DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment X11Lbeta and sdcbp

DIOPT Version :9

Sequence 1:	NP_727440.3	Gene:	X11Lbeta / 31997	FlyBaseID:	FBgn0052677	Length:	2139	Species:	Drosophila melanogaster
Sequence 2:	NP_999963.2	Gene:	sdcbp / 407719	ZFINID:	ZDB-GENE-081104-57	Length:	307	Species:	Danio rerio

Alignment Length:	191	Identity:	51/191 - (26%)
Similarity:	92/191 - (48%)	Gaps:	16/191 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly  1942 IFGDELEIFAKKELQ---KEVVVPK-AKGEI-LGVVIVESGWGSMLPTVVIANLMSSGAAARCGQ 2001
            |.|.:|.: .:.|::   :|||:.| ..|:| |.:..:::|        |...|:.:..||....
Zfish   105 ITGSDLGV-KRAEIRQGVREVVLCKDMDGKIGLRLKAIDNG--------VFVQLVQANTAAALAG 160

  Fly  2002 LNIGDQLIAINGLSLVGLPLSTCQTYIKNTKNQTVVKFTVVPCAPVVEVKIKRPETKYQLGFSVQ 2066
            |..|||::.|||.|..|.........:||:..:.:.  ..|...|:........:...||||..:
Zfish   161 LRFGDQILEINGKSCAGWNSDYAHKVLKNSNPERIT--LAVRDRPLERTVTLHKDMNGQLGFIFR 223

  Fly  2067 NGVICSLLRGGIAERGGVRVGHRIIEINNQSVVAVPHEKIVNLLATSVGEILMKTMPTSMF 2127
            .|.|.|:::...:.|.|:...|:|.|||.|:::.:...:|:::|.:|.|.:.:..||..:|
Zfish   224 KGRITSIVKDSSSARNGLLTDHQICEINGQNIIGLKDTQIMDILNSSGGVVTITVMPVVIF 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
X11Lbeta	NP_727440.3	PTB_X11	1770..1924	CDD:269919
		PDZ_signaling	1957..2042	CDD:238492	23/86 (27%)
		PDZ_signaling	2047..2120	CDD:238492	19/72 (26%)
sdcbp	NP_999963.2	PDZ_signaling	121..200	CDD:238492	23/88 (26%)
sdcbp	NP_999963.2	PDZ_signaling	205..278	CDD:238492	19/72 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590658
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840