DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2111 and AT1G63770

DIOPT Version :9

Sequence 1:	NP_572644.1	Gene:	CG2111 / 31995	FlyBaseID:	FBgn0030223	Length:	931	Species:	Drosophila melanogaster
Sequence 2:	NP_001117543.4	Gene:	AT1G63770 / 842681	AraportID:	AT1G63770	Length:	987	Species:	Arabidopsis thaliana

Alignment Length:	937	Identity:	186/937 - (19%)
Similarity:	335/937 - (35%)	Gaps:	240/937 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 VDIVTRINQPYQPFGGTVVIDLRSERSTKRIVLNAHDLAIGKRRAVTLSDK-NGNSVPVSSIQMD 100
            ||:...:.:........:.:..|.:.|:..:||:.|||.:       ||.| .|..:.....|:|
plant   114 VDLSFSLGEEKTIVSSKIKVSPRVKGSSAALVLDGHDLKL-------LSVKVEGKLLKEGDYQLD 171

  Fly   101 IKLSRLTVSLKRPLKVNVTYSMRVAFTSVLRNDNT---GFY--SSNYVDHNTTLTQWLAATQFEP 160
            .:  .||:.   .|....::.:.:. |.:..:.||   |.|  |.|:            .||.|.
plant   172 SR--HLTLP---SLPAEESFVLEID-TEIYPHKNTSLEGLYKSSGNF------------CTQCEA 218

  Fly   161 NHAREAFPCFDDPIFRTPFKINL-AHPYLYRAL---SNMPVQRTI---RHASLKDYVWTQFVESH 218
            ...|:.....|.|.....:...: ....||..|   .|:..|..|   ||.:|    |.   :..
plant   219 EGFRKITFYQDRPDIMAKYTCRVEGDKTLYPVLLSNGNLISQGDIEGGRHYAL----WE---DPF 276

  Fly   219 PMQTYLVAF----MISKFDRPGFTSSERSDCPISTWARPDALSQTEFANMVVAPLLSFYEDLFNS 279
            ....||.|.    ::|:.|.  ||:.......:..|...:.|.:|..|...:...:.:.||:|..
plant   277 KKPCYLFALVAGQLVSRDDT--FTTRSGRQVSLKIWTPAEDLPKTAHAMYSLKAAMKWDEDVFGL 339

  Fly   280 TYRQKKIDLVALPDFTFKSKENWGLPAFAEESLLYDSQRSSIDDQQGVARAVAMMVVNQWFGNLV 344
            .|.....::||:|||...:.||..|..|..:.:|...:.::..|...:...:.....:.|.||.|
plant   340 EYDLDLFNIVAVPDFNMGAMENKSLNIFNSKLVLASPETATDADYAAILGVIGHEYFHNWTGNRV 404

  Fly   345 SVAWWHEIWLKNVFAL-----YLSRFGVHSLRPEWDYQERHALQLYLSVLDY---------DAHV 395
            :...|.::.||....:     :.|..|..:::...|..:   |::|....|.         .:::
plant   405 TCRDWFQLSLKEGLTVFRDQEFSSDMGSRTVKRIADVSK---LRIYQFPQDAGPMAHPVRPHSYI 466

  Fly   396 NTD-LVTASVPDESHIWAAYNEIGERKAAVLFEMLHRVMGEEAWLTALRRYLVVYANRTATSSDF 459
            ..| ..|.:|.::  :|...|.:.....|.:..|...::|.:.:...:..|...:..:..|..||
plant   467 KMDNFYTVTVYEK--VWLFTNSVLLYAGAEVVRMYKTLLGTQGFRKGIDLYFERHDEQAVTCEDF 529

  Fly   460 WDLLQLQVDRNGRLGKGLNITRIMKCWLGQPGYPLVTVTRNY--DHRT-AIVSQQRFFITPQFRN 521
            :..::   |.|     ..:....:: |..|.|.|:|.|..:|  |.|| ::...|....||   .
plant   530 FAAMR---DAN-----NADFANFLQ-WYSQAGTPVVKVVSSYNADARTFSLKFSQEIPPTP---G 582

  Fly   522 RWARNPCWWVPL----------SYTCPSCQHSEIISFSRWLTCPTSKPSSKSNTVLLEKLEAEPT 576
            :..:.|. ::|:          ..|..|..|.           .|.:..|.|:|:|  ::..:..
plant   583 QPTKEPT-FIPVVVGLLDSSGKDITLSSVHHD-----------GTVQTISGSSTIL--RVTKKEE 633

  Fly   577 DWILFNVQH----------TAPFRVNYDLRNWQLLNKTLADPNKFRLIHRVNRAQLVDDLFSLAW 631
            :::..::..          :||.||..||.|                          ||||.|
plant   634 EFVFSDIPERPVPSLFRGFSAPVRVETDLSN--------------------------DDLFFL-- 670

  Fly   632 SGDIEYDMALGILGYLEHE-DEFVVWVATEISFER--INNVAKSNPNYLIFKTYMRLLLERQFKR 693
                           |.|: |||..|.|.::...:  :|.|:.       |:....|.|..:|.:
plant   671 ---------------LAHDSDEFNRWEAGQVLARKLMLNLVSD-------FQQNKPLALNPKFVQ 713

  Fly   694 VISSDLTSSSGNMTHRPVIIRLACEYELPACVSLARREFMKGTPEKGGWMTIRERETVVCTAVKF 758
            .:.|.|:.||.:.......|.|..|.|:...:::|
plant   714 GLGSVLSDSSLDKEFIAKAITLPGEGEIMDMMAVA------------------------------ 748

  Fly   759 GTEGDRDMVESMYK--RSNFAAE-KESLLTALACSRNVFALQRVLIWTFESSGVRKQNARRTFKA 820
                |.|.|.::.|  |...|:| ||.||..:..:|:..|      :.|:.|.:    |||..|
plant   749 ----DPDAVHAVRKFVRKQLASELKEELLKIVENNRSTEA------YVFDHSNM----ARRALK- 798

  Fly   821 VVSNSMGYRLAKK---YVSVNMQNIRNYCSNSTDKVVNLMTPLIECLSTPKELL--YFSK----- 875
              :.::.|..:.:   |:.:.: |.....:|.||:...|.........|..::|  :::|
plant   799 --NTALAYLASLEDPAYMELAL-NEYKMATNLTDQFAALAALSQNPGKTRDDILADFYNKWQDDY 860

  Fly   876 ------FFKEILRDMNGSERLIKILLE 896
                  |..:...|:.|:...:|.||:
plant   861 LVVNKWFLLQSTSDIPGNVENVKKLLD 887

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2111	NP_572644.1	Peptidase_M1	25..421	CDD:279741	85/415 (20%)
		M1_APN_2	33..493	CDD:189008	97/487 (20%)
		ERAP1_C	579..897	CDD:288671	69/350 (20%)
AT1G63770	NP_001117543.4	pepN	92..987	CDD:237585	186/937 (20%)
AT1G63770	NP_001117543.4	M1_APN_1	103..985	CDD:189007	186/937 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	1	1.000	-	-		FOG0000044
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820