DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rph and snt-7

DIOPT Version :9

Sequence 1:	NP_572651.1	Gene:	Rph / 32002	FlyBaseID:	FBgn0030230	Length:	638	Species:	Drosophila melanogaster
Sequence 2:	NP_510526.2	Gene:	snt-7 / 181615	WormBaseID:	WBGene00011682	Length:	416	Species:	Caenorhabditis elegans

Alignment Length:	321	Identity:	70/321 - (21%)
Similarity:	135/321 - (42%)	Gaps:	51/321 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   269 ERKLSNSFFFNRQQSQRPSECPEYDSVSMSKLRRESSFLRRGSVSSSWSISDSSGSGSNNSGNSQ 333
            |.||..||         ||                :|.:.:|.::|.:.|..:. .|:.:..::.
Worm    78 ESKLGESF---------PS----------------TSSIPKGDLTSLFMIPKAK-KGARSMFSNL 116

  Fly   334 TQSQYQQHQQQL----QQHCRD---PLLGWLEIAISYREAFHSLDCTMVRARDLPAMDAAGLADP 391
            .|:|:.:...|.    :..|..   ..:|.:::::|:....:.|..|:|:|.|||......|.:|
Worm   117 HQNQFDRGLYQFPTGDESACSSVTMSAVGSIQLSVSHDVNLNLLTVTIVKAVDLPTKREDDLPNP 181

  Fly   392 YCKLNIITPEAHTKYTRWQRTKTVHKTRNPEFNETLQFVGVEPEELGNSLIYVALFDDDKYGHD- 455
            :.|:::..|::.......| |||.:.|.:|..||...| .|..:::....:.|.::|.|::..|
Worm   182 FMKVSLEIPDSKKPNVDHQ-TKTYNGTASPLINEDFYF-SVTSQQVSICRLEVMVYDYDQFSVDE 244

  Fly   456 FLGAAKVCLSTVHSTSQYRI-----SVPLGVEDQYSNAAEMAQNWPNGKMLLSLCYNTKRRALVV 515
            .:|...:.|..::...::.:     :..|..||        .:|...|::|.:|.|.:..:.|.:
Worm   245 CVGYCWLTLGRINEHFEHDLPTLFWAEVLPYED--------GENKGYGQVLFALSYLSHAQRLTM 301

  Fly   516 NVKQCINLMAMDNNGSSDPFVKIQLKPDAHKNKKHKTSVKWRTLNPIYNEEFYFEASPHDL 576
            |:.:..|:..  .||.:.......|..:....||.|||:|....:..:||...|....|.|
Worm   302 NIFKVRNVRF--RNGGNVALRVTLLDGEEKPLKKKKTSLKKAARSVQFNECLTFSIPKHTL 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rph	NP_572651.1	PHD_SF	84..172	CDD:304600
		C2A_Rabphilin_Doc2	354..477	CDD:176000	29/128 (23%)
		C2B_Rabphilin_Doc2	499..631	CDD:176030	20/78 (26%)
snt-7	NP_510526.2	C2	145..257	CDD:387358	29/113 (26%)
snt-7	NP_510526.2	C2	283..>374	CDD:387358	21/80 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000025
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910