Protein Alignment Rph and syt4

DIOPT Version :10

• Sequence 1: NP_572651.1
• Gene: Rph / 32002
• FlyBaseID: FBgn0030230
• Length: 638
• Species: Drosophila melanogaster
• Sequence 2: NP_956242.1
• Gene: syt4 / 335357
• ZFINID: ZDB-GENE-030131-7297
• Length: 439
• Species: Danio rerio
• Alignment Length: 293
• Identity: 81/293 - (27%)
• Similarity: 135/293 - (46%)
• Gaps: 32/293 - (10%)

  Fly   354 LGWLEIAISY---REAFHSLDCTMVRARDL----PAMDAAGLADPYCKLNIITPEAHTKYTRWQR 411
            ||.|..::.|   ::||      ||..::.    |..:.:..:|||.||.::..:.|.     .:
Zfish   167 LGTLFFSVEYNFEKKAF------MVHIKEAHGLSPTDEQSLTSDPYIKLTLLPEKKHK-----VK 220

  Fly   412 TKTVHKTRNPEFNETLQFVGVEPEELGNSLIYVALFDDDKYGHD-FLGAAKVCLSTVHSTSQYRI 475
            |:.:.||.:|.|:||..|.|:....:....::..:...|::..| .:|...|.|:.: ..|:.|:
Zfish   221 TRVLRKTLDPAFDETFSFYGIPFARVSQLALHFMVLSFDRFSRDEVIGETLVPLADI-DLSEGRV 284

  Fly   476 SVPLGVEDQYSNAAEMAQNWPNGKMLLSLCYNTKRRALVVNVKQCINLMAMDNNGSSDPFVKIQL 540
            .:...:..:     .:.::...|::||||||.:....|.|.|.:..:|...|::|.|||:||:.|
Zfish   285 LMSRDIIKK-----NIRRSAGRGELLLSLCYQSTTSTLTVVVLKARHLPKADSSGPSDPYVKVNL 344

  Fly   541 KPDAHKNKKHKTSVKWRTLNPIYNEEFYF----EASPHDLNKEMLILTVWDKDLGKSNDFLGSLQ 601
            .....:..|.||.||....||::||.|.|    |....|.:.|:|:|   |.|.......:|.|.
Zfish   345 FQGKKRVCKKKTHVKKCAPNPVFNELFVFDLPSEDGLRDTSVELLLL---DSDRTSRTPVIGRLV 406

  Fly   602 LGAQSKGERLQQWLDCIRLPDHFHEKWHCLAPD 634
            ||..|.|...:.|.:....|.....|||.|:.|
Zfish   407 LGTSSPGTAGEHWREICDHPRRQIAKWHALSED 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rph	NP_572651.1	FYVE_like_SF	84..172	CDD:333710
		C2A_Rabphilin_Doc2	354..477	CDD:176000	31/130 (24%)
		C2B_Rabphilin_Doc2	499..631	CDD:176030	47/135 (35%)
syt4	NP_956242.1	C2A_Synaptotagmin-4-11	166..292	CDD:176034	31/136 (23%)
		C2B_Synaptotagmin-4	301..437	CDD:176049	48/138 (35%)