DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment BTBD9 and btbd6b

DIOPT Version :9

Sequence 1:	NP_001259431.1	Gene:	BTBD9 / 32000	FlyBaseID:	FBgn0030228	Length:	722	Species:	Drosophila melanogaster
Sequence 2:	XP_005160551.1	Gene:	btbd6b / 553533	ZFINID:	ZDB-GENE-030829-65	Length:	535	Species:	Danio rerio

Alignment Length:	353	Identity:	89/353 - (25%)
Similarity:	148/353 - (41%)	Gaps:	48/353 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 NEQYADVEFIV----EEERIPAHRVILAARSEYFRALLYGGMAE-TTQRQIPLEVPLEAFKVLLR 101
            ||..|||.|:|    ..:::|||:.:||..|..|.|:.||.:|| .::..|| :|...||.:||:
Zfish   129 NELMADVHFVVGPPGASQKVPAHKYVLAVGSSVFGAMFYGDLAEGESEIHIP-DVEPAAFLILLK 192

  Fly   102 YIYSGTLLLSTLDEDSTIDVLGMANQYGFQDLEMAISNYLRQYLALDNVCMILDAARLYNLEELT 166
            |:||..:   .|:.|:.:..|..|.:|....|..|...:|...|...|.|::|..:||:...|||
Zfish   193 YMYSDEI---ELEADTVLATLYAAKKYIVPALAKACVTFLETSLEAKNACVLLSQSRLFEEPELT 254

  Fly   167 EVCLMFMDRNAGDLLLHN-SFNTLSKESLEEVLRRDCFFAPEVQIFLAVWKW------------S 218
            ..|...:|..| :|.||: .|..:..::||.:|:|:.....|..:|.|...|            :
Zfish   255 LRCWEVIDAQA-ELALHSEGFCEIDLQTLEIILKRETLNTREAVVFQAALDWAVAECKRQGLGPT 318

  Fly   219 RFNSNVDFKSVVSYVRLPLMNLEHLLQVVRPSGILDPDKILD------AIDERSTSKALPYRAAL 277
            ..|........:..||:|.|.||........|.:|..::..|      |.::......|..|..|
Zfish   319 ARNKRAVLGKALYLVRIPTMTLEEFANGAAQSDVLTLEETHDVFLWYTAANKPKLEFPLQKRKGL 383

  Fly   278 WPE-----ENVAAET----FLSRC--IQGECRDALLDGDVTTYDMENGYTRHCI-TDSKDAGIVV 330
            .|:     ::.|..:    :..||  ||......:....:..|....|...:.: .:.|..|:.
Zfish   384 TPQRCHRFQSSAYRSNQWRYRGRCDSIQFAVDKRIFIAGLGLYGSSGGKAEYSVKIELKRQGVT- 447

  Fly   331 ELGTFCMINHIRMLLWDRDSRAYSYYVE 358
                  :..::...:.|..|..:|.:.|
Zfish   448 ------LAQNLTKFISDGSSNTFSVWFE 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
BTBD9	NP_001259431.1	BTB	42..141	CDD:279045	36/103 (35%)
		BTB	47..145	CDD:197585	34/102 (33%)
		BACK_BTBD9_like	145..203	CDD:269811	20/58 (34%)
		F5_F8_type_C	299..399	CDD:304887	8/61 (13%)
		F5_F8_type_C	451..554	CDD:279139
btbd6b	XP_005160551.1	BTB	126..229	CDD:279045	36/103 (35%)
		BTB	134..233	CDD:197585	34/102 (33%)
		BACK	239..345	CDD:197943	29/106 (27%)
		PHR	390..533	CDD:285277	13/87 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576623
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840