Protein Alignment Rph and Syt5

DIOPT Version :9

• Sequence 1: NP_572651.1
• Gene: Rph / 32002
• FlyBaseID: FBgn0030230
• Length: 638
• Species: Drosophila melanogaster
• Sequence 2: NP_062223.1
• Gene: Syt5 / 54309
• RGDID: 3806
• Length: 386
• Species: Rattus norvegicus
• Alignment Length: 390
• Identity: 110/390 - (28%)
• Similarity: 168/390 - (43%)
• Gaps: 82/390 - (21%)

  Fly   303 ESSFLRRGSVSSSWSISD-SSGSG--------------SNNSGNSQTQSQYQQHQQQLQQHCR-- 350
            :||.:|:|:| .:|.::. ..|||              .......::|:|.|.|.|::::..|
  Rat    18 DSSRIRQGAV-PAWVLATILLGSGLLVFSSCFCLYRKRCRRRMGKKSQAQAQVHLQEVKELGRSY 81

  Fly   351 -----------DP-------------LLGWLEIAISYREAFHSLDCTMVRARDLPAMDAAGLADP 391
                       ||             .||.|:.::.|......|...:::|..|.|:|..|.:||
  Rat    82 IDKVQPEIEELDPSPSMPGQQVLDKHQLGRLQYSLDYDFQTGQLLVGILQAEGLAALDLGGSSDP 146

  Fly   392 YCKLNIITPEAHTKYTRWQRTKTVHKTRNPEFNETLQFVGVEPEELGNSLIYVALFDDDKYG-HD 455
            |..:.:: |:...::    .||...:|.||.|.||..| .|...|||..::.:|::|.|::. :|
  Rat   147 YVSVYLL-PDKRRRH----ETKVHRQTLNPHFGETFAF-KVPYVELGGRVLVMAVYDFDRFSRND 205

  Fly   456 FLGAAKVCLSTVHSTSQYRISVPLGVEDQYSNAAEMAQNWPN------------GKMLLSLCYNT 508
            .:|..:|.:|:|                   |.....|.|..            |.:..||.|..
  Rat   206 AIGEVRVPMSSV-------------------NLGRPVQAWRELQVAPKEEQEKLGDICFSLRYVP 251

  Fly   509 KRRALVVNVKQCINLMAMDNNGSSDPFVKIQLKPDAHKNKKHKTSVKWRTLNPIYNEEFYFEASP 573
            ....|.|.|.:..||..||..|.|||:||:.|.....|.:|.||::|..||||.|||.|.||...
  Rat   252 TAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPC 316

  Fly   574 HDLNKEMLILTVWDKD-LGKSNDFLGSLQLGAQSKGERLQQWLDCIRLPDHFHEKWHCLAPDNPA 637
            ..:.|..:.|||.|.| ||| |:.:|.:.:|....|..|:.|.|.:..|.....:||.|.|.:.|
  Rat   317 DQVQKVQVELTVLDYDKLGK-NEAIGRVAVGTAVGGAGLRHWADMLANPRRPIAQWHSLRPPDRA 380

  Fly   638  637
              Rat   381  380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rph	NP_572651.1	PHD_SF	84..172	CDD:304600
		C2A_Rabphilin_Doc2	354..477	CDD:176000	35/123 (28%)
		C2B_Rabphilin_Doc2	499..631	CDD:176030	51/132 (39%)
Syt5	NP_062223.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21		1/2 (50%)
		Syt1_2_N	6..76	CDD:425364	14/58 (24%)
		C2A_Synaptotagmin-1-5-6-9-10	108..230	CDD:176031	38/146 (26%)
		C2B_Synaptotagmin-1	240..374	CDD:176047	52/134 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000025
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910