DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rph and syt19

DIOPT Version :9

Sequence 1:	NP_572651.1	Gene:	Rph / 32002	FlyBaseID:	FBgn0030230	Length:	638	Species:	Drosophila melanogaster
Sequence 2:	XP_001343313.4	Gene:	syt19 / 100003865	ZFINID:	ZDB-GENE-090602-3	Length:	384	Species:	Danio rerio

Alignment Length:	330	Identity:	71/330 - (21%)
Similarity:	134/330 - (40%)	Gaps:	48/330 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   321 SSGSGSNNSGNSQTQSQYQQHQQQLQQHCRDPLLGWLEIAISYREAFHSLDCTMVRARDLPAMDA 385
            |.||...|.|::...:..:..:::..|       |.|..::.|.:....:..|::.|:||...|.
Zfish    82 SPGSSCTNLGSNLDLASLEDLEEEHIQ-------GSLRFSLFYDQLQSKMVVTVLDAQDLAVRDF 139

  Fly   386 AGLADPYCKLNIITPEAHTK--------YTRWQRTKTVHKTRNPEFNETLQFVGVEPEELGNSLI 442
            :...||:..:.::..|...|        ...|| |:.|..:..|.|.:....:..| :|:....:
Zfish   140 SHSVDPFVWVRLMWAEREDKEKNSMRCLLHEWQ-TRIVKNSCCPVFGDQFSCILAE-DEVSRVTV 202

  Fly   443 YVALFDDDKYG-HDFLGAAKVCLSTVHSTSQYRISVPLGVEDQYSNAAEMAQNW--PN----GKM 500
            ...:.|.|||. |..||..:..|:|:      :||.||          |:.|:.  |.    |:.
Zfish   203 RFEVRDFDKYSRHGVLGETRASLNTL------KISYPL----------ELRQDLQVPRKDIVGEA 251

  Fly   501 LLSLCYNTKRRALVVNVKQCINLMAMDNNGSSDPFVKIQLKPDAHKNKKHKTSVKWRTLNPIYNE 565
            ||||.|....:.|.|.|.: |:.:...|......:.:..:..:..:.:..:|:.|.|....::||
Zfish   252 LLSLKYMPTSQRLEVGVLK-IHTVCYHNKTERALYARTIVTCNQSRLRHQRTTQKKRREVTVFNE 315

  Fly   566 EFYFEASPHDLNKEMLILTVWDKDLGK--SNDFLGSLQLGAQSKG--ERLQQWLDCIRLPDHFHE 626
            ...|......:.:..:.::|::....|  |.:.:|.:|:.....|  |..:|.:..:|.|   ..
Zfish   316 VMTFVLPDQQIKECSIEVSVYEIQPSKKSSKNLIGHIQVKKNKTGENEHWKQMMQSLRQP---VA 377

  Fly   627 KWHCL 631
            .||.:
Zfish   378 NWHLI 382

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rph	NP_572651.1	PHD_SF	84..172	CDD:304600
		C2A_Rabphilin_Doc2	354..477	CDD:176000	30/131 (23%)
		C2B_Rabphilin_Doc2	499..631	CDD:176030	28/135 (21%)
syt19	XP_001343313.4	C2	109..241	CDD:301316	35/149 (23%)
syt19	XP_001343313.4	C2	249..382	CDD:301316	29/136 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000025
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000