Protein Alignment Rph and syt8

DIOPT Version :10

• Sequence 1: NP_572651.1
• Gene: Rph / 32002
• FlyBaseID: FBgn0030230
• Length: 638
• Species: Drosophila melanogaster
• Sequence 2: NP_001352218.1
• Gene: syt8 / 103909874
• ZFINID: ZDB-GENE-060303-4
• Length: 397
• Species: Danio rerio
• Alignment Length: 312
• Identity: 101/312 - (32%)
• Similarity: 158/312 - (50%)
• Gaps: 26/312 - (8%)

  Fly   324 SGSNNSGNSQTQSQYQQHQQQLQQHCRDPLLGWLEIAISYREAFHSLDCTMVRARDLPAMDAAGL 388
            ||:..:...|.:::..::....||.      |.|:.::.:..:...|...:..|..|.|||:.|.
Zfish    83 SGTTTTALVQPETEDTEYSSSDQQR------GKLQYSLEFNASRSELTVGIKEAAALKAMDSGGT 141

  Fly   389 ADPYCKLNIITPEAHTKYTRWQRTKTVHKTRNPEFNETLQFVGVEPEELGNSLIYVALFDDDKYG 453
            :|||.|:.|:..::.|     ..||...||.||.|||..:: .:..:||..|.:.:.::|.:::.
Zfish   142 SDPYVKVYILPNKSKT-----FETKVFRKTLNPVFNENFKY-QIPQKELTESTLVMQVYDFNRFS 200

  Fly   454 -HDFLGAAKVCLSTV---HSTSQYRISVPLGVEDQYSNAAEMAQNWPNGKMLLSLCYNTKRRALV 514
             ||.:|..::.||||   |...::|         ..|.|::..|. ..|::..||.|......|.
Zfish   201 KHDIIGEIRLNLSTVDWNHVIEEWR---------DLSEASKHEQE-HLGEICFSLRYVPTSSKLT 255

  Fly   515 VNVKQCINLMAMDNNGSSDPFVKIQLKPDAHKNKKHKTSVKWRTLNPIYNEEFYFEASPHDLNKE 579
            |.:.:..||..||..|||||:||:||..:..|.||.|||||.|||||.:||.|.|:.|...:.|.
Zfish   256 VIILEAKNLKKMDQVGSSDPYVKVQLILEKKKWKKKKTSVKKRTLNPYFNESFTFDVSFEQIQKV 320

  Fly   580 MLILTVWDKDLGKSNDFLGSLQLGAQSKGERLQQWLDCIRLPDHFHEKWHCL 631
            .|:::|||.|....||.:|.:.||..:.|.:|:.|.|.:..|.....:||.|
Zfish   321 QLVISVWDHDKMSRNDAIGKIYLGCDATGNQLRHWADMLSNPRKPVAQWHTL 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rph	NP_572651.1	FYVE_like_SF	84..172	CDD:333710
		C2A_Rabphilin_Doc2	354..477	CDD:176000	37/126 (29%)
		C2B_Rabphilin_Doc2	499..631	CDD:176030	54/131 (41%)
syt8	NP_001352218.1	C2A_Synaptotagmin-1-5-6-9-10	106..229	CDD:176031	38/143 (27%)
		C2B_Synaptotagmin-1	238..372	CDD:176047	55/133 (41%)