Protein Alignment Atg8a and GABARAP

DIOPT Version :9

• Sequence 1: NP_727447.1
• Gene: Atg8a / 32001
• FlyBaseID: FBgn0052672
• Length: 121
• Species: Drosophila melanogaster
• Sequence 2: NP_009209.1
• Gene: GABARAP / 11337
• HGNCID: 4067
• Length: 117
• Species: Homo sapiens
• Alignment Length: 117
• Identity: 107/117 - (91%)
• Similarity: 113/117 - (96%)
• Gaps: 0/117 - (0%)

  Fly     1 MKFQYKEEHAFEKRRAEGDKIRRKYPDRVPVIVEKAPKARIGDLDKKKYLVPSDLTVGQFYFLIR 65
            |||.|||||.|||||:||:|||:||||||||||||||||||||||||||||||||||||||||||
Human     1 MKFVYKEEHPFEKRRSEGEKIRKKYPDRVPVIVEKAPKARIGDLDKKKYLVPSDLTVGQFYFLIR 65

  Fly    66 KRIHLRPEDALFFFVNNVIPPTSATMGSLYQEHHEEDYFLYIAYSDENVYGM 117
            ||||||.||||||||||||||||||||.|||||||||:|||||||||:|||:
Human    66 KRIHLRAEDALFFFVNNVIPPTSATMGQLYQEHHEEDFFLYIAYSDESVYGL 117

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atg8a	NP_727447.1	GABARAP	5..116	CDD:176355	102/110 (93%)
GABARAP	NP_009209.1	Interaction with beta-tubulin. /evidence=ECO:0000269|PubMed:9892355	1..22		16/20 (80%)
		Ubl_ATG8_GABARAP	2..116	CDD:340752	104/113 (92%)
		Interaction with GPHN. /evidence=ECO:0000250|UniProtKB:Q9DCD6	36..117		76/80 (95%)
		Interaction with GABRG2. /evidence=ECO:0000269|PubMed:9892355	36..68		31/31 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	204	1.000	Domainoid score	I2960
eggNOG	1	0.900	-	-		E1_KOG1654
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	225	1.000	Inparanoid score	I3517
Isobase	1	0.950	-	0	Normalized mean entropy	S125
OMA	1	1.010	-	-		QHG54038
OrthoDB	1	1.010	-	-		D1508198at2759
OrthoFinder	1	1.000	-	-		FOG0000590
OrthoInspector	1	1.000	-	-		oto89035
orthoMCL	1	0.900	-	-		OOG6_100707
Panther	1	1.100	-	-	LDO	PTHR10969
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2039
SonicParanoid	1	1.000	-	-		X355
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.820