Protein Alignment Rph and tcb2

DIOPT Version :10

• Sequence 1: NP_572651.1
• Gene: Rph / 32002
• FlyBaseID: FBgn0030230
• Length: 638
• Species: Drosophila melanogaster
• Sequence 2: NP_587862.1
• Gene: tcb2 / 2539477
• PomBaseID: SPCP31B10.06
• Length: 1188
• Species: Schizosaccharomyces pombe
• Alignment Length: 328
• Identity: 71/328 - (21%)
• Similarity: 109/328 - (33%)
• Gaps: 113/328 - (34%)

  Fly   376 RARDLPAMDAAGLADPYCKLNIITPEAHTKYTRWQRTKTVHKTRNPEFNETLQFVGVEPEEL-GN 439
            ||.||...|..||:|.|     ||...|........|:.|.:..||.:|| ..|:.|.|::: ..
pombe   477 RAEDLSKQDVNGLSDAY-----ITVGFHKFGKPLYCTRVVKQDLNPIWNE-YAFIPVFPDQVKAG 535

  Fly   440 SLIYVALFDDDKYG-HDFLGAAKVCL-------STVH---------------------------- 468
            ..|.:.|:|.|::. .|.:|..|:.|       ..:|
pombe   536 EKISIELWDSDRFSPDDVVGRTKIGLHLLIQDSGKMHERCDTLTGISEDTSLPGRVFYEIGYFPR 600

  Fly   469 -------STSQYRISVPLGVED---------QYSNAAEMA-------QNWPNGKMLLSLCYNTKR 510
                   .||.:.|::|..:.|         ...|..|.|       :.:|:|  :||.
pombe   601 AEFKPSLKTSGHDITIPRSMRDDPAFQNPHGSLDNKEEEAAVTTAPDEEYPSG--ILSF------ 657

  Fly   511 RALVVNVKQCINLMA---------MDNNGSSDPFVKI--------------QLKPDAHKNKKHKT 552
                 .|.|.:||..         :..|.::.|...:              .:..|......:||
pombe   658 -----TVHQAVNLQMNHPTGTFGNVSGNYNTSPAQSVGDVTAEEGSELPSSYVCVDLDDTLVYKT 717

  Fly   553 SVKWRTLNPIYN---EEFYFEASPHDLNKEMLILTVWDKDLGKSNDFLGSLQL---GAQSKGERL 611
            ..|..|.|||||   |:|.     .|....||..||.|..|.:.:..||.:.:   ...:...:|
pombe   718 RTKVFTSNPIYNAGSEKFV-----KDWRNAMLCFTVRDFKLREHDSILGVVNIPLATTLTTSSQL 777

  Fly   612 QQW 614
            .:|
pombe   778 TKW 780

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rph	NP_572651.1	FYVE_like_SF	84..172	CDD:333710
		C2A_Rabphilin_Doc2	354..477	CDD:176000	33/144 (23%)
		C2B_Rabphilin_Doc2	499..631	CDD:176030	31/145 (21%)
tcb2	NP_587862.1	COG5038	7..1188	CDD:227371	71/328 (22%)