Protein Alignment Rph and Syt2

DIOPT Version :9

• Sequence 1: NP_572651.1
• Gene: Rph / 32002
• FlyBaseID: FBgn0030230
• Length: 638
• Species: Drosophila melanogaster
• Sequence 2: XP_038946276.1
• Gene: Syt2 / 24805
• RGDID: 3804
• Length: 499
• Species: Rattus norvegicus
• Alignment Length: 553
• Identity: 136/553 - (24%)
• Similarity: 228/553 - (41%)
• Gaps: 131/553 - (23%)

  Fly   125 HTSERSR------EIWLCRICSETREM-------WKK----SGAWFFKGLPKYDMPR--SASATP 170
            ||..:|.      |:..|......||.       |.|    ...|....:|...|..  ..:..|
  Rat    24 HTHTQSSLPVSGPELDFCLSVQNRRERGRCCRRGWSKLDPLERRWAGPAVPSATMRNIFKRNQEP 88

  Fly   171 IPNPGPGSMAGDTRAVQSCHATPTRPARVKKLTIRVNDSSSSSSGHSEPEDEVDTGVGIGVGVVG 235
            |..|     |..|..:....|.|.             |:|:.|:|..|
  Rat    89 IVAP-----ATTTATMPLAPAAPV-------------DNSTESTGTGE----------------- 118

  Fly   236 GGMAKGIASTRLQREDSFRLRAYGSIRSFIDGGERKLSNSFFFNRQQSQRPSECPEYDSVSMSKL 300
                        .:||.|                .||.:.||  .:.::.|  .|.:..::|:.:
  Rat   119 ------------SQEDMF----------------AKLKDKFF--NEINKIP--LPPWALIAMAVV 151

  Fly   301 ------------------RRESSFLRRG-SVSSSWSISD-SSGSGSNNSGNSQTQSQYQQHQQQL 345
                              :::.:...:| .:.::.::.| ..|...:::....|:.:.:..:::.
  Rat   152 AGLLLLTCCFCICKKCCCKKKKNKKEKGKGMKNAMNMKDMKGGQDDDDAETGLTEGEGEGEEEKE 216

  Fly   346 QQHCRDPLLGWLEIAISYREAFHSLDCTMVRARDLPAMDAAGLADPYCKLNIITPEAHTKYTRWQ 410
            .::     ||.|:.::.|....:.|...:::|.:|||:|..|.:|||.|: .:.|:...||
  Rat   217 PEN-----LGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKV-FLLPDKKKKY---- 271

  Fly   411 RTKTVHKTRNPEFNETLQFVGVEPEELGNSLIYVALFDDDKYG-HDFLGAAKVCLSTVHSTSQYR 474
            .||...||.||.||||..| .|..:|||...:.:|::|.|::. ||.:|..||.::||.
  Rat   272 ETKVHRKTLNPAFNETFTF-KVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVD------ 329

  Fly   475 ISVPLGVEDQYSNAAEMAQNWPN--GKMLLSLCYNTKRRALVVNVKQCINLMAMDNNGSSDPFVK 537
            :..|:   :::.:.....:..|.  |.:..||.|......|.|.:.:..||..||..|.|||:||
  Rat   330 LGQPI---EEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVK 391

  Fly   538 IQLKPDAHKNKKHKTSVKWRTLNPIYNEEFYFEASPHDLNKEMLILTVWDKD-LGKSNDFLGSLQ 601
            |.|..:..:.||.||:||.:||||.:||.|.||.....:.|..:::||.|.| ||| |:.:|.:.
  Rat   392 IHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGK-NEAIGKIF 455

  Fly   602 LGAQSKGERLQQWLDCIRLPDHFHEKWHCLAPD 634
            :|:.:.|..|:.|.|.:..|.....:||.|.|:
  Rat   456 VGSNATGTELRHWSDMLANPRRPIAQWHSLKPE 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rph	NP_572651.1	PHD_SF	84..172	CDD:304600	13/65 (20%)
		C2A_Rabphilin_Doc2	354..477	CDD:176000	43/123 (35%)
		C2B_Rabphilin_Doc2	499..631	CDD:176030	50/132 (38%)
Syt2	XP_038946276.1	Syt2_N	81..193	CDD:409249	24/178 (13%)
		C2A_Synaptotagmin-1-5-6-9-10	219..341	CDD:176031	44/141 (31%)
		C2B_Synaptotagmin-1	351..486	CDD:176047	51/135 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000025
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910