DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment BTBD9 and ABTB2

DIOPT Version :9

Sequence 1:	NP_001259431.1	Gene:	BTBD9 / 32000	FlyBaseID:	FBgn0030228	Length:	722	Species:	Drosophila melanogaster
Sequence 2:	NP_665803.2	Gene:	ABTB2 / 25841	HGNCID:	23842	Length:	1025	Species:	Homo sapiens

Alignment Length:	151	Identity:	33/151 - (21%)
Similarity:	69/151 - (45%)	Gaps:	3/151 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 NEQYADVEFIVEEERIPAHRVILAARSEYFRALLYGGMAETTQRQIPLEV---PLEAFKVLLRYI 103
            |::.:||.|:||.:...||:|:|...|..|:.|:.....:.......:|:   ....|:::::|:
Human   841 NKEMSDVTFLVEGKLFYAHKVLLVTASNRFKTLMTNKSEQDGDSSKTIEISDMKYHIFQMMMQYL 905

  Fly   104 YSGTLLLSTLDEDSTIDVLGMANQYGFQDLEMAISNYLRQYLALDNVCMILDAARLYNLEELTEV 168
            |.|......:.....:::|..|:.:....|:........|.|::::.......|:::|..||...
Human   906 YYGGTESMEIPTTDILELLSAASLFQLDALQRHCEILCSQTLSMESAVNTYKYAKIHNAPELALF 970

  Fly   169 CLMFMDRNAGDLLLHNSFNTL 189
            |..|..::...||..::|..|
Human   971 CEGFFLKHMKALLEQDAFRQL 991

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
BTBD9	NP_001259431.1	BTB	42..141	CDD:279045	21/101 (21%)
		BTB	47..145	CDD:197585	21/100 (21%)
		BACK_BTBD9_like	145..203	CDD:269811	11/45 (24%)
		F5_F8_type_C	299..399	CDD:304887
		F5_F8_type_C	451..554	CDD:279139
ABTB2	NP_665803.2	H2A	194..>242	CDD:305064
		Ank_4	<498..542	CDD:290365
		ANK	516..670	CDD:238125
		ANK 1	521..550
		ANK repeat	524..565	CDD:293786
		Ank_2	526..633	CDD:289560
		ANK repeat	567..604	CDD:293786
		ANK 2	567..596
		ANK 3	606..635
		ANK repeat	606..631	CDD:293786
		ANK repeat	649..679	CDD:293786
		ANK 4	649..678
		BTB	837..940	CDD:279045	21/98 (21%)
		BTB	846..947	CDD:197585	21/100 (21%)
		SPOP_C_like	947..>991	CDD:269810	10/43 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143713
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840