Protein Alignment Rph and snt-2

DIOPT Version :10

• Sequence 1: NP_572651.1
• Gene: Rph / 32002
• FlyBaseID: FBgn0030230
• Length: 638
• Species: Drosophila melanogaster
• Sequence 2: NP_497261.2
• Gene: snt-2 / 185680
• WormBaseID: WBGene00004922
• Length: 369
• Species: Caenorhabditis elegans
• Alignment Length: 337
• Identity: 102/337 - (30%)
• Similarity: 149/337 - (44%)
• Gaps: 82/337 - (24%)

  Fly   321 SSGSGSNNSGNSQTQSQYQQHQQQLQQHCRDPLLGWLEIAISYREAFHSLDCTMVRARDLPAMDA 385
            |||:.....||...:.:|...|.:                         |..|:|.|.||||||.
 Worm    76 SSGALIKQYGNIHFRVEYDFEQSK-------------------------LSVTIVSASDLPAMDR 115

  Fly   386 AGLADPYCKLNIITPEAHTKYTRWQRTKTVHKTRNPEFNETLQFVGVEPEELGNSLIYVALFD-- 448
            .|::|||.|:.:: ||...|:    .|:.:..|.||.:|||.|| .:...||.:..:.:.::|
 Worm   116 NGMSDPYVKVYVL-PERKQKF----ETRIIRNTLNPTYNETFQF-SIPFNELHSKTLMLVVYDYD 174

  Fly   449 ----DDKYGHDFLGAAKVCLSTVHSTSQYRISVPL-----GVEDQYSNAAEMAQNWPNGKMLL-S 503
                |||.|                    ::||||     |:........:..:.....:..| .
 Worm   175 RLSKDDKMG--------------------QLSVPLESIDFGITTDIERPLQKPEKDDEKECRLGD 219

  Fly   504 LCYNTKRR----ALVVNVKQCINLMAMDNNGSSDPFVKIQLKPDAHKNKKHKTSVKWRTLNPIYN 564
            :|::|:.|    .:.:.:.:..||..||..|||||:|||.|........|.|||.|::||||.||
 Worm   220 ICFSTRYRPATGTVTLTIMEARNLKKMDVGGSSDPYVKIYLHHGRKLLSKKKTSRKYKTLNPYYN 284

  Fly   565 EEFYFEASPHDLNKEMLILTVWDKDLGKSNDFLGSLQLGAQSKGERL--------QQWLDCI--R 619
            |.|.|:..||.:.|..||::|||.|....|||:|.:.||  ||...|        :||.:.:  |
 Worm   285 ESFQFKIEPHMIEKVHLIVSVWDYDKMSKNDFIGEVTLG--SKHLNLPQITHACSEQWAEMMTSR 347

  Fly   620 LPDHFHEKWHCL 631
            .|   ..:||.|
 Worm   348 RP---VVQWHTL 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rph	NP_572651.1	FYVE_like_SF	84..172	CDD:333710
		C2A_Rabphilin_Doc2	354..477	CDD:176000	34/128 (27%)
		C2B_Rabphilin_Doc2	499..631	CDD:176030	55/146 (38%)
snt-2	NP_497261.2	C2	85..206	CDD:472691	43/171 (25%)
		C2B_Synaptotagmin-1	217..357	CDD:176047	56/145 (39%)