DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment BTBD9 and btbd6a

DIOPT Version :9

Sequence 1:	NP_001259431.1	Gene:	BTBD9 / 32000	FlyBaseID:	FBgn0030228	Length:	722	Species:	Drosophila melanogaster
Sequence 2:	NP_001108397.1	Gene:	btbd6a / 100141360	ZFINID:	ZDB-GENE-080218-26	Length:	525	Species:	Danio rerio

Alignment Length:	276	Identity:	85/276 - (30%)
Similarity:	124/276 - (44%)	Gaps:	41/276 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 NEQYADVEFIV----EEERIPAHRVILAARSEYFRALLYGGMAE-TTQRQIPLEVPLEAFKVLLR 101
            |||.|||.|||    |.:|:|||:.:||..|..|.|:.||.:|| .:...|| :|...||.:||:
Zfish   119 NEQMADVHFIVGPPGESQRVPAHKYVLAVGSSVFCAMFYGDLAEGDSDIHIP-DVEPAAFLILLK 182

  Fly   102 YIYSGTLLLSTLDEDSTIDVLGMANQYGFQDLEMAISNYLRQYLALDNVCMILDAARLYNLEELT 166
            |:||..:.|:   .|:.:..|..|.:|....|..|...:|...|...|.|::|..:||:...|||
Zfish   183 YMYSDEIELA---PDTVLATLYAAKKYLVSALARACVGFLETSLEARNACVLLSQSRLFEEPELT 244

  Fly   167 EVCLMFMDRNAGDLLLHNSFNTLSKESLEEVLRRDCFFAPEVQIFLAVWKWSRFN--------SN 223
            :.|...:|..|...|....|:.:...:||.:|.|:.....|..:|.||..|:...        ::
Zfish   245 QRCWEVIDAQAELALRSEGFSEIDLPTLESILHRETLNVKESVVFQAVLGWADAECRRQGLSPTS 309

  Fly   224 VDFKSVVS----YVRLPLMNLEHLLQVVRPSGILDPDKILDAIDERSTSKALPYRAALWP----- 279
            .:.:||:.    .||||.|.|:..........||..        |.:.|..|.|.||..|
Zfish   310 QNQRSVLGKALHLVRLPSMTLQEFADGAAQVDILTL--------EETHSIFLWYTAATKPSLGFP 366

  Fly   280 ---EENVAAETFLSRC 292
               .|.:.|:    ||
Zfish   367 VNAREGLTAQ----RC 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
BTBD9	NP_001259431.1	BTB	42..141	CDD:279045	40/103 (39%)
		BTB	47..145	CDD:197585	37/102 (36%)
		BACK_BTBD9_like	145..203	CDD:269811	18/57 (32%)
		F5_F8_type_C	299..399	CDD:304887
		F5_F8_type_C	451..554	CDD:279139
btbd6a	NP_001108397.1	BTB	116..219	CDD:279045	40/103 (39%)
		BTB	124..223	CDD:197585	37/102 (36%)
		BACK	229..335	CDD:197943	29/105 (28%)
		PHR	380..523	CDD:285277
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576624
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840