Protein Alignment Rph and Syt15

DIOPT Version :10

• Sequence 1: NP_572651.1
• Gene: Rph / 32002
• FlyBaseID: FBgn0030230
• Length: 638
• Species: Drosophila melanogaster
• Sequence 2: NP_852682.1
• Gene: Syt15 / 319508
• MGIID: 2442166
• Length: 418
• Species: Mus musculus
• Alignment Length: 340
• Identity: 80/340 - (23%)
• Similarity: 139/340 - (40%)
• Gaps: 47/340 - (13%)

  Fly   313 SSSWSISDSSGSGSNNSGNSQTQSQYQQHQQQLQQHCRDPLLGWLEIAISYREAFHSLDCTMVRA 377
            :||....|:...||.|      ...|:..:...:....|..||.|..::.|::....|...:::|
Mouse   110 TSSAKPGDACEMGSIN------PELYKSPEDTSETGFPDGCLGRLWFSVEYQQESERLLVGLIKA 168

  Fly   378 RDL--PAMDAAGLADPYCKLNIITPEAHTKYTRWQRTKTVHKTRNPEFNETLQFVGVEPEELGNS 440
            :.|  |:...:.|.    ||:::..|     .|:.::||.||..||:|:|...| .|..:.:...
Mouse   169 QQLQVPSETCSTLV----KLHLLPDE-----RRFLQSKTKHKICNPQFDENFIF-QVSSKSVTQR 223

  Fly   441 LIYVALFD-DDKYGHDFLGAAKVCLSTVHSTSQYRISVPLGVE----DQYS------NAAEMAQN 494
            ::..:::. :.|..|..||               ::..||..|    |.:.      .|..:...
Mouse   224 VLKFSVYHVNKKRKHQLLG---------------QVLFPLKNETLAGDHHRIIWRDLEAKNLEPP 273

  Fly   495 WPNGKMLLSLCYNTKRRALVVNVKQCINLMAMDNNGSSDPFVKIQLKPDAHKNKKHKTSVKWRTL 559
            ...|.:...|.||.....|.|.|.:...|...::......|||:.|.......|..:||....::
Mouse   274 SEFGDIQFCLSYNDYLSRLTVVVLRAKGLQLQEDRSVVSVFVKVSLMNHNKFVKCKRTSAVLGSV 338

  Fly   560 NPIYNEEFYFEASPHDLNKEMLILTVWDKDLGKSNDFLGSLQLG--AQSKGERLQQWLDCIRLPD 622
            ||:|||.|.|:...::|:...|.|.|.....|..:..||.:.:|  ..::|:.|:.|.:.:|.|.
Mouse   339 NPVYNETFSFKVDTNELDTASLSLVVLQTTEGNKSSPLGRVVVGPYMYTRGKELEHWGEMLRKPK 403

  Fly   623 HFHEKWHCLA-PDNP 636
            ...::||.|. |..|
Mouse   404 ELVKRWHALCRPTEP 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rph	NP_572651.1	FYVE_like_SF	84..172	CDD:333710
		C2A_Rabphilin_Doc2	354..477	CDD:176000	27/125 (22%)
		C2B_Rabphilin_Doc2	499..631	CDD:176030	36/133 (27%)
Syt15	NP_852682.1	C2A_Synaptotagmin-15-17	146..266	CDD:176036	30/144 (21%)
		C2	276..413	CDD:472691	37/136 (27%)