Protein Alignment X11Lbeta and apba2

DIOPT Version :10

• Sequence 1: NP_727440.3
• Gene: X11Lbeta / 31997
• FlyBaseID: FBgn0052677
• Length: 2139
• Species: Drosophila melanogaster
• Sequence 2: XP_004917984.2
• Gene: apba2 / 100498579
• XenbaseID: XB-GENE-952383
• Length: 749
• Species: Xenopus tropicalis
• Alignment Length: 817
• Identity: 315/817 - (38%)
• Similarity: 417/817 - (51%)
• Gaps: 185/817 - (22%)

  Fly  1439 AGSNCSSSANGGMP------PPIP---ERTNLVSAVQRSPSPGPNSPVWLSRHL----------- 1483
            |...|.|:....|.      ||.|   :..:..|..:....|..||.:..|||:
 Frog     2 ANRKCQSTTASIMDQRPRSCPPSPHAMDPGSEESVYEEVIVPDFNSRISKSRHMSNTQEDHDCND 66

  Fly  1484 ---DGGAGKDLLESGSD---------------------------------------NHSKNHSAD 1506
               ||.:..|.:.:.||                                       :|.::|...
 Frog    67 NSGDGDSSSDYVNNTSDEEYDEGLPDEEEGITYYIRYCPEDDSYLEGMDCNGEEYIHHEEHHIET 131

  Fly  1507 EEDVDT--DLETDRLLGHQRLDDQGYYDENKSWDRKPRSLLSKISPKQQIPSTKTRNGYNALLSS 1569
            :|.|:.  |..|:.....|...|:...:||:.......|.|.:.:..::...::...||....|
 Frog   132 DECVEAVEDEWTESKTQQQHCIDRDTEEENQMITLGQDSSLEEHNQVEEAHFSENEEGYPDYYS- 195

  Fly  1570 TPE-----LPP-PIPPKGQSGLGLGLTLGAGNGGKLLDLVGGMVQRSLSRSSSEHSEKSLSKMPI 1628
             ||     ||| |.|          :..|.||                    :|..|:.:.:
 Frog   196 -PEANGNSLPPSPFP----------IRKGDGN--------------------TEEPEEDIDQ--- 226

  Fly  1629 SGGDLCAGGVDVVASTVAATSATVVAST----PALGSPGNGGGSERSAAEMANPGGAVKLSEQEI 1689
                       :||....:.|.:.:.||    |......|.....:...:..:.|......|...
 Frog   227 -----------IVAEIKMSMSMSSINSTTDTSPEHNVTENVAKDIKEICQKVDSGHCASRHEGRP 280

  Fly  1690 GTINGGSVMPLGSGSGTGSGAGSGAGSGTG-----------TNAAVVANSNANNNVGGGGGGGNN 1743
            .::|    :|..|...|....|..|.|.|.           .|:|........:::.|
 Frog   281 KSLN----IPSASKPATELQRGYKAKSRTPEERQKWVPEQVCNSAEQPRKQQRSDLNG------- 334

  Fly  1744 SSGSGAGSNSNSGEKKVKKSKS------------KEGGAVLIEGVLFRAKYLGSTQLVCEGQPTK 1796
                  ..::|:.:::.||..|            .|.   ||:|::|.|.:||||||:.|..|:|
 Frog   335 ------PVDNNNVQEQTKKVASFPSFVDVPGPCEPED---LIDGIIFAANFLGSTQLLSERNPSK 390

  Fly  1797 STRMMQAEEAVSRIKALA----------PDGDVQPSTEVDLFISTEKIMVLNTDLKEIMMDHALR 1851
            :.|||||:|||||:|.:.          .:||.|..|||||||||::|.|||.|.:|.|||||||
 Frog   391 NIRMMQAQEAVSRVKRMQKAAKIKKKANSEGDSQTLTEVDLFISTQRIKVLNADTQETMMDHALR 455

  Fly  1852 TISYIADIGDLVVLMARRRF---VPQD-IDDAP---KPNRTPKMICHVFESDEAQFIAQSIGQAF 1909
            |||||||||::||||||||.   ..|| |:..|   :..:..|||||||||::||.|||||||||
 Frog   456 TISYIADIGNIVVLMARRRMPRSASQDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAF 520

  Fly  1910 QVAYMEFLKANGI--EDHRFVKEMDYQEVLNSQEIFGDELEIFAKKELQKEVVVPKAKGEILGVV 1972
            .|||.|||:||||  ||   :.:.:|.:::|:||::.|:|..|:.....||:.|.|.||||||||
 Frog   521 SVAYQEFLRANGINPED---LSQKEYSDIINTQEMYNDDLIHFSNSANCKELQVEKLKGEILGVV 582

  Fly  1973 IVESGWGSMLPTVVIANLMSSGAAARCGQLNIGDQLIAINGLSLVGLPLSTCQTYIKNTKNQTVV 2037
            ||||||||:||||::||:|:.|.|||.|:|:||||:::|||.|||||||:|||..||..||||.:
 Frog   583 IVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQL 647

  Fly  2038 KFTVVPCAPVVEVKIKRPETKYQLGFSVQNGVICSLLRGGIAERGGVRVGHRIIEINNQSVVAVP 2102
            |..:|.|.||..|.||||:.|||||||||||:||||:||||||||||||||||||||.|||||..
 Frog   648 KLNIVSCPPVTTVLIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATA 712

  Fly  2103 HEKIVNLLATSVGEILMKTMPTSMFRLLTGQENPIYI 2139
            |||||..|:.|||||.|||||.:|||||||||.|:||
 Frog   713 HEKIVQALSNSVGEIHMKTMPAAMFRLLTGQETPLYI 749

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
X11Lbeta	NP_727440.3	PTB_X11	1770..1924	CDD:269919	101/172 (59%)
		PDZ1_APBA1_3-like	1957..2042	CDD:467203	57/84 (68%)
		PDZ2_APBA1_3-like	2046..2123	CDD:467255	61/76 (80%)
apba2	XP_004917984.2	PTB_X11	363..535	CDD:269919	102/174 (59%)
		PDZ1_APBA1_3-like	567..652	CDD:467203	57/84 (68%)
		PDZ2_APBA1_3-like	656..733	CDD:467255	61/76 (80%)