Protein Alignment Rph and syt3

DIOPT Version :10

• Sequence 1: NP_572651.1
• Gene: Rph / 32002
• FlyBaseID: FBgn0030230
• Length: 638
• Species: Drosophila melanogaster
• Sequence 2: XP_005164031.1
• Gene: syt3 / 100000615
• ZFINID: ZDB-GENE-090601-1
• Length: 566
• Species: Danio rerio
• Alignment Length: 469
• Identity: 124/469 - (26%)
• Similarity: 192/469 - (40%)
• Gaps: 92/469 - (19%)

  Fly   228 GIGVGVVGGGMAKGIASTRLQREDSFRLRAYGSIRSFIDGGERKLSNSFFFN-RQQSQR------ 285
            |.|:|.||||....:....|||:|:..                  |:|.:.. .||.|.
Zfish   101 GAGLGGVGGGGGASLLPPLLQRKDTHS------------------SSSLYPTLSQQGQHHPHFSD 147

  Fly   286 ------------------PSECPEYDSVSMSKLRRESSFLRRGSVSSSWSISDSSGSGSNNSGNS 332
                              |.|..|:..:.|......::.|:....|.....:...||.:.:..|:
Zfish   148 VMGVEGGGGLVVGGVVGGPQEMQEHSYLDMDSYPNNAATLKLSQTSPELPPATEGGSAAKDLPNA 212

  Fly   333 QTQSQYQQHQQQLQQHCRDP------------LLGWL----------------------EIAISY 363
            .:|.|.....:.:......|            .:|.:                      :|:...
Zfish   213 HSQQQVTTRPKPMTHQLSSPDFHGEEKSEQLTSIGQIKPELYRLRQGDQGDGKQGNNCGKISFLL 277

  Fly   364 REAFHS--LDCTMVRARDLPAMDAAGLADPYCKLNIITPEAHTKYTRWQRTKTVHKTRNPEFNET 426
            |.||::  |...:::|.||||.||.|.:|||.|:.:: |:...|:    :||...||.||.||||
Zfish   278 RYAFNTEQLVVKILKALDLPAKDANGFSDPYVKIYLL-PDRKKKF----QTKVHRKTLNPVFNET 337

  Fly   427 LQFVGVEPEELGNSLIYVALFDDDKYG-HDFLGAAKVCLSTVHSTSQYRISVPLGVEDQYSNAAE 490
            .|| ||...||....::.:::|.|::. ||.:|  :|.:..:...|:.....|:. .|.....||
Zfish   338 FQF-GVPLAELHARKLHFSVYDFDRFSRHDLIG--QVVVDNLLDFSEGTGEKPIW-RDIVEGTAE 398

  Fly   491 MAQNWPNGKMLLSLCYNTKRRALVVNVKQCINLMAMDNNGSSDPFVKIQLKPDAHKNKKHKTSVK 555
            .|.   .|::..||||......|.|.:.:..||.|||..|.|||:||..|..:..:.||.|||:|
Zfish   399 KAD---LGELNFSLCYLPTAGRLTVTIIKATNLKAMDLTGFSDPYVKASLVCEGRRLKKRKTSIK 460

  Fly   556 WRTLNPIYNEEFYFEASPHDLNKEMLILTVWDKDLGKSNDFLGSLQLGAQSKGERLQQWLDCIRL 620
            ..||||.|||...|:....::....||:.|.|.|....|:.:|..::|:.:.|...:.|...:..
Zfish   461 KNTLNPTYNEALVFDIPNENIESVSLIIAVMDYDCIGHNEVIGMCRMGSDADGPGREHWTAMLAN 525

  Fly   621 PDHFHEKWHCLAPD 634
            |....|.||.|..:
Zfish   526 PRKPIEHWHQLVEE 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rph	NP_572651.1	FYVE_like_SF	84..172	CDD:333710
		C2A_Rabphilin_Doc2	354..477	CDD:176000	43/147 (29%)
		C2B_Rabphilin_Doc2	499..631	CDD:176030	46/131 (35%)
syt3	XP_005164031.1	C2A_Synaptotagmin-1-5-6-9-10	269..394	CDD:176031	44/133 (33%)
		C2B_Synaptotagmin-3-5-6-9-10	403..536	CDD:176048	47/132 (36%)