DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG2111 and Rnpep

DIOPT Version :9

Sequence 1:NP_572644.1 Gene:CG2111 / 31995 FlyBaseID:FBgn0030223 Length:931 Species:Drosophila melanogaster
Sequence 2:NP_112359.2 Gene:Rnpep / 81761 RGDID:621137 Length:650 Species:Rattus norvegicus


Alignment Length:450 Identity:107/450 - (23%)
Similarity:159/450 - (35%) Gaps:117/450 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   152 WLAA------------TQFEPNHAREAFPCFDDPIFRTPFKINLAHPYLYRALSNMPVQRTIRHA 204
            |||.            ||.:....|..|||||.|..:.          .|.||..:|...|   |
  Rat   152 WLAPEQTAGKKKPFVYTQGQAVLNRAFFPCFDTPAVKC----------TYSALVEVPDGFT---A 203

  Fly   205 SLKDYVWTQ-------FVESHPMQTYLVAFMISKFDRPGFTSSERSDCPISTWARPDAL-SQTEF 261
            .:....|.:       |..:.|:.:||:|..|.  |........||    ..||.|..: :..|.
  Rat   204 VMSASTWERRGPNKFFFQMNQPIPSYLIALAIG--DLASAEVGPRS----RVWAEPCLIEAAKEE 262

  Fly   262 ANMVVAPLLSFYEDLFNSTYRQKKIDLVAL-PDFTFKSKENWGLPAFAEESLLYDSQRSSIDDQQ 325
            .|.|:...|:..|.|| ..|...:.||:.: |.|.|...||..| .|....||...         
  Rat   263 YNGVIEEFLATGEKLF-GPYVWGRYDLLFMPPSFPFGGMENPCL-TFVTPCLLAGD--------- 316

  Fly   326 GVARAVAMMVVNQ----WFGNLVSVAWWHEIWLKNVFALYLSR------FGVHSLRPEWDYQE-- 378
               |::|.:::::    ||||||:.|.|.|.||...|.:|..|      ||.     .:...|  
  Rat   317 ---RSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGA-----AYTCLEAA 373

  Fly   379 --RHALQLYLSVLDYDAHVN---TDLVTASVPDESHIWAAYNEIGERKAAVLFEML-HRVMGEEA 437
              |..|:.::.|...:..:|   ..:.....||::     |||....|.......| |.|..:|.
  Rat   374 TGRALLRQHMDVSGEENPLNKLRVKIEPGVDPDDT-----YNETPYEKGYCFVSYLAHLVGDQEQ 433

  Fly   438 WLTALRRYLVVYANRTATSSDFWDLLQLQVDRNGRLGK-------GLNITRIMKCWLGQPGYPLV 495
            :...|:.|:..:..::..:.||   |:..::....|.|       |....|    ||..||:|..
  Rat   434 FDKFLKAYVDEFKFQSILAEDF---LEFYLEYFPELKKKGVDSIPGFEFNR----WLNTPGWPPY 491

  Fly   496 TVTRNYDHRTAIVSQQRFFITP--QFRNRWARNPCWWVPLSYTCPSCQHSEIISFSRWLT 553
            ...         :|.....:.|  :....||.:.          |..|..|.::.|.|.|
  Rat   492 LPD---------LSPGDSLMKPAEELAELWAASE----------PDMQAIEAVAISTWKT 532

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2111NP_572644.1 Peptidase_M1 25..421 CDD:279741 78/306 (25%)
M1_APN_2 33..493 CDD:189008 96/386 (25%)
ERAP1_C 579..897 CDD:288671
RnpepNP_112359.2 M1_LTA4H 24..484 CDD:341062 93/381 (24%)
Substrate binding. /evidence=ECO:0000250 298..302 0/3 (0%)
Leuk-A4-hydro_C 530..645 CDD:401171 1/2 (50%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166349325
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0308
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.830

Return to query results.
Submit another query.