Protein Alignment Rph and Syt8

DIOPT Version :10

• Sequence 1: NP_572651.1
• Gene: Rph / 32002
• FlyBaseID: FBgn0030230
• Length: 638
• Species: Drosophila melanogaster
• Sequence 2: XP_006508695.1
• Gene: Syt8 / 55925
• MGIID: 1859867
• Length: 402
• Species: Mus musculus
• Alignment Length: 321
• Identity: 94/321 - (29%)
• Similarity: 137/321 - (42%)
• Gaps: 36/321 - (11%)

  Fly   320 DSSGSGSNNSGNSQTQSQYQQHQQQLQQHCRDPLLG----WLEIAISYREAFHSLDCTMVRARDL 380
            |....|..::.||.|     .|..|....|.:|..|    |..:.:|....|.|.: ..|..|..
Mouse    86 DKETVGLGSARNSTT-----THLVQPDVDCLEPCSGGDQQWGRLLLSLEYDFGSQE-IRVGLRQA 144

  Fly   381 PAMDAAGLADPYCKLNIITPEAHTKYTRWQRTKTVHKTRNPEFNETLQFVGVEPEELGNSLIYVA 445
            ..:.|.|.||||..:::.|...     |...||....|.:|.|.||..|: |.|.||..:.:.|.
Mouse   145 GNLKAEGTADPYAWVSVSTQSG-----RRHETKVHRGTLSPMFEETCCFL-VPPAELPKATLKVQ 203

  Fly   446 LFDDDKYG-HDFLGAAKVCLSTVH----STSQYRISVPLGVEDQYSNAAEMAQNWPNGKMLLSLC 505
            |:|..::. |:.||..::.|.||.    ..|.|::..|...|.:..           |::..||.
Mouse   204 LWDFKRFSEHEPLGELQLPLGTVDLQHVLESWYQLGPPGTTEPEQM-----------GELCFSLR 257

  Fly   506 YNTKRRALVVNVKQCINLMAMDNNGSSDPFVKIQLKPDAHKNKKHKTSVKWRTLNPIYNEEFYFE 570
            |.....:|.|.|.:...|    |.|.::.:|||||..:..|.||.|||.|..|..|.:||.|.|.
Mouse   258 YVPSSGSLTVVVLEARGL----NPGLAEAYVKIQLMLNQRKWKKSKTSSKKGTTTPYFNEAFVFL 318

  Fly   571 ASPHDLNKEMLILTVWDKDLGKSNDFLGSLQLGAQSKGERLQQWLDCIRLPDHFHEKWHCL 631
            .....|....|:|.||.:.|....:.:|.:.||:::.|:.||.|.|.:........:||.|
Mouse   319 VPVSQLQSVDLVLAVWARGLQLRTEPVGKVLLGSRASGQPLQHWADMLAHARRPIAQWHHL 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rph	NP_572651.1	FYVE_like_SF	84..172	CDD:333710
		C2A_Rabphilin_Doc2	354..477	CDD:176000	38/131 (29%)
		C2B_Rabphilin_Doc2	499..631	CDD:176030	43/131 (33%)
Syt8	XP_006508695.1	C2	122..240	CDD:472691	36/124 (29%)
		C2	249..379	CDD:472691	44/144 (31%)