Protein Alignment Rph and Sytl3

DIOPT Version :9

• Sequence 1: NP_572651.1
• Gene: Rph / 32002
• FlyBaseID: FBgn0030230
• Length: 638
• Species: Drosophila melanogaster
• Sequence 2: XP_006227950.1
• Gene: Sytl3 / 499017
• RGDID: 1561992
• Length: 609
• Species: Rattus norvegicus
• Alignment Length: 691
• Identity: 150/691 - (21%)
• Similarity: 252/691 - (36%)
• Gaps: 205/691 - (29%)

  Fly    38 EPLRPEEQEAIISVIRRNEEIEVAERQRVGRLVERVEKI-----KQHAVERGPNCCRLCGDTFGI 97
            |..:..|::.|:.|:.|::.::..|.:||..|...::.:     |..:.|....||..|..|.|:
  Rat     8 ESFKELERDIILRVLYRDQTVQSIEEERVRNLKTHLQHLRWKGAKSSSQEYKEKCCARCQQTLGL 72

  Fly    98 LRPQRILCEDCRQSVCTKCSVDINIRYHTSERSREIWLCRICSETREMWKKSGAWFFKG------ 156
            |..:..:|:.|...||::|.|.:        |....|.|.:|.|.|.:..|:|.|||:.
  Rat    73 LLNRGAVCQGCSHRVCSECRVFL--------RKTHAWKCTVCFEDRNVKIKTGEWFFEERARKFP 129

  Fly   157 ------------LPKYDMPRSASATPIPNPGP----------------GSMAGDTRAVQSCHATP 193
                        |..|....|..:...|.|.|                |...|..::|::...:.
  Rat   130 TAGRRETAGARLLQSYQRQSSKISVVPPTPPPLSESQCGGSPNRLQELGHFRGFNKSVENLFLSV 194

  Fly   194 TRPARVKKLTIRVNDSSSSS----------SGHSEPEDEVDTGVGIGVGVVGGGMAKGIASTRLQ 248
            |  .:::||:...||.:|..          .||:|...:.||.|             .:.|.:..
  Rat   195 T--TQMRKLSKSQNDMTSEKHLLAMDPRQCMGHTERRSQSDTAV-------------NVTSRKTS 244

  Fly   249 REDSFRLRAYGSIRSFIDGGERKLSNSFFFNRQQSQR-----------PSECPEYDSVSMSKLRR 302
            ..|.  |:|:                     .|:..|           |...|.:.:|.
  Rat   245 TPDI--LKAF---------------------HQEDPRHPPSPVLKQDTPPSSPTHSTVF------ 280

  Fly   303 ESSFLRRGSVSSSWSISDSSGSGSNNSGNSQTQSQYQQHQQQLQQHCRDPLLGWLEIAISYREAF 367
             |..||.||:.|..|.....|:..|.:                       :.|.:|.||.|....
  Rat   281 -SGGLRHGSLISVNSTCTEMGNFDNAN-----------------------VTGEIEFAIHYCVNS 321

  Fly   368 HSLDCTMVRARDLP-AMDAAGLADPYCKLNIITPEAHTKYTRWQRTKTVHKTRNPEFNETLQFVG 431
            |||:..:...::|. ..|.....:||.|..:: |:..::..|  :|:....|.:|.|.|||:: .
  Rat   322 HSLEICIKTCKNLAYGEDKRRKCNPYVKTYLL-PDRSSQGKR--KTRVQKNTLDPTFEETLKY-Q 382

  Fly   432 VEPEELGNSLIYVALFDDDKYGHDFLG--AAKVCLSTVHSTSQYRISVPLGVEDQYSNAAEMAQN 494
            |:|.:|....:.|:::        .||  |.:|.|.        .:.:||...|...:||:.|:.
  Rat   383 VDPAQLATRRLQVSVW--------HLGTLARRVFLG--------EVILPLATWDFEGSAAQNARW 431

  Fly   495 WP---------------NGKMLL----------SLCYNTKRRALVVNVKQCINLMAMDN-----N 529
            :|               ||::.:          .:....:...|.:|.:.|:.::...|     :
  Rat   432 YPLRAKAEKYEENIPQTNGELAVRAKLVLPVGPRMLQEAQEDQLALNGQLCLVVLGAKNLPVRSD 496

  Fly   530 GSSDPFVKIQLK-PDAHKNKKHKTSVKWRTLNPIYNEEFYFE-ASPHDLNKEMLILTVWDKDLGK 592
            |:.:.|||..|. ||..| .:.|:.|..:...|.:...|.|. .|...|.:..|.|||||:.:..
  Rat   497 GTLNSFVKGCLTLPDQQK-LRVKSPVLKKQACPQWKHSFVFNGVSSSQLRQSTLELTVWDQAMFG 560

  Fly   593 SND-FLGSLQLGAQSKG----------ERLQQWLDCIRLPD 622
            .|| .||..:||  |||          :...||...:..|:
  Rat   561 MNDRLLGEAKLG--SKGGAPGCTDSCSQSKLQWQKVLSSPN 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rph	NP_572651.1	PHD_SF	84..172	CDD:304600	26/105 (25%)
		C2A_Rabphilin_Doc2	354..477	CDD:176000	31/125 (25%)
		C2B_Rabphilin_Doc2	499..631	CDD:176030	37/152 (24%)
Sytl3	XP_006227950.1	PHD_SF	14..123	CDD:419867	33/116 (28%)
		FYVE_like_SF	60..108	CDD:333710	16/55 (29%)
		C2	308..435	CDD:417471	38/146 (26%)
		C2B_SLP_1-2-3-4	449..609	CDD:175987	39/154 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910