Protein Alignment X11Lbeta and apba2b

DIOPT Version :9

• Sequence 1: NP_727440.3
• Gene: X11Lbeta / 31997
• FlyBaseID: FBgn0052677
• Length: 2139
• Species: Drosophila melanogaster
• Sequence 2: XP_005168985.1
• Gene: apba2b / 327160
• ZFINID: ZDB-GENE-030131-5371
• Length: 834
• Species: Danio rerio
• Alignment Length: 826
• Identity: 315/826 - (38%)
• Similarity: 405/826 - (49%)
• Gaps: 249/826 - (30%)

  Fly  1440 GSNCSS----SANGGMPPPIPERTNLVSAVQRSPSPGPNSPVWLSRHLDGGAGKDLLESGSDNHS 1500
            |.:|:.    ..:|.|.|| |:......||:.          |:.       |:|  ::..|...
Zfish   132 GMDCNDPEYVHPDGRMEPP-PDTDECQEAVEE----------WVE-------GED--DAQGDEDD 176

  Fly  1501 KNHSADEEDVDTDLETDRLLGHQRLDDQGYYDENKSWDRKPRSLLSK------ISPKQQIPSTKT 1559
            .:...|::|.|.::..:.|  .|..|.|.|       |.:|..:|..      ..|.|:
Zfish   177 DDEEEDDDDDDGEVRCEVL--EQDSDQQLY-------DGRPEPVLDHHHHQHYTDPHQE------ 226

  Fly  1560 RNGYNALLSSTPELPPPI---------------------PPKGQSGLGLG----LTLGAGNGGKL 1599
                        :|||||                     |..|:...|..    .|...||..:.
Zfish   227 ------------QLPPPIEDQEVKDVESSERYCPDQEEEPQVGRDREGYAGDYYATEDNGNSVRA 279

  Fly  1600 LDLVGGMVQRSLSRSSSEHSEKSLS------KMPISGGDLCAGGVDVVASTVAATSATVVASTPA 1658
            ....|   .:.....:.|.:|:.:.      ||.:|.|.|.:|         ...|...:|..||
Zfish   280 SPYRG---HKGTEGETGEEAEEDIDQIVAEIKMSMSMGSLSSG---------TDQSPEELAPDPA 332

  Fly  1659 LGSPGNGGGSERSAAEMA------------------------NP--------------------- 1678
               |.......||..|.|                        ||
Zfish   333 ---PSGYQPETRSKPEPAPAPYPQPHRHDGRPKSLNIPPARHNPELQRNFKVRPHTPEDRQRWTQ 394

  Fly  1679 --------GGAVKLSEQEIGTINGGSVMPLGSGSGTGSGAGSGAGSGTGTNAAVVANSNANNNVG 1735
                    .||.:..:|:...:||    ||                             .||||
Zfish   395 DQVREQMSNGAEQPRKQQRSDLNG----PL-----------------------------ENNNV- 425

  Fly  1736 GGGGGGNNSSGSGAGSNSNSGEKKVKKSKS------------KEGGAVLIEGVLFRAKYLGSTQL 1788
                                 .:..||:.|            .|.   ||:|::|.|.|||||||
Zfish   426 ---------------------TEPTKKTASFPSFVDVPGPCEPED---LIDGIIFAANYLGSTQL 466

  Fly  1789 VCEGQPTKSTRMMQAEEAVSRI-----------KALAPDGDVQPSTEVDLFISTEKIMVLNTDLK 1842
            :.|..|:|:.|||||:|||||:           ||.:|:||.|..|||||||||::|.|||.|.:
Zfish   467 LSERNPSKNIRMMQAQEAVSRVKRVQKAAKIKKKAQSPEGDAQTLTEVDLFISTQRIKVLNADTQ 531

  Fly  1843 EIMMDHALRTISYIADIGDLVVLMARRRF---VPQDIDD----APKPNRTPKMICHVFESDEAQF 1900
            |.|||:||||||||||||::||||||||.   ..||..:    ||:..:..|||||||||::||.
Zfish   532 ETMMDNALRTISYIADIGNIVVLMARRRMPRTASQDCIETTPGAPEAKKQYKMICHVFESEDAQL 596

  Fly  1901 IAQSIGQAFQVAYMEFLKANGI--EDHRFVKEMDYQEVLNSQEIFGDELEIFAKKELQKEVVVPK 1963
            |||||||||.|||.|||:||||  ||   :.:.:|.:::|:||::.|:|..|:..:..||:.:.|
Zfish   597 IAQSIGQAFSVAYQEFLRANGINPED---LSQKEYSDIINTQEMYNDDLIHFSNSDNCKELQLEK 658

  Fly  1964 AKGEILGVVIVESGWGSMLPTVVIANLMSSGAAARCGQLNIGDQLIAINGLSLVGLPLSTCQTYI 2028
            .||||||:|||||||||:||||::||:|:.|.|||.|:|:||||:::||..|||||||:|||..|
Zfish   659 QKGEILGIVIVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINNTSLVGLPLATCQGII 723

  Fly  2029 KNTKNQTVVKFTVVPCAPVVEVKIKRPETKYQLGFSVQNGVICSLLRGGIAERGGVRVGHRIIEI 2093
            |..|||..||..:|.|.||..|.||||:.|||||||||||:||||:|||||||||||||||||||
Zfish   724 KGLKNQVQVKLNIVSCPPVTTVLIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEI 788

  Fly  2094 NNQSVVAVPHEKIVNLLATSVGEILMKTMPTSMFRLLTGQENPIYI 2139
            |.|||||..|||||..|:.|||||.|||||.:|||||||||.|:||
Zfish   789 NGQSVVATAHEKIVQALSNSVGEIHMKTMPAAMFRLLTGQETPMYI 834

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
X11Lbeta	NP_727440.3	PTB_X11	1770..1924	CDD:269919	103/173 (60%)
		PDZ_signaling	1957..2042	CDD:238492	54/84 (64%)
		PDZ_signaling	2047..2120	CDD:238492	57/72 (79%)
apba2b	XP_005168985.1	PTB_X11	447..620	CDD:269919	104/175 (59%)
		PDZ	653..734	CDD:278991	52/80 (65%)
		PDZ	746..817	CDD:278991	57/70 (81%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590660
Domainoid	1	1.000	175	1.000	Domainoid score	I3583
eggNOG	1	0.900	-	-		E1_KOG3605
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	530	1.000	Inparanoid score	I1184
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002645
OrthoInspector	1	1.000	-	-		mtm6563
orthoMCL	1	0.900	-	-		OOG6_104247
Panther	1	1.100	-	-	O	PTHR12345
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2607
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.780