Protein Alignment Rph and Sytbeta

DIOPT Version :9

• Sequence 1: NP_572651.1
• Gene: Rph / 32002
• FlyBaseID: FBgn0030230
• Length: 638
• Species: Drosophila melanogaster
• Sequence 2: NP_648734.1
• Gene: Sytbeta / 39630
• FlyBaseID: FBgn0261090
• Length: 602
• Species: Drosophila melanogaster
• Alignment Length: 631
• Identity: 128/631 - (20%)
• Similarity: 210/631 - (33%)
• Gaps: 177/631 - (28%)

  Fly   136 CRICSETREMWKKSGAWFFKGLPKYDMPRSASATPIPNPGPGSMAGDTRAVQSCHATP------- 193
            |.:..:..|.|.:........:.:..:.|:::....|:....|.......|...|..|
  Fly     9 CWLAHKRIESWSRMAKERVGAVRRVTLDRNSADEGTPSGSGASSTAGGNGVSVVHILPIGEGSTT 73

  Fly   194 ------TRPARVKKLTIRVNDSSSSSSGHSE-----PEDEVDTGV------------------GI 229
                  |.|.....:|...:...|.|:|...     |.|..:..:                  |:
  Fly    74 PPPQPMTPPPSASSVTSTTSGIGSVSAGSVSDSCDLPTDSEEVAIAKECQPIQPASQLHGMHGGM 138

  Fly   230 G--------VGVVGGGMAKGIAST----------------RLQREDSFRLRAYGSIRSFID---- 266
            |        |...|..:.:|.|..                ||||..|.      |.:|.:|
  Fly   139 GLNHHHMGTVSATGTDILRGPAEVFHSPLHLHHQSRSFPPRLQRTPSI------SSQSSVDSAPS 197

  Fly   267 --GGERKLSNSF--FFNRQQSQRPSE--CPEYDSVSMSKLRRESSFLRRG--------------- 310
              .|.|..|...  |....:|..|||  .|.:.:.|.|.:|..|...|.|
  Fly   198 RHSGHRGSSPQIRTFGPDGRSSLPSEPGFPHHLARSPSPMRTISLDARCGSPAHSADPGDLRTPS 262

  Fly   311 -SVSSSWSISDSSGSGSNNSGNSQTQSQYQQHQQQLQQHCRDPLL-------------------- 354
             |.||..|::..||.|.:::|......:           |..|||
  Fly   263 PSQSSLASLAGGSGMGGSSAGKGVAGGR-----------CLSPLLIPPRSQPGVDPAMGPASPLG 316

  Fly   355 -------------------------GWLEIAISYREAFHSLDCT--MVRARDLPAMDAAGLADPY 392
                                     |.|.:.:.|  .:|..|.|  ::.|.:|..::..|..|||
  Fly   317 ALQPDLYRMPDGPVYLTAPESSHAVGRLHLRVKY--DYHLFDLTVHLIEAHNLSPIEEGGFRDPY 379

  Fly   393 CKLNIITPEAHTKYTRWQRTKTVHK-TRNPEFNETLQFVGVEPEELGNSLIYVALFDDDKYGH-D 455
            .:| ::.||..::    :|...:|: ..||.|::..:| .|..::|....:.:.:.|.|:|.| |
  Fly   380 VRL-MLQPEVDSR----KRQTHIHRGESNPYFDQHFKF-PVSRDQLQGKELILQVLDYDRYSHND 438

  Fly   456 FLGAAKVCLSTVHSTSQYRISVPLGVEDQYSNAAEMAQNWPNGKMLLSLCYNTKRRALVVNVKQC 520
            .:|..::      |.....:|..:.:........:..::.|  ::|.||.|..:...|.|.:.:.
  Fly   439 IIGEVRI------SVDGLDLSKSVEIWGDLLRTKKPKEDRP--ELLCSLNYLPQAERLTVVIMKA 495

  Fly   521 INLMAMDNNGSSDPFVKIQLKPDAHKNKKHKTSVKWR--TLNPIYNEEFYFEASPHDLNKEMLIL 583
            .||..:     .:|:|||.|..:..:.||.|||:...  ..|||:||.|.|....:.|:.  ..:
  Fly   496 RNLDTL-----QEPYVKIYLIQNGKRIKKKKTSITKSDDPTNPIWNEAFTFNLQSNYLHN--AAI 553

  Fly   584 TVWDKDLGKSNDFLGSLQLGAQSKGERLQQWLDCIRLPDHFHEKWH 629
            .::....|.....:|...||.|..|...|.|.|.|.........||
  Fly   554 EIYVVGAGSEATEIGCCGLGPQESGTGCQHWHDMINNARKPTAMWH 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rph	NP_572651.1	PHD_SF	84..172	CDD:304600	4/35 (11%)
		C2A_Rabphilin_Doc2	354..477	CDD:176000	31/171 (18%)
		C2B_Rabphilin_Doc2	499..631	CDD:176030	38/133 (29%)
Sytbeta	NP_648734.1	C2	341..463	CDD:301316	31/135 (23%)
		C2B_Synaptotagmin	473..601	CDD:175975	39/136 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468146
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000025
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840