DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rph and LOC100497338

DIOPT Version :9

Sequence 1:	NP_572651.1	Gene:	Rph / 32002	FlyBaseID:	FBgn0030230	Length:	638	Species:	Drosophila melanogaster
Sequence 2:	XP_002938753.2	Gene:	LOC100497338 / 100497338	-ID:	-	Length:	398	Species:	Xenopus tropicalis

Alignment Length:	400	Identity:	89/400 - (22%)
Similarity:	156/400 - (39%)	Gaps:	72/400 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   255 LRAYGSI----RSFIDGG--ERKLSNSFFFNRQQSQRPS----ECPEYDSVSMSKLRRESSFLRR 309
            ||...|:    ::::||.  |:|.:::...   :|..|:    ...|.|| .:..:|:|...|..
Frog    46 LRYKSSVARNEKTYLDGTYVEKKTTSNILL---KSVAPTFLEITRKEQDS-KIQLMRKEMEKLEE 106

  Fly   310 GSVSSSWSISDSSGSGSNNSGNSQTQSQYQQHQQQLQQHCRDPLL--GWLEIAISYREAFHSLDC 372
            ....|..|........||                       .||:  |.|::::.|.:...:|..
Frog   107 RLTPSPPSTESLDDLDSN-----------------------PPLMPRGKLKLSLYYDKKKMALLI 148

  Fly   373 TMVRARDLPAMDAAGLADPYCKLNIIT------PEAHTKYTRWQRTKTVHKTRNPEFNETLQFVG 431
            .::.|.||||..    .||:.::.:.:      ....|....|. ||.|..:|||.|.|:.....
Frog   149 NVIEATDLPAHS----HDPFVRIKVFSKADDPHSSVQTIIHEWD-TKVVKNSRNPVFVESFTCTL 208

  Fly   432 VEPEELGNSLIYVALFDDDKYG-HDFLGAAKVCLSTVHSTSQYRISVPLGVEDQYSNAAEMAQNW 495
            .|.:.|..||.: .:.|.|||. |..:|..:..|..:.::....:         |.:..|..::
Frog   209 KESQLLSTSLKF-EVKDFDKYSRHTLIGETRATLQGLKTSKTLEL---------YEDLQEKTKD- 262

  Fly   496 PNGKMLLSL-CYNTKRRALVVNVKQCINLMAMDNNGSSDPFVKIQLKPDAHKNKKHKTSVKWRTL 559
            ..|::|:|| |..|.::..|..:|  ....::......|.:.:|.:..:.||.|..|:|::.::.
Frog   263 AIGEVLISLKCLPTAQKIEVGILK--FKTSSLSTISERDVYARIDVFTNQHKQKHQKSSLRAKSK 325

  Fly   560 NPIYNEEFYFEASPHDLNKEMLILTVWDKDLGKSNDFLGSLQLGAQSKGERLQQW---LDCIRLP 621
            ..::||.|.| ..|.......|||....:.:......:|...||.|:.......|   :..:|.|
Frog   326 VTVFNETFLF-GLPDPGKTHCLILVSLYETIASGRKLIGQTSLGNQNTKAEDGHWELMMQTLRQP 389

  Fly   622 DHFHEKWHCL 631
               ..|||.|
Frog   390 ---VAKWHPL 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rph	NP_572651.1	PHD_SF	84..172	CDD:304600
		C2A_Rabphilin_Doc2	354..477	CDD:176000	32/131 (24%)
		C2B_Rabphilin_Doc2	499..631	CDD:176030	32/135 (24%)
LOC100497338	XP_002938753.2	C2	129..258	CDD:417471	33/143 (23%)
LOC100497338	XP_002938753.2	C2	265..396	CDD:417471	33/136 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000025
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910