DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment X11Lbeta and Sdcbp2

DIOPT Version :9

Sequence 1:	NP_727440.3	Gene:	X11Lbeta / 31997	FlyBaseID:	FBgn0052677	Length:	2139	Species:	Drosophila melanogaster
Sequence 2:	NP_001020863.1	Gene:	Sdcbp2 / 311532	RGDID:	1307709	Length:	296	Species:	Rattus norvegicus

Alignment Length:	229	Identity:	55/229 - (24%)
Similarity:	96/229 - (41%)	Gaps:	31/229 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly  1937 LNSQEI--------FGDELEIFAKKELQKEVVVPKAKGEILGVVIVE---------------SGW 1978
            |:|||:        .||.:.|.:....|   |.....|..|||:..|               ...
  Rat    62 LSSQEVQKNLSQIPDGDNMVITSPGPGQ---VTAPVSGNDLGVLRAEIKPGVREIHLCKDERGKT 123

  Fly  1979 GSMLPTV---VIANLMSSGAAARCGQLNIGDQLIAINGLSLVGLPLSTCQTYIKNTKNQTVVKFT 2040
            |..|..|   :...|:.:...|....|..|||::.|:|....|......|..:|....:.:|  .
  Rat   124 GLRLQAVDKGLFVQLVQANTPASLVGLRFGDQILQIDGCDCAGWSTHKAQKALKKASAEKIV--M 186

  Fly  2041 VVPCAPVVEVKIKRPETKYQLGFSVQNGVICSLLRGGIAERGGVRVGHRIIEINNQSVVAVPHEK 2105
            ||...|.........::..|:||.::.|.|.|:::|..|.|.|:...|.:.|:|.|:|:.:..:|
  Rat   187 VVRDRPFQRTVTMHKDSSGQVGFFIKKGKIVSVVKGSSAARNGLLTNHYVCEVNGQNVIGLKDKK 251

  Fly  2106 IVNLLATSVGEILMKTMPTSMFRLLTGQENPIYI 2139
            |:.:|.|:...|.:..:||.::..:..:.:|:.:
  Rat   252 IIEILTTAGNVITLTIIPTVIYEHMIKKLSPLLL 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
X11Lbeta	NP_727440.3	PTB_X11	1770..1924	CDD:269919
		PDZ_signaling	1957..2042	CDD:238492	21/102 (21%)
		PDZ_signaling	2047..2120	CDD:238492	20/72 (28%)
Sdcbp2	NP_001020863.1	PDZ_signaling	110..189	CDD:238492	16/80 (20%)
Sdcbp2	NP_001020863.1	PDZ_signaling	195..268	CDD:238492	20/72 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349385
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840