DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment X11Lbeta and Sdcbp2

DIOPT Version :9

Sequence 1:	NP_727440.3	Gene:	X11Lbeta / 31997	FlyBaseID:	FBgn0052677	Length:	2139	Species:	Drosophila melanogaster
Sequence 2:	NP_663510.1	Gene:	Sdcbp2 / 228765	MGIID:	2385156	Length:	292	Species:	Mus musculus

Alignment Length:	235	Identity:	51/235 - (21%)
Similarity:	95/235 - (40%)	Gaps:	43/235 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly  1946 ELEIF-----AKKELQKEV------------------VVPKAKGEILGVVIVE------------ 1975
            |||.:     :.:|:||.:                  ||....|..||::..|
Mouse    49 ELESYMGLSLSSQEVQKNLTQIPDSDNMVVTSPGPGQVVAPVSGNNLGILRAEIKPGVREIHLCK 113

  Fly  1976 ---SGWGSMLPTV---VIANLMSSGAAARCGQLNIGDQLIAINGLSLVGLPLSTCQTYIKNTKNQ 2034
               ...|..|..|   :...|:.:...|....|..|||::.|:|....|.........:|....:
Mouse   114 DERGKTGLRLQAVDKGLFVQLVQANTPASLVGLRFGDQILQIDGCDCAGWNTHKAHKVLKKASAE 178

  Fly  2035 TVVKFTVVPCAPVVEVKIKRPETKYQLGFSVQNGVICSLLRGGIAERGGVRVGHRIIEINNQSVV 2099
            .:|  .|:...|.........::..|:|||::.|.|.|:::|..|.|.|:...|.:.|:|.|:|:
Mouse   179 KIV--MVIRDRPFQRTVTMHKDSSGQVGFSIKKGKIVSVVKGSSAARNGLLTNHYVCEVNGQNVI 241

  Fly  2100 AVPHEKIVNLLATSVGEILMKTMPTSMFRLLTGQENPIYI 2139
            .:..:|:..:|.|:...|.:..:||.::..:..:.:|:.:
Mouse   242 GLKDKKVTEILTTAGDVITLTIIPTVIYEHMIKRLSPLLL 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
X11Lbeta	NP_727440.3	PTB_X11	1770..1924	CDD:269919
		PDZ_signaling	1957..2042	CDD:238492	21/120 (18%)
		PDZ_signaling	2047..2120	CDD:238492	20/72 (28%)
Sdcbp2	NP_663510.1	PDZ	117..185	CDD:238080	15/69 (22%)
Sdcbp2	NP_663510.1	PDZ_signaling	191..264	CDD:238492	20/72 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845953
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840