Protein Alignment Rph and LOC1270399

DIOPT Version :10

• Sequence 1: NP_572651.1
• Gene: Rph / 32002
• FlyBaseID: FBgn0030230
• Length: 638
• Species: Drosophila melanogaster
• Sequence 2: XP_061505692.1
• Gene: LOC1270399 / 1270399
• VectorBaseID: AGAMI1_010520
• Length: 4490
• Species: Anopheles gambiae
• Alignment Length: 569
• Identity: 135/569 - (23%)
• Similarity: 218/569 - (38%)
• Gaps: 169/569 - (29%)

  Fly   158 PKYDMPRSASATPIPNPGPGSMAGDTRAVQSCHATPTRPARVKKLTIRVNDSSSS-----SSGHS 217
            |.::.|.||....:..||          :|..:....|..|:::|:   |:.|.|     |:|..
Mosquito  3989 PGFNRPPSAPKRAMSAPG----------LQPPYPRRERRNRMQQLS---NEESHSPELTGSTGAL 4040

  Fly   218 EPEDEVDTGVGIGVGVVGGG---MAKGIASTRLQREDSFRLRAYGSIRSFIDGGERKLSNSFFFN 279
            ..||: ..|.|......|.|   ...|.||..:|.:.       |||.|...|.....|:::
Mosquito  4041 GTEDD-PHGSGGSRSAAGDGYDRQGDGTASNGMQHKG-------GSIVSSPVGSAGGASDNW--- 4094

  Fly   280 RQQSQRPSECPEYDSVSMSKLRRESSFLRRGSVSSSWSISDS-----SGSGSNNSGNSQTQSQYQ 339
                  ||:..| |...:..|.:     .|.|:||....|||     ||:|....|....:.|
Mosquito  4095 ------PSQSDE-DIDRLVALHQ-----NRASLSSLGVRSDSMASVYSGAGEGRYGTVTVRGQ-- 4145

  Fly   340 QHQQQLQQHCRDPLLGWLEIAISYREAFHSLDCTMVRARDLPAMDA-AGLADPYCKLNIITPEAH 403
                             :|..:.|.....:|:..:.:.:||.|:|. ...:|||.|:.:: |:..
Mosquito  4146 -----------------IEFGMQYNYKQGALEIHVKQCKDLAAVDTKRNRSDPYVKVYLL-PDKS 4192

  Fly   404 TKYTRWQRTKTVHKTRNPEFNETLQFVGVEPEELGNSLIYVALFDDDKYG-HDFLGAAKVCLSTV 467
            ....|  :||....|.||.|:|.|:| .:....|....|::.::..|.:| :||||
Mosquito  4193 KSGKR--KTKVKKHTLNPVFDEVLRF-HMSLNSLQTRTIWITVWHSDMFGRNDFLG--------- 4245

  Fly   468 HSTSQYRISVPLGVED--------QYSNAAEMAQNWPN-----GKMLLSLCY------------- 506
                    .|.:|::|        |:....|.::.:.:     |.:::.|.|
Mosquito  4246 --------EVMMGLQDKVFDNPQPQWYQLQERSEPFEDLSAYKGDIIVGLKYVSADADGGGIMGA 4302

  Fly   507 ------------------------NTK--------------RRALVVNVKQCINLMAMDNNGSSD 533
                                    :|:              :.||.|.||:..:|..:.:||:.|
Mosquito  4303 GSGVIGGSGGSTSSGFGTLNLRKFSTRSLTSNSSSTLSGHSKGALHVLVKEAKHLQPIKSNGTCD 4367

  Fly   534 PFVKIQLKPDAHKNKKHKTSVKWRTLNPIYNEEFYFE-ASPHDLNKEMLILTVWDKDLGKSNDFL 597
            .|.|..|.||.:::.|.||.|..||.:|::|..|.:| .|..:|::..|.||:||.|...||:||
Mosquito  4368 AFCKSYLLPDKNRSSKQKTPVIKRTNSPVWNYTFVYEDVSLAELSERALELTIWDHDRLASNEFL 4432

  Fly   598 GSLQ--LG-----------AQSKGERLQQWLDCIRLPDHFHEKWHCLAP 633
            |.::  ||           ..|.|:.|..|.:.|..|:.:.|....|.|
Mosquito  4433 GGVRFSLGNGKHNGRAVEWMDSTGKELSLWQNMINRPNFWVEGALVLRP 4481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rph	NP_572651.1	FYVE_like_SF	84..172	CDD:333710	4/13 (31%)
		C2A_Rabphilin_Doc2	354..477	CDD:176000	30/124 (24%)
		C2B_Rabphilin_Doc2	499..631	CDD:176030	49/196 (25%)
LOC1270399	XP_061505692.1	None