DRSC/TRiP Functional Genomics Resources

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Protein Alignment X11Lbeta and Sdcbp

DIOPT Version :10

Sequence 1:NP_727440.3 Gene:X11Lbeta / 31997 FlyBaseID:FBgn0052677 Length:2139 Species:Drosophila melanogaster
Sequence 2:NP_001091697.1 Gene:Sdcbp / 53378 MGIID:1337026 Length:299 Species:Mus musculus


Alignment Length:301 Identity:61/301 - (20%)
Similarity:129/301 - (42%) Gaps:33/301 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly  1835 MVLNTDLKEIMMDHALRT-ISYIADIGDLVVLMARRRFVPQDIDDA--PKPNRTPKMICHVFESD 1896
            |.|...|:::.:|..::. .:|.|:       .|.:.||..|...|  |..|..||:.     .:
Mouse     1 MSLYPSLEDLKVDKVIQAQTAYSAN-------PASQAFVLVDASAALPPDGNLYPKLY-----PE 53

  Fly  1897 EAQFIAQSIGQAFQVAYMEFLKANGIEDHRFVKEMDYQEVLNSQEIFGDELEIFAKKELQ---KE 1958
            .:|::..|:.:|.....|..:.....:.....:......::  ..:.|::..| .:.|::   :|
Mouse    54 LSQYMGLSLNEAEICESMPMVSGAPAQGQLVARPSSVNYMV--APVTGNDAGI-RRAEIKQGIRE 115

  Fly  1959 VVVPKAKGEILGVVI--VESGWGSMLPTVVIANLMSSGAAARCGQLNIGDQLIAINGLSLVGLPL 2021
            |::.|.:...:|:.:  :::|        :...|:.:.:.|....|..|||::.|||.:..|...
Mouse   116 VILCKDQDGKIGLRLKSIDNG--------IFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSS 172

  Fly  2022 STCQTYIKNTKNQTVVKFTVVPCAPVVEVKIKRPETKYQLGFSVQNGVICSLLRGGIAERGGVRV 2086
            ......:|....:.:.  ..:...|.........::...:||..::|.|.|:::...|.|.|:..
Mouse   173 DKAHKVLKQAFGEKIT--MTIRDRPFERTVTMHKDSSGHVGFIFKSGKITSIVKDSSAARNGLLT 235

  Fly  2087 GHRIIEINNQSVVAVPHEKIVNLLATSVGEILMKTMPTSMF 2127
            .|.|.|||.|:|:.:...:|.::|:|:...:.:..|||.:|
Mouse   236 DHHICEINGQNVIGLKDAQIADILSTAGTVVTITIMPTFIF 276

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
X11LbetaNP_727440.3 PTB_X11 1770..1924 CDD:269919 19/91 (21%)
PDZ1_APBA1_3-like 1957..2042 CDD:467203 16/86 (19%)
PDZ2_APBA1_3-like 2046..2123 CDD:467255 19/76 (25%)
SdcbpNP_001091697.1 Interaction with PDCD6IP. /evidence=ECO:0000269|PubMed:22660413 2..103 19/114 (17%)
LYPX(n)L motif 1. /evidence=ECO:0000305|PubMed:22660413 3..7 1/3 (33%)
LYPX(n)L motif 2. /evidence=ECO:0000305|PubMed:22660413 46..50 1/3 (33%)
LYPX(n)L motif 3. /evidence=ECO:0000305|PubMed:22660413 50..54 0/8 (0%)
PDZ1_syntenin-like 114..192 CDD:467204 16/87 (18%)
PDZ2_syntenin-like 194..271 CDD:467256 19/76 (25%)

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