Protein Alignment Rph and PsGEF

DIOPT Version :10

• Sequence 1: NP_572651.1
• Gene: Rph / 32002
• FlyBaseID: FBgn0030230
• Length: 638
• Species: Drosophila melanogaster
• Sequence 2: NP_996333.4
• Gene: PsGEF / 31224
• FlyBaseID: FBgn0264598
• Length: 2777
• Species: Drosophila melanogaster
• Alignment Length: 294
• Identity: 62/294 - (21%)
• Similarity: 109/294 - (37%)
• Gaps: 68/294 - (23%)

  Fly   394 KLNIITPEAHTKYTRWQRTKTVHKTRNPEFNETLQFVGVEPEELGNSLIYVALFDDDKYGHDF-- 456
            ::.:.|| .|.|..|..|.|..|||......::.|...:||.:|..|......|.......|.
  Fly   163 EMEVRTP-THLKRQRVVRRKNPHKTTTINQTQSHQAKKLEPLQLVPSTKRCLSFSSSSASSDLDE 226

  Fly   457 ----------LGAAKV-----CLSTVHSTSQYRISVPLGVEDQYSNAAEMAQNWPNGKMLLSLCY 506
                      |.:...     |.:|..|.|....|         :..|:|..: ..|.:.:|:.:
  Fly   227 DEQQVAKRSSLASPTTTPPSHCTTTTSSISSSSSS---------NGGADMEAS-QRGSIDVSIAF 281

  Fly   507 NTKRRALVVNVKQCINLMAM--DNNGSSDPFVKIQLKPDAH-------------KNKKHKTSVKW 556
            :.|.:.|.|:|.:|.:|...  ..|||.:.:||:.|...|.             .:...:|:|..
  Fly   282 DAKEQQLNVHVIRCRDLQRSHGSGNGSINAYVKVALSGGAQPPGYGGHSSGGSMSSGYQRTAVHR 346

  Fly   557 RTLNPIYNEEFYFE-ASPHDLNKEMLILTVWDKDLG------KSNDFLGSLQLGAQSK-GERL-- 611
            .:..|.:::.|.|: :|..:...:.|.|.||.:|..      ..:::...::.|.:.: .|||
  Fly   347 HSGRPYFDQRFNFQISSGEETAGQYLQLAVWHRDRHLNSVPVTQSEWQARVKSGTERRTAERLAK 411

  Fly   612 ----------QQWLDCIRLPDHFHEKWHCLAPDN 635
                      .::|.|...|  .:|..|   ||:
  Fly   412 LENAGNEAKRSEFLGCSTFP--LNELVH---PDS 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rph	NP_572651.1	FYVE_like_SF	84..172	CDD:333710
		C2A_Rabphilin_Doc2	354..477	CDD:176000	22/99 (22%)
		C2B_Rabphilin_Doc2	499..631	CDD:176030	34/166 (20%)
PsGEF	NP_996333.4	DUF4799	<99..209	CDD:318308	14/46 (30%)
		C2	286..>381	CDD:425499	22/94 (23%)
		PDZ_canonical	645..716	CDD:483948
		RhoGEF	835..1007	CDD:470622
		PRK12323	<2304..>2415	CDD:481241