Protein Alignment Rph and LOC1272553

DIOPT Version :10

• Sequence 1: NP_572651.1
• Gene: Rph / 32002
• FlyBaseID: FBgn0030230
• Length: 638
• Species: Drosophila melanogaster
• Sequence 2: XP_061513620.1
• Gene: LOC1272553 / 1272553
• VectorBaseID: AGAMI1_002607
• Length: 543
• Species: Anopheles gambiae
• Alignment Length: 586
• Identity: 145/586 - (24%)
• Similarity: 216/586 - (36%)
• Gaps: 151/586 - (25%)

  Fly   101 QRILCEDCRQSVCTKCSVDI----NIRYHTSERSREIWLCRICSETREMWKKSGAWFFKGLPKYD 161
            ::|..:||.   .|..||.|    ::.:|:           |.|||      .|....:..|...
Mosquito    53 RKINLQDCN---VTSGSVPIQPASSVVHHS-----------ISSET------LGTGAVEVTPSPL 97

  Fly   162 MPRSASATPIPNPGPGSMAGDTRAVQSCHATPTRPARVKKLTIRVNDSSSS----SSGHSEPEDE 222
            .| :.|||.......|:  .|||....|     |||.....|...|:|..|    ||.:.|.
Mosquito    98 QP-TLSATGSTKKSYGT--SDTRTGPGC-----RPAHAAASTASRNNSMESVHSRSSSYRES--- 151

  Fly   223 VDTGVGIGVGVVGGGMAKGIASTRLQREDSFRLRAYGS---IRSF-------------------- 264
                       |...|....:.||....|:..||...|   :|:|
Mosquito   152 -----------VPKFMTHANSDTRSTTSDNLILRKSRSPSPMRTFSLEGRFPIGGPSNHSAAAVL 205

  Fly   265 IDGGER--KLSNSFFFNRQQSQRPSECPEYDSVSMSKLRRESSFLRRGSVSSSWSISDSSGSGSN 327
            .||.||  |.|.:...: ..|.|....|:         :|.|:|....|::...::.||. .||.
Mosquito   206 ADGTERGSKASLASVVS-GGSPRDFSSPK---------KRNSTFSGVVSLAGDGNVPDSP-IGSI 259

  Fly   328 NSGNSQTQSQYQQHQQQLQQHCRDP----------LLGWLEIAISYREAFHSLDCTMVRARDLPA 382
            .|.:|::..:            |.|          :||...:.:.|..:...|...:|.|:||..
Mosquito   260 RSDSSRSPRR------------RVPVILAANDIHSVLGRFHLRLKYDGSKEELLVHLVEAQDLTP 312

  Fly   383 MDAAGLADPYCKLNIITPEAHTKYTRWQRTK--TVHKTR-NPEFNETLQFVGVEPEELGNSLIYV 444
            ....|..|||.|:.:...|.       |||:  .||:|. :|.|::.|.| .::|..|..|...:
Mosquito   313 AGDTGFRDPYVKMYLEPDEE-------QRTQQTAVHRTETHPYFDQQLSF-PLKPRNLVKSNFVL 369

  Fly   445 ALFDDDKYGHD-FLGAAKVCLSTVHSTSQYRISVPLGVEDQYSNAAEMAQNWPNGKMLLSLCYNT 508
            .|.|.|::.|| .:|..:..|:|:..:........:.|.......||         :|:||.|..
Mosquito   370 QLLDYDRFSHDEVVGEIRFLLNTLDLSGCELWGDLIAVRKPSETTAE---------LLISLSYLP 425

  Fly   509 KRRALVVNVKQCINLMAMDNNGSSDPFVKIQLKPDAHKNKKHKTSVKWRTL---NPIYNEEFYFE 570
            :...|.|.|.:..||..     |.:||||:.|..:..:.||.|||. .|.|   |||:||.|.||
Mosquito   426 QAERLTVVVMKAKNLSI-----SHEPFVKLYLLVNDKRTKKRKTSA-IRALDPTNPIWNEAFTFE 484

  Fly   571 ---ASPHDLNKEMLILT--VWDKDLGKSNDFLGSLQLGAQSKGERLQQWLDCIRLPDHFHEKWHC 630
               :...|...|:.:.:  ...:|||        ..:|.:..|...|.|.|.::........||.
Mosquito   485 LPSSQLQDAGVELFVTSNEAEGQDLG--------CGVGLREGGSGTQHWQDLMQNNRKPIAMWHV 541

  Fly   631 L 631
            |
Mosquito   542 L 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rph	NP_572651.1	FYVE_like_SF	84..172	CDD:333710	18/74 (24%)
		C2A_Rabphilin_Doc2	354..477	CDD:176000	35/126 (28%)
		C2B_Rabphilin_Doc2	499..631	CDD:176030	42/139 (30%)
LOC1272553	XP_061513620.1	None