Protein Alignment Rph and LOC1275499

DIOPT Version :10

• Sequence 1: NP_572651.1
• Gene: Rph / 32002
• FlyBaseID: FBgn0030230
• Length: 638
• Species: Drosophila melanogaster
• Sequence 2: XP_061516541.1
• Gene: LOC1275499 / 1275499
• VectorBaseID: AGAMI1_008322
• Length: 514
• Species: Anopheles gambiae
• Alignment Length: 495
• Identity: 125/495 - (25%)
• Similarity: 189/495 - (38%)
• Gaps: 115/495 - (23%)

  Fly   152 WFFKGLPKYDMPRSAS---------ATPIPNPGPGSMAGDTRAVQSCHATPTR-----PARVKKL 202
            |:.|.|.:....|.|:         ..||.. ...::||.:|.:...|.:|..     |....:.
Mosquito    51 WYEKNLLESAKEREAAQRGSHEGHITCPIAY-NVDAVAGTSRYLNRAHGSPQARADHPPFWASQG 114

  Fly   203 TIRVNDSSSSSSGHSEPEDEVDTGVGIGVGVVGGGMAKGIASTRLQREDSFRLRAYGSIRSFIDG 267
            ..|.:||....   .:..||..||                       |||
Mosquito   115 LYRKSDSRGQL---IDTSDEETTG-----------------------EDS--------------- 138

  Fly   268 GERKLSNSFFFNRQQSQRPSECPEYDSVSMSKLRRESSFLRRGSVSSSWSISDSSGSGSNNSGNS 332
            |:...|:|    |.....||     .:|:::...:....:.......:.|:..:...||..|...
Mosquito   139 GDSACSSS----RSVIAAPS-----GAVAIASTGKHVVLVTSSPAKPTTSMVATVAGGSRGSATG 194

  Fly   333 QTQSQYQQHQ----------QQLQQHCRDPL-----LGWLEIAISYREAFHSLDCTMVRARDLPA 382
            .|.|:....|          .......||.|     .|.:.:.:||..|...|:..:|.|:||..
Mosquito   195 ATASKVDTSQGTKIDMLDSASTCSTVSRDELGGEDARGAIHLTLSYDPAAGILNVKLVEAQDLQP 259

  Fly   383 MDAAGLADPYCKLNIITPEAHTKYTRWQRTKTVHKTRNPEFNETLQFVGVEPEELGNSLIYVALF 447
            .|.:|.||||.|:.:: |:   :...|| |:...||.||.|:|...| .|....:|...:.:.||
Mosquito   260 QDFSGTADPYAKIRLL-PD---RNNMWQ-TRIHKKTLNPVFDEDFVF-EVRSATIGRRTLEILLF 318

  Fly   448 DDDKYG-HDFLGA-----AKVCLSTVHSTSQYRISV--PLGVEDQYSNAAEMAQNWPNGKMLLSL 504
            |.|.|. |..:|.     |:|||:.       ||.:  ||....:..|..::      |.:::||
Mosquito   319 DFDAYSRHVCIGGVQFPLAQVCLAE-------RIDIWRPLLPYTEQDNKQDL------GDLMVSL 370

  Fly   505 CYNTKRRALVVNVKQCINLMAMD-NNGSSDPFVKIQL-KPDAHKNKKHKTSVKWRTLNPIYNEEF 567
            .|......|.|.:.:..||..:| ...||||:||:.| ..|..:.||.||:|...|..|:|||..
Mosquito   371 SYQPAAEKLTVVIIKARNLRVIDGTRNSSDPYVKVCLYNADGRRLKKRKTTVARNTTAPVYNEAL 435

  Fly   568 YFEASP---HDLNKEMLILTVWDKDLGKSNDFLGSLQLGA 604
            .|:.|.   .|.:.|..:|  .|..||| |:.||...:|:
Mosquito   436 TFDISRETLRDCSIEFQVL--HDSLLGK-NETLGRATVGS 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rph	NP_572651.1	FYVE_like_SF	84..172	CDD:333710	6/28 (21%)
		C2A_Rabphilin_Doc2	354..477	CDD:176000	42/128 (33%)
		C2B_Rabphilin_Doc2	499..631	CDD:176030	39/111 (35%)
LOC1275499	XP_061516541.1	None