Protein Alignment Rph and syt10

DIOPT Version :10

• Sequence 1: NP_572651.1
• Gene: Rph / 32002
• FlyBaseID: FBgn0030230
• Length: 638
• Species: Drosophila melanogaster
• Sequence 2: XP_031754327.1
• Gene: syt10 / 116409668
• XenbaseID: XB-GENE-29099511
• Length: 537
• Species: Xenopus tropicalis
• Alignment Length: 545
• Identity: 115/545 - (21%)
• Similarity: 171/545 - (31%)
• Gaps: 216/545 - (39%)

  Fly   341 TPTTESTAAPST----------STETPTTKTTIGSTSTISQSCIETECD--------DGWIKTLR 387
            |....:..||||          :.:.|....|..| |..|.|.:|:|..        |...:|::
 Frog   517 TKLRSNLPAPSTKEYHVVVSGDTIKLPDISATYAS-SRFSDSGVESEPSSFATHPNTDLVFETVQ 580

  Fly   388 GNNPQKT------LCMK--------LFSHDTSSYDDASMYCYDSHQAFLT-----------GPDS 427
            |..|..:      |.||        |.:|.|.|....|     ..|:.||           .||.
 Frog   581 GQGPCNSERLFPQLLMKPDYNVKFSLGNHCTESTSAIS-----EIQSSLTSINSLPSDDELSPDE 640

  Fly   428 NDEYDKIMEQALNISDQVSDSQSMILIGLKRTTEC--------------TTDSGEQDQ------- 471
            |.:...:.|..||      ||::::.:|.....:|              ...||..|.
 Frog   641 NSKKSVVPECHLN------DSKTVLNLGTTDLPKCDDTKKSSITLQQQSVVFSGNLDNETVAIHS 699

  Fly   472 -NSICRRPKGFIWQDGLGETSNTLINQHFNDDPGVET------SPDHVRACTGIIIVKGATNNKN 529
             ||..:.|..|::.|   |.:::.:....:..|.::|      |||.....||..|    |.|
 Frog   700 LNSSIKDPLQFVFSD---EETSSDVKSSCSSKPNLDTMCKGFQSPDKSNNSTGTAI----TLN-- 755

  Fly   530 VYSLDCSNGEKSSGEKSKMVVCGKLGKCPATTPSTISTTSGASSSTASVS--------STILSST 586
                            ||::..|        ||..|   ||:.||...||        |.:|:
 Frog   756 ----------------SKLICLG--------TPCVI---SGSISSNTDVSEDRTMKKNSDVLN-- 791

  Fly   587 ATTMVTSTPTTEKSSTTTTSTPTSEATSTTTAMITTTSGTTEN----PTTTDCPTKVCRYGF--- 644
            .|.|.:..||.|..:...||.|.|.:|.      ....|..||    .::||. :..|...:
 Frog   792 LTQMYSEIPTVESETHLGTSDPFSASTD------IVKQGLVENYFGSQSSTDI-SDTCAVSYSNA 849

  Fly   645 -----------------------------HPTIRNGKVWCIRVFFHFVLNYQDGSDYCWNYFHST 680
                                         ...::||              |.:.:||      |.
 Frog   850 LSPQKETSEKEISNLQQEQDKEDEEEEQDQQMVQNG--------------YYEETDY------SA 894

  Fly   681 LSGPADENEYNVLLDQTKTDPSLVQSLTKYTKV---FMVLGAQR----TPACLYESSSAQCEKPS 738
            |.|..:.:       .|..|..:.:.|||..|:   ::..|...    |..|| ...||..|.|.
 Frog   895 LDGTINAH-------YTSRDELMEERLTKSEKINSDYLRDGINMPTVCTSGCL-SFPSAPRESPC 951

  Fly   739 GYQW-----LDNVT----DTTYAFT 754
            ..::     .|.:|    .|:|.||
 Frog   952 NVKYSSKSKFDAITKQPSSTSYNFT 976

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rph	NP_572651.1	FYVE_like_SF	84..172	CDD:333710
		C2A_Rabphilin_Doc2	354..477	CDD:176000	38/177 (21%)
		C2B_Rabphilin_Doc2	499..631	CDD:176030	37/149 (25%)
syt10	XP_031754327.1	C2A_Synaptotagmin-1-5-6-9-10	245..370	CDD:176031
		C2B_Synaptotagmin-3-5-6-9-10	379..512	CDD:176048