Protein Alignment Rph and Syt1

DIOPT Version :10

• Sequence 1: NP_572651.1
• Gene: Rph / 32002
• FlyBaseID: FBgn0030230
• Length: 638
• Species: Drosophila melanogaster
• Sequence 2: NP_523460.2
• Gene: Syt1 / 33473
• FlyBaseID: FBgn0004242
• Length: 474
• Species: Drosophila melanogaster
• Alignment Length: 314
• Identity: 95/314 - (30%)
• Similarity: 145/314 - (46%)
• Gaps: 43/314 - (13%)

  Fly   332 SQTQSQYQQHQQQLQQHCRDPLLGWLEIAISYREAFHSLDCTMVRARDLPAMDAAGLADPYCKLN 396
            ::...:..:..:|.:|.     ||.|...:.|....:||..|:::|.:|||:|..|.:|||.|:.
  Fly   176 TENAEEGDEEDKQSEQK-----LGRLNFKLEYDFNSNSLAVTVIQAEELPALDMGGTSDPYVKVY 235

  Fly   397 IITPEAHTKYTRWQRTKTVHKTRNPEFNETLQFVGVEPEELGNSLIYVALFDDDKYG-HDFLGAA 460
            :: |:...|:    .||...||.:|.||||..|..:...:..|..:..|:||.|::. ||.:|..
  Fly   236 LL-PDKKKKF----ETKVHRKTLSPVFNETFTFKSLPYADAMNKTLVFAIFDFDRFSKHDQIGEV 295

  Fly   461 KVCLSTVHSTSQYRISVPLGVEDQYSNAAEMAQNWPN-------------GKMLLSLCYNTKRRA 512
            ||.|.|:                   :.|:..:.|.:             |.:..||.|......
  Fly   296 KVPLCTI-------------------DLAQTIEEWRDLVSVEGEGGQEKLGDICFSLRYVPTAGK 341

  Fly   513 LVVNVKQCINLMAMDNNGSSDPFVKIQLKPDAHKNKKHKTSVKWRTLNPIYNEEFYFEASPHDLN 577
            |.|.:.:..||..||..|.|||:|||.:..:..:.||.|||:|..||||.|||.|.||.....:.
  Fly   342 LTVVILEAKNLKKMDVGGLSDPYVKIAIMQNGKRLKKKKTSIKKCTLNPYYNESFSFEVPFEQIQ 406

  Fly   578 KEMLILTVWDKDLGKSNDFLGSLQLGAQSKGERLQQWLDCIRLPDHFHEKWHCL 631
            |..|::||.|.|...:::.:|...||....|..|:.|.|.:..|.....:||.|
  Fly   407 KICLVVTVVDYDRIGTSEPIGRCILGCMGTGTELRHWSDMLASPRRPIAQWHTL 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rph	NP_572651.1	FYVE_like_SF	84..172	CDD:333710
		C2A_Rabphilin_Doc2	354..477	CDD:176000	41/123 (33%)
		C2B_Rabphilin_Doc2	499..631	CDD:176030	48/131 (37%)
Syt1	NP_523460.2	Syt1_2_N	62..161	CDD:425364
		C2A_Synaptotagmin-1-5-6-9-10	192..316	CDD:176031	43/152 (28%)
		C2B_Synaptotagmin-1	326..461	CDD:176047	50/135 (37%)