc2	354..477	CDD:176000	38/123 (31%)
		C2B_Rabphilin_Doc2	499..631	CDD:176030	51/132 (39%)
syt2b	XP_005166211.1	Syt1_2_N	14..>96	CDD:425364
		C2A_Synaptotagmin-1-5-6-9-10	157..276	CDD:176031	38/131 (29%)
		C2B_Synaptotagmin-1	285..420	CDD:176047	52/135 (39%)