Protein Alignment Rph and syt8

DIOPT Version :10

• Sequence 1: NP_572651.1
• Gene: Rph / 32002
• FlyBaseID: FBgn0030230
• Length: 638
• Species: Drosophila melanogaster
• Sequence 2: XP_012815834.1
• Gene: syt8 / 100037878
• XenbaseID: XB-GENE-978920
• Length: 396
• Species: Xenopus tropicalis
• Alignment Length: 290
• Identity: 89/290 - (30%)
• Similarity: 136/290 - (46%)
• Gaps: 38/290 - (13%)

  Fly   355 GWLEIAISYREAFHSLDCTMVRARDLPAMDAAGLADPYCKLNIITPEAHTKYTRWQRTKTVHKTR 419
            |.::.::.|......|...:.:|..|.|||..|.:|||. :..:|.:...|:    .||...||.
 Frog   107 GRVQYSLEYNFQTEELTVGVKQAAALKAMDLGGTSDPYA-IVYVTNDTRKKF----ETKVNRKTL 166

  Fly   420 NPEFNETLQFVGVEPEELGNSLIYVALFDDDKY-GHDFLGAAKVCLSTVHSTSQYRISVPLGVED 483
            ||.|||:..| .|..||:..:...|.:||.::: .||.:|               .:.:|||
 Frog   167 NPVFNESFVF-KVTQEEVPRTTAVVQIFDFNRFLKHDVIG---------------EMVIPLG--- 212

  Fly   484 QYSNAAEMAQNW----PNGK--------MLLSLCYNTKRRALVVNVKQCINLMAMDNNGSSDPFV 536
             ..|...:.::|    |.||        :..||.|......|.:.:.:..||..||::|.|||:|
 Frog   213 -EVNLQHVIEDWKDLGPAGKTEHEHLGDICFSLRYVPSSGKLTIIILEAKNLKRMDSDGFSDPYV 276

  Fly   537 KIQLKPDAHKNKKHKTSVKWRTLNPIYNEEFYFEASPHDLNKEMLILTVWDKDLGKSNDFLGSLQ 601
            |:.|..:..|.|:.||:||..||.|.:||.|.|:.|...:....||::|||.|....|:.:|.|.
 Frog   277 KVHLALNRKKWKRKKTAVKKSTLKPYFNESFTFDVSLEQMKNLDLIISVWDHDKVGKNEQIGKLF 341

  Fly   602 LGAQSKGERLQQWLDCIRLPDHFHEKWHCL 631
            ||.::.|..|:.|.|.:..|.....:||.|
 Frog   342 LGCRASGNALRHWSDMLAHPRRPIAQWHKL 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rph	NP_572651.1	FYVE_like_SF	84..172	CDD:333710
		C2A_Rabphilin_Doc2	354..477	CDD:176000	33/122 (27%)
		C2B_Rabphilin_Doc2	499..631	CDD:176030	48/139 (35%)
syt8	XP_012815834.1	C2A_Synaptotagmin-1-5-6-9-10	105..228	CDD:176031	38/145 (26%)
		C2B_Synaptotagmin-1	237..372	CDD:176047	48/135 (36%)