Protein Alignment Rph and Syt17

DIOPT Version :10

• Sequence 1: NP_572651.1
• Gene: Rph / 32002
• FlyBaseID: FBgn0030230
• Length: 638
• Species: Drosophila melanogaster
• Sequence 2: NP_620204.1
• Gene: Syt17 / 192189
• RGDID: 708576
• Length: 474
• Species: Rattus norvegicus
• Alignment Length: 468
• Identity: 117/468 - (25%)
• Similarity: 189/468 - (40%)
• Gaps: 84/468 - (17%)

  Fly   205 RVNDSSSSSSGHSEPEDEVDTGVGIGVGVVGGGMAKGIASTRLQREDSFRLRAYGSI----RSFI 265
            |..:||...|.    ||||:.     :|.........:.::|...:|...:.....:    |:..
  Rat    33 RCYESSCCQSS----EDEVEI-----LGPFPAQTPPWLMASRSNDKDGDSVHTASDVPLTPRTNS 88

  Fly   266 DGGERKLS----NSFFFNRQ----QSQRPSECP-------EYDSVSMSKLRRESSFLRRGSVSSS 315
            ..|.|..|    :::...|:    .|:|||. |       |:..:|..|...:.|.|||......
  Rat    89 PDGRRSSSDTSKSTYSLTRRISSLDSRRPSS-PLIDIKPIEFGVLSAKKEPIQPSVLRRTYTPDD 152

  Fly   316 ---------WSISDSSGSGSNNSGNSQTQSQYQQHQQQLQQHCRDPLLGWLEIAISYREAFHSLD 371
                     :|: ||:....::..:.:..|:||              ||.|..:..|....:.|.
  Rat   153 YFRKFEPRLYSL-DSNLDDVDSLTDEEIMSKYQ--------------LGMLHFSTQYDLLHNHLT 202

  Fly   372 CTMVRARDLP--------AMDAAGLADPYCKLNIITPEAHTKYTRWQRTKTVHKTRNPEFNETLQ 428
            ..::.|||||        ..|.|. ::||.|:.::..:.::|.|..:|     ||:.|.|.|...
  Rat   203 VRVIEARDLPPPISHDGSRQDMAH-SNPYVKICLLPDQKNSKQTGVKR-----KTQKPVFEERYT 261

  Fly   429 FVGVEPEELGNSLIYVALFDDDKYG-HDFLG--AAKVC-LSTVHSTSQYRISVPLGVEDQYSNAA 489
            | .:...|.....:.:.:.|.||:. |..:|  |..:| :..|.....::..:|     ...|..
  Rat   262 F-EIPFLEAQRRTLLLTVVDFDKFSRHCVIGKVAVPLCEVDLVKGGHWWKALIP-----SSQNEV 320

  Fly   490 EMAQNWPNGKMLLSLCYNTKRRALVVNVKQCINLMAMDNNGSSDPFVKIQLKPDAHKNKKHKTSV 554
            |:      |::||||.|......|.|::.:...|:..|.:..|||||||||.......|..|||.
  Rat   321 EL------GELLLSLNYLPSAGRLNVDIIRAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTKKTSF 379

  Fly   555 KWRTLNPIYNEEFYFEASPHDLNKEMLILTVWDKDLGKSNDFLGSLQLGAQSKG-ERLQQWLDCI 618
            ...|::|.|||.|.|:....:|....|:.||:..::..||||:|.:.:|..|.| .....|...:
  Rat   380 LRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSNDFIGRIVIGQYSSGPSESNHWRRML 444

  Fly   619 RLPDHFHEKWHCL 631
            .......|:||.|
  Rat   445 NTHRTAVEQWHSL 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rph	NP_572651.1	FYVE_like_SF	84..172	CDD:333710
		C2A_Rabphilin_Doc2	354..477	CDD:176000	33/134 (25%)
		C2B_Rabphilin_Doc2	499..631	CDD:176030	45/132 (34%)
Syt17	NP_620204.1	C2B_Synaptotagmin-17	323..457	CDD:176055	46/133 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	60..117		8/56 (14%)
		C2A_Synaptotagmin-15-17	186..314	CDD:176036	32/134 (24%)