Protein Alignment Rph and rph3aa

DIOPT Version :10

• Sequence 1: NP_572651.1
• Gene: Rph / 32002
• FlyBaseID: FBgn0030230
• Length: 638
• Species: Drosophila melanogaster
• Sequence 2: XP_073770455.1
• Gene: rph3aa / 101886567
• ZFINID: ZDB-GENE-090706-2
• Length: 629
• Species: Danio rerio
• Alignment Length: 648
• Identity: 210/648 - (32%)
• Similarity: 326/648 - (50%)
• Gaps: 117/648 - (18%)

  Fly    35 KTSEPLRPEEQEAIISVIRRNEEIEVAERQRVGRLVERVEKIKQHAVERGPNCCRLCGDTFGILR 99
            :|.| |..||::.|.||:.|.:.:|..|::|:|||..|::.:|:.|...|.:.|.|||..||:..
Zfish    38 ETGE-LTDEEKQIINSVLERAKTMEAMEQERIGRLANRLDSMKRSACGDGYSRCLLCGQQFGLTG 101

  Fly   100 PQRILCEDCRQSVCTKCSVDINIRYHTSERSREIWLCRICSETREMWKKSGAWFFKGLPKYDMPR 164
            ...::|.:|::::||||.|      .:..||..||||:||.|.:||.|:||||||||.|:..:|.
Zfish   102 VSAVVCAECKKNMCTKCGV------QSVCRSGPIWLCKICCEHKEMLKQSGAWFFKGSPQQVLPA 160

  Fly   165 ----------SASATPIPNPGPGSMAGDTRAVQSCHATPTRPARVKKLTIRVNDSSSSSSGHSEP 219
                      |.|.|. .||....        ||...:.|:.|...::|.|....|:.:......
Zfish   161 PLAISNQRELSTSRTS-TNPSANQ--------QSPITSQTKNAESVQVTGREQQISAETMPAKRE 216

  Fly   220 EDEVDTGVGIGVGVVGGGMAKGIASTRLQREDSFRLRAYGSIRSFIDGGERKLSNSFFFNRQ--- 281
            |                   :.:.|.|...||..|.|:  :::|  |......:.|....|:
Zfish   217 E-------------------RSVISQRALEEDGGRHRS--TVQS--DAAMEGQTFSPVVKREVPV 258

  Fly   282 QSQRP-----SECP-EYDSVSMSKLRRESSFLRRGSVSSSWSI-----------SDSSGSGSNNS 329
            ||.||     |..| :.|::|..:.|...:......:.::.|:           .|...:.|.:|
Zfish   259 QSSRPPASSFSTTPIQKDTMSRPEARAPPAMQADARLPAANSVPASRQPPPPTTEDEEDANSYDS 323

  Fly   330 GNSQTQSQYQQHQQQLQQHCRDPLLGWLEIAISYREAFHSLDCTMVRARDLPAMDAAGLADPYCK 394
            .::.|                   ||.||.::.|.|..:.|.|.:::|:.|..||:.||||||.|
Zfish   324 DDATT-------------------LGMLEFSLLYTEEKNELHCNIIKAKGLKPMDSNGLADPYVK 369

  Fly   395 LNIITPEAHTKYTRWQRTKTVHKTRNPEFNETLQFVGVEPEELGNSLIYVALFDDDKYGH-DFLG 458
            |::: |.| :|..: .||||:..|.||.:||||.:.|:..|::....:.:::.|:||:|| :|:|
Zfish   370 LHLL-PGA-SKSNK-LRTKTLRTTLNPVWNETLVYHGITNEDMQKKTLRLSVSDEDKFGHNEFIG 431

  Fly   459 AAKVCLS--TVHSTSQYRI------------------SVPLGVEDQYSNAAEMAQNWPNGKMLLS 503
            ..:|.|.  .::....|.:                  .:.|..|:...:.||     ..|::|:|
Zfish   432 ETRVVLKKLKLNQKKTYNVCLERVIPVRRTAGGGASRGMALYEEELKDDEAE-----ERGRILVS 491

  Fly   504 LCYNTKRRALVVNVKQCINLMAMDNNGSSDPFVKIQLKPDAHKNKKHKTSVKWRTLNPIYNEEFY 568
            |.||:::..|:|.|.:|.:|.|||:||.|||||||.||||..|..|:||.:|.:||||.:||||.
Zfish   492 LTYNSQQGRLIVGVVRCAHLAAMDSNGYSDPFVKICLKPDMGKKAKYKTQIKKKTLNPEFNEEFS 556

  Fly   569 FEASPHDLNKEMLILTVWDKDLGKSNDFLGSLQLGAQSKGERLQQWLDCIRLPDHFHEKWHCL 631
            :|....:|.|:.|.::|||.|:||||||:|..|||..:|||.|:.|.:|::..|...|:||.|
Zfish   557 YEIKHGELAKKTLDVSVWDYDMGKSNDFIGGCQLGITAKGECLKHWYECLKNKDKKIERWHVL 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rph	NP_572651.1	FYVE_like_SF	84..172	CDD:333710	39/97 (40%)
		C2A_Rabphilin_Doc2	354..477	CDD:176000	46/143 (32%)
		C2B_Rabphilin_Doc2	499..631	CDD:176030	67/131 (51%)
rph3aa	XP_073770455.1	None