Protein Alignment Rph and syt6

DIOPT Version :10

• Sequence 1: NP_572651.1
• Gene: Rph / 32002
• FlyBaseID: FBgn0030230
• Length: 638
• Species: Drosophila melanogaster
• Sequence 2: XP_002935822.2
• Gene: syt6 / 100488667
• XenbaseID: XB-GENE-953252
• Length: 528
• Species: Xenopus tropicalis
• Alignment Length: 308
• Identity: 90/308 - (29%)
• Similarity: 153/308 - (49%)
• Gaps: 37/308 - (12%)

  Fly   355 GWLEIAISYREAFHSLDCTMVRARDLPAMDAAGLADPYCKLNIITPEAHTKYTRWQRTKTVHKTR 419
            |.:...:.|.....:|...:::|.||||.|..|.:|||.|:.:: |:...|:    :|:...||.
 Frog   231 GKINFTLKYDYEIETLIVRILKAFDLPAKDFCGSSDPYVKIYLL-PDRKRKF----QTRVHRKTL 290

  Fly   420 NPEFNETLQFVGVEPEELGNSLIYVALFDDDKYG-HDFLGAAKVCLSTVHSTSQYRISVPLGVED 483
            ||.|:|:..| .|..::|.|..:::::||.|::. ||.:|  :|.|..:...|.......:..:.
 Frog   291 NPTFDESFHF-PVPYDDLPNRKLHLSVFDFDRFSRHDMIG--EVILENLFEESDLSRESSIWKDI 352

  Fly   484 QYSNAAEMAQNWPNGKMLLSLCYNTKRRALVVNVKQCINLMAMDNNGSSDPFVKIQLKPDAHKNK 548
            ||:.    .::...|:::.||||......|.:.|.:|.||.|||..|.|||:||:.|..|..:.|
 Frog   353 QYAT----TESVDLGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDGRRLK 413

  Fly   549 KHKTSVKWRTLNPIYNEEFYFEASPHDLNKEMLILTVWDKDLGKSNDFLGSLQLGAQSKGERLQQ 613
            |.||::|..||||.|||...|:..|.::::..|:::|.|.|....|:.:|..::|..::|.....
 Frog   414 KKKTTIKKNTLNPTYNEAIIFDIPPENMDQVSLLISVMDYDRVGHNEIIGVCRVGNSTEGLGRDH 478

  Fly   614 WLDCIRLP----DHFH---------EKWH-----------CLAPDNPA 637
            |.:.:..|    .|:|         ::|.           |.:|..||
 Frog   479 WNEMLAYPRKPITHWHPLVEMKKSFKEWQSHAASFDSQGSCPSPKPPA 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rph	NP_572651.1	FYVE_like_SF	84..172	CDD:333710
		C2A_Rabphilin_Doc2	354..477	CDD:176000	36/122 (30%)
		C2B_Rabphilin_Doc2	499..631	CDD:176030	47/155 (30%)
syt6	XP_002935822.2	COG5038	<90..>331	CDD:227371	33/107 (31%)
		C2A_Synaptotagmin-1-5-6-9-10	229..354	CDD:176031	36/130 (28%)
		C2B_Synaptotagmin-3-5-6-9-10	363..496	CDD:176048	47/132 (36%)