Protein Alignment Rph and Syt7

DIOPT Version :9

• Sequence 1: NP_572651.1
• Gene: Rph / 32002
• FlyBaseID: FBgn0030230
• Length: 638
• Species: Drosophila melanogaster
• Sequence 2: XP_030106854.1
• Gene: Syt7 / 54525
• MGIID: 1859545
• Length: 719
• Species: Mus musculus
• Alignment Length: 580
• Identity: 145/580 - (25%)
• Similarity: 220/580 - (37%)
• Gaps: 150/580 - (25%)

  Fly   158 PKYDMPRSASATPIPNPGPGSMA--GDTRAVQSCH----------------ATPT---------- 194
            |..|..||..|.| ..||....|  |..|.||| |                :|.|
Mouse   182 PGEDALRSGGAAP-SEPGSSGKAGRGRWRMVQS-HLAAGKLNLSNFEDSTLSTATTLESIPSSAG 244

  Fly   195 -----RPARVKKLTIRVNDSSSSSSGH--SEPEDEVDTG---------VGIGVGVVGGGMAK-GI 242
                 ||..:.:........|.:..|.  |:|......|         .|......|.|.|: |.
Mouse   245 EPKCQRPRTLMRQQSLQQPLSQNQQGRQPSQPTTSQSLGQLQAHAASAPGSNPRAYGRGQARQGT 309

  Fly   243 ASTRLQREDSFRLRA--------YGSIR-------SFIDGGERKLS-------NSFFFN------ 279
            ::....|....|.|:        .|.||       ||::|....||       ...|.|
Mouse   310 SAGSKYRAAGGRSRSNPGSWDHVVGQIRNRGLDMKSFLEGRMVVLSLVLGLSEQDDFANIPDLQN 374

  Fly   280 --RQQSQR-------------------PSECPEYDSVSMSKLRRESSFLRRGSVSSSWSISDSSG 323
              .||:|.                   |.:.|..:|...::.|...|.|.....|....:|..|
Mouse   375 PGTQQNQNAQGDKRLPAGGKAVNTAPVPGQTPHDESDRRTETRSSVSDLVNSLTSEMLMLSPGS- 438

  Fly   324 SGSNNSGNSQTQSQYQQHQQQLQQHCRDPLLGWLEIAISYREAFHSLDCTMVRARDLPAMDAAGL 388
                             .:.:..:.|....||.::.::.|.....:|...:::|::|||.|.:|.
Mouse   439 -----------------EEDEAHEGCSRENLGRIQFSVGYNFQESTLTVKVMKAQELPAKDFSGT 486

  Fly   389 ADPYCKLNIITPEAHTKYTRWQRTKTVHKTRNPEFNETLQFVGVEPEELGNSLIYVALFDDDKYG 453
            :||:.|:.::..:.|.     ..||...|..||.:|||..|.|...|::...::|:.:.|.|::.
Mouse   487 SDPFVKIYLLPDKKHK-----LETKVKRKNLNPHWNETFLFEGFPYEKVVQRVLYLQVLDYDRFS 546

  Fly   454 -HDFLGAAKVCLSTVHSTSQYRISVPLGVEDQYSNAAEMAQNWPN-----------GKMLLSLCY 506
             :|.:|               .:|:||...|    ..:|...|.:           |::||||||
Mouse   547 RNDPIG---------------EVSIPLNKVD----LTQMQTFWKDLKPCSDGSGSRGELLLSLCY 592

  Fly   507 NTKRRALVVNVKQCINLMAMDNNGSSDPFVKIQLKPDAHKNKKHKTSVKWRTLNPIYNEEFYFEA 571
            |....:::||:.:..||.|||..|:|||:||:.|.....:.:|.||..|.|.||||:||.|.|:.
Mouse   593 NPSANSIIVNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTKKRNLNPIFNESFAFDI 657

  Fly   572 SPHDLNKEMLILTVWDKDLGKSNDFLGSLQLGAQSKGERLQQWLDCIRLPDHFHEKWHCL 631
            ....|.:..:|:||.|||....||.:|.:.|..:|....::.|.|.|..|.....:||.|
Mouse   658 PTEKLRETTIIITVMDKDKLSRNDVIGKIYLSWKSGPGEVKHWKDMIARPRQPVAQWHQL 717

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rph	NP_572651.1	PHD_SF	84..172	CDD:304600	6/13 (46%)
		C2A_Rabphilin_Doc2	354..477	CDD:176000	30/123 (24%)
		C2B_Rabphilin_Doc2	499..631	CDD:176030	52/131 (40%)
Syt7	XP_030106854.1	PHA03307	138..>343	CDD:223039	35/162 (22%)
		C2A_Synaptotagmin-7	451..575	CDD:176032	36/147 (24%)
		C2B_Synaptotagmin-7	583..718	CDD:176050	54/135 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000025
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910