DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rph and esyt-2

DIOPT Version :9

Sequence 1:	NP_572651.1	Gene:	Rph / 32002	FlyBaseID:	FBgn0030230	Length:	638	Species:	Drosophila melanogaster
Sequence 2:	NP_001366808.1	Gene:	esyt-2 / 175882	WormBaseID:	WBGene00020443	Length:	808	Species:	Caenorhabditis elegans

Alignment Length:	170	Identity:	42/170 - (24%)
Similarity:	84/170 - (49%)	Gaps:	8/170 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   319 SDSSGS-GSNNSGNSQTQSQYQ-QHQQQLQQHCRDPLLGWLEIAISYREAFHSLDCTMVRARDLP 381
            |||.|| .|:...||:....:: :|:.:.::...|...|.:||.|.:.:..:.|...::|.|||.
Worm   639 SDSQGSLNSHGRSNSRLGRLFRSKHEMKKRETRADENRGEIEIQIDFDDLVNQLKIALIRCRDLM 703

  Fly   382 AMDAAGLADPYCKLNIITPEAHTKYTRWQRTKTVHKTRNPEFNETLQFVGVEPEELGNSLIYVAL 446
            ..|.....:||..:.::..:.:.:..: ::|.|...||:|.|:..:: :.:.|.:|.|..:.:.:
Worm   704 TFDKKDQCNPYVSVKLVALDGNKEVFK-KKTPTAKNTRHPHFDNHVE-IDINPSDLLNHKVVINV 766

  Fly   447 FDDDKYG----HDFLGAAKVCLSTVHSTSQYRISVPLGVE 482
            .||..||    ...||..::.|.::.:....:..:||.||
Worm   767 KDDTNYGTFVAKPVLGCLEIRLDSLMNRQLSQRWIPLSVE 806

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rph	NP_572651.1	PHD_SF	84..172	CDD:304600
		C2A_Rabphilin_Doc2	354..477	CDD:176000	28/126 (22%)
		C2B_Rabphilin_Doc2	499..631	CDD:176030
esyt-2	NP_001366808.1	SMP_LBD	83..260	CDD:293652
		C2A_C2C_Synaptotagmin_like	276..394	CDD:176037
		C2B_Synaptotagmin-like	424..528	CDD:176015
		C2	691..800	CDD:214577	24/110 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910