DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment BTBD9 and btbd11a

DIOPT Version :9

Sequence 1:	NP_001259431.1	Gene:	BTBD9 / 32000	FlyBaseID:	FBgn0030228	Length:	722	Species:	Drosophila melanogaster
Sequence 2:	NP_001314771.1	Gene:	btbd11a / 562893	ZFINID:	ZDB-GENE-050419-142	Length:	1021	Species:	Danio rerio

Alignment Length:	235	Identity:	49/235 - (20%)
Similarity:	92/235 - (39%)	Gaps:	57/235 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 NEQYADVEFIVEEERIPAHRVILAARSEYFRALLYG-GMAETTQRQIPLEVPLEAFKVLLRYIYS 105
            |::.:||.|:||.:...||:|:|...|..|::||.. ..||.|..:|. .|....|:::::|:|.
Zfish   832 NKEMSDVTFLVEGKPFYAHKVLLFTASPRFKSLLSNRPAAENTCIEIS-HVKYNIFQLVMQYLYC 895

  Fly   106 GTLLLSTLDEDSTIDVLGMANQYGFQDLEMAISNYLRQYLALDNVCMILDAARLYNLEELTEVCL 170
            |                      |.:.|          ::....:..:|.||:.:.|:.|...|.
Zfish   896 G----------------------GTESL----------HIRNTEIMELLSAAKFFQLDALQRHCE 928

  Fly   171 MFMDRNAGDLLLHNSFNTLSKESLEEVLRRDCFFAPEVQIFLAVWKWSRFNSNVDFKSVVSYVRL 235
            :...:|            ::.:|..::.:.        ..||...:.:.|......|::|..:.|
Zfish   929 IICSKN------------ITNDSCVDIYKH--------ARFLGALELAGFIEGFFLKNMVLLIEL 973

  Fly   236 PLMNLEHLLQVVRPSGILDPDKILDAIDERSTSKALPYRA 275
            .  |.:.||..| |:....|....|.:.:...:.||..|:
Zfish   974 E--NFKQLLYEV-PADSPGPGPSYDVLHDLEQTLALRIRS 1010

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
BTBD9	NP_001259431.1	BTB	42..141	CDD:279045	25/99 (25%)
		BTB	47..145	CDD:197585	24/98 (24%)
		BACK_BTBD9_like	145..203	CDD:269811	8/57 (14%)
		F5_F8_type_C	299..399	CDD:304887
		F5_F8_type_C	451..554	CDD:279139
btbd11a	NP_001314771.1	H2A	190..276	CDD:305064
		ANK	510..663	CDD:238125
		ANK 1. /evidence=ECO:0000255	515..544
		ANK repeat	518..559	CDD:293786
		Ank_2	520..628	CDD:289560
		ANK repeat	561..594	CDD:293786
		ANK 2. /evidence=ECO:0000255	561..590
		ANK repeat	596..624	CDD:293786
		ANK 3. /evidence=ECO:0000255	599..628
		ANK 4. /evidence=ECO:0000255	642..671
		BTB	828..931	CDD:279045	31/131 (24%)
		BTB	837..935	CDD:197585	31/142 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576659
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930