Protein Alignment Rph and syt17

DIOPT Version :10

• Sequence 1: NP_572651.1
• Gene: Rph / 32002
• FlyBaseID: FBgn0030230
• Length: 638
• Species: Drosophila melanogaster
• Sequence 2: NP_001096478.1
• Gene: syt17 / 100125097
• XenbaseID: XB-GENE-949409
• Length: 474
• Species: Xenopus tropicalis
• Alignment Length: 585
• Identity: 130/585 - (22%)
• Similarity: 205/585 - (35%)
• Gaps: 206/585 - (35%)

  Fly   102 RILCEDCRQSVCTKCSVDINIRYHTSERSREI----------WLCRICSETREMWKKSGAWFFKG 156
            |..|.:|.|. |.:||.     ..:||...||          ||....||.:|
 Frog    24 RWTCRNCCQK-CYECSC-----CQSSEDEVEILGPFPAQTPPWLVSNRSEDKE------------ 70

  Fly   157 LPKYDMPRSASATPIPNPGPGSMAGDTRAVQSCHATP--TRPARVKKLTIRVNDSSSSSSGHSEP 219
               .|...:.|..|                    |||  |.|.|      |.:.|.:|.|.:|
 Frog    71 ---GDSDNTTSEPP--------------------ATPQDTSPDR------RRSSSDTSRSTYS-- 104

  Fly   220 EDEVDTGVGIGVGVVGGGMAKGIASTRLQREDSFRLRAYGSIRSFIDGGERKLSNSFFFNRQQSQ 284
                              :.:.|:|.                                    :|:
 Frog   105 ------------------LTRRISSL------------------------------------ESR 115

  Fly   285 RPSECP-------EYDSVSMSKLRRESSFLRRGSVSSS---------WSISDSSGSGSNNSGNSQ 333
            |||. |       |:.::...|...:.:.||:......         :|: |||....::..:.:
 Frog   116 RPSS-PLIDIKPIEFGALGAKKEIVQPTVLRKSYTPEDYFRKFEPRLYSL-DSSNDDVDSLTDDE 178

  Fly   334 TQSQYQQHQQQLQQHCRDPLLGWLEIAISYREAFHSLDCTMVRARDLP--------AMDAAGLAD 390
            ..::||              ||.|..:..|....:.|:..::.|||||        ..|.|. ::
 Frog   179 ILTKYQ--------------LGMLHFSTQYDLLHNYLNVRVIEARDLPPPISYDGSRQDMAH-SN 228

  Fly   391 PYCKLNIITPEAHTKYTRWQRTKTVHKTRNPEFNE----TLQFVGVEPEELGNSLIYVALFDDDK 451
            ||.|:.::..:.::|.|..:|     ||:||.|.|    .:||:     |.....:.:.:.|.||
 Frog   229 PYVKICLLPDQKNSKQTGVKR-----KTQNPVFEERYTFEIQFL-----EAQRRTLLLTIVDFDK 283

  Fly   452 YG-HDFLGAAKVCLSTVHSTSQYRISVPLGVED-------------QYSNAAEMAQNWPNGKMLL 502
            :. |..:|               ::::||...|             ...|..|:      |::||
 Frog   284 FSRHCVIG---------------KVAMPLNEVDLVKGGHWWKAIIPSSQNEVEL------GELLL 327

  Fly   503 SLCYNTKRRALVVNVKQCINLMAMDNNGSSDPFVKIQLKPDAHKNKKHKTSVKWRTLNPIYNEEF 567
            ||.|......|.|::.:...|:..|.:..|||||||||.......|..|||....|::|.|||.|
 Frog   328 SLNYLPSAGRLNVDIIRAKQLLQTDMSQGSDPFVKIQLVHGLKLAKTKKTSCMRGTIDPFYNESF 392

  Fly   568 YFEASPHDLNKEMLILTVWDKDLGKSNDFLGSLQLGAQSKGE-RLQQWLDCIRLPDHFHEKWHCL 631
            .|:....:|....|:.||:..::..||||:|.:.:|..:.|. ....|...:.......|:||.|
 Frog   393 SFKVPQEELENVSLVFTVYGHNMKTSNDFIGRIVIGQYASGSPESNHWRRMLNSNRTAVEQWHSL 457

  Fly   632  631
             Frog   458  457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rph	NP_572651.1	FYVE_like_SF	84..172	CDD:333710	19/79 (24%)
		C2A_Rabphilin_Doc2	354..477	CDD:176000	32/135 (24%)
		C2B_Rabphilin_Doc2	499..631	CDD:176030	44/132 (33%)
syt17	NP_001096478.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	54..112		20/118 (17%)
		C2A_Synaptotagmin-15-17	186..314	CDD:176036	34/153 (22%)
		C2B_Synaptotagmin-17	323..457	CDD:176055	45/133 (34%)