Protein Alignment X11Lbeta and Apba3

DIOPT Version :9

• Sequence 1: NP_727440.3
• Gene: X11Lbeta / 31997
• FlyBaseID: FBgn0052677
• Length: 2139
• Species: Drosophila melanogaster
• Sequence 2: NP_061228.1
• Gene: Apba3 / 57267
• MGIID: 1888527
• Length: 571
• Species: Mus musculus
• Alignment Length: 564
• Identity: 230/564 - (40%)
• Similarity: 312/564 - (55%)
• Gaps: 100/564 - (17%)

  Fly  1657 PALGSPGNGGGSERSAAEMANPGGAVKLSEQEIGT------INGGSVMPLGSGSGTGSGAGSGAG 1715
            |:...|.|    .:||   ..|||.|.|||.|:.|      :.....:|...|.....||.....
Mouse    27 PSENHPSN----TQSA---LGPGGPVTLSEMELDTSSVQELVQQLEALPSDLGGPFPDGAPCPLH 84

  Fly  1716 SGTGTNAAVVANSNANNNVGGGGGG---------------------------------------- 1740
            ..||...|...|.:|...:....||
Mouse    85 IATGQGLATQENPDAGGLLSAEAGGDDLLGLLRDEASSPAQSVPQDPAQTAPRLLQPPEDPDGDP 149

  Fly  1741 ----GNNSSGSGAGSNSNSGEKKVKK------------SKSKE---------------GGAVLIE 1774
                |.::..:.:.|:|:|.|..::.            ::|:|               |...|::
Mouse   150 GWMEGASAEPADSRSSSSSPEPWLETAPLVTQQEPPVGTQSRETLASCPAVTEVPGPCGPEELMD 214

  Fly  1775 GVLFRAKYLGSTQLVCEGQPTKSTRMMQAEEAVSRIKALAPDGDVQPSTEVDLFISTEKIMVLNT 1839
            ||:|.|||||||||:.|..|..||||.||:||:.|:|  ||:|:.||..|||:||||:::.||..
Mouse   215 GVIFGAKYLGSTQLLSERSPAPSTRMGQAQEAMDRVK--APEGETQPMVEVDIFISTKRVKVLAA 277

  Fly  1840 DLKEIMMDHALRTISYIADIGDLVVLMARRRF----VPQDIDDAPKPNRTPKMICHVFESDEAQF 1900
            |.::.:|||||:|||||||||.::|||||||.    .|||     :..|..||:||||.|::||.
Mouse   278 DSQDALMDHALQTISYIADIGPVLVLMARRRLARRTTPQD-----RQRRLYKMLCHVFHSEDAQL 337

  Fly  1901 IAQSIGQAFQVAYMEFLKANGIEDHRFVKEMDYQEVLNSQEIFGDELEIFAKKELQKEVVVPKAK 1965
            |||:|||||.:||.:||:.|.|:.    .::..|....:......:|:.|...:..:||.:.|..
Mouse   338 IAQAIGQAFSIAYSQFLQENRIDP----SQVGTQPSTAASHPHNGDLDHFCNSQNCREVCIQKRP 398

  Fly  1966 GEILGVVIVESGWGSMLPTVVIANLMSSGAAARCGQLNIGDQLIAINGLSLVGLPLSTCQTYIKN 2030
            ||.|||.:|||||||:|||.|||||:..|.|.|||.|:|||::.||||.|||||.|:.||..::.
Mouse   399 GEGLGVALVESGWGSLLPTAVIANLLHGGPAERCGALSIGDRVTAINGTSLVGLSLAACQAAVRE 463

  Fly  2031 TKNQTVVKFTVVPCAPVVEVKIKRPETKYQLGFSVQNGVICSLLRGGIAERGGVRVGHRIIEINN 2095
            .:..:.|..:::.|.||....|:||..:.||||.|::|:||||||||.||||||||||||||:|.
Mouse   464 VRRLSSVTLSIIHCPPVTTAVIRRPHVREQLGFCVEDGIICSLLRGGAAERGGVRVGHRIIEVNG 528

  Fly  2096 QSVVAVPHEKIVNLLATSVGEILMKTMPTSMFRLLTGQENPIYI 2139
            |||||:||.:|:.|| |...||.:||||.:.:|||||||.|:|:
Mouse   529 QSVVAMPHARIIQLL-TETREIHIKTMPAATYRLLTGQEQPVYL 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
X11Lbeta	NP_727440.3	PTB_X11	1770..1924	CDD:269919	88/157 (56%)
		PDZ_signaling	1957..2042	CDD:238492	45/84 (54%)
		PDZ_signaling	2047..2120	CDD:238492	46/72 (64%)
Apba3	NP_061228.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..48		9/27 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	67..195		18/127 (14%)
		PTB_X11	209..361	CDD:269919	88/158 (56%)
		PDZ_signaling	390..475	CDD:238492	45/84 (54%)
		PDZ_signaling	480..548	CDD:238492	44/68 (65%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845950
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3605
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002645
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12345
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2607
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.830