DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment BTBD9 and spop

DIOPT Version :9

Sequence 1:	NP_001259431.1	Gene:	BTBD9 / 32000	FlyBaseID:	FBgn0030228	Length:	722	Species:	Drosophila melanogaster
Sequence 2:	NP_957424.1	Gene:	spop / 100005514	ZFINID:	ZDB-GENE-040426-1378	Length:	374	Species:	Danio rerio

Alignment Length:	197	Identity:	49/197 - (24%)
Similarity:	99/197 - (50%)	Gaps:	13/197 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 QDYTDVVDLGD-RFSADMARLCMNEQYADVEFIVEEERIPAHRVILAARSEYFRALLYGGMAETT 83
            |:..::|.:.| |.:.::..|..:.::.|....|..:...||:.||||||..|.|:....|.|:.
Zfish   173 QNTMNMVKVPDCRLADELGGLWEHSRFTDCSLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESK 237

  Fly    84 QRQIPL-EVPLEAFKVLLRYIYSGTLLLSTLDEDSTIDVLGMANQYGFQDLEMAISNYLRQYLAL 147
            :.::.: :|..|.||.::.:||:|.  ...||:.:. |:|..|::|..:.|::...:.|...|::
Zfish   238 KNRVEINDVEAEVFKEMMFFIYTGK--APNLDKMAD-DLLAAADKYALERLKVMCEDALCTSLSV 299

  Fly   148 DNVCMILDAARLYNLEELTEVCLMFMDRNAGDLLLHNSFNT-------LSKESLEEVLRRDC-FF 204
            :|...||..|.|::.::|....:.|::.:|.|::..:.:.:       |..|:...:....| |.
Zfish   300 ENAAEILILADLHSADQLKTQAVDFINYHASDVMETSGWKSMVASHPHLVAEAYRSLASAQCPFL 364

  Fly   205 AP 206
            .|
Zfish   365 GP 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
BTBD9	NP_001259431.1	BTB	42..141	CDD:279045	28/99 (28%)
		BTB	47..145	CDD:197585	29/98 (30%)
		BACK_BTBD9_like	145..203	CDD:269811	13/65 (20%)
		F5_F8_type_C	299..399	CDD:304887
		F5_F8_type_C	451..554	CDD:279139
spop	NP_957424.1	MATH_SPOP	28..166	CDD:239743
		Required for nuclear localization. /evidence=ECO:0000250	71..191		4/17 (24%)
		BTB_POZ	179..301	CDD:365784	34/124 (27%)
		BACK_SPOP	297..367	CDD:350593	15/70 (21%)
		Homodimerization. /evidence=ECO:0000250	297..355		12/57 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576663
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840