Protein Alignment CG2111 and Lvrn

DIOPT Version :10

• Sequence 1: NP_572644.1
• Gene: CG2111 / 31995
• FlyBaseID: FBgn0030223
• Length: 931
• Species: Drosophila melanogaster
• Sequence 2: NP_083284.1
• Gene: Lvrn / 74574
• MGIID: 1921824
• Length: 991
• Species: Mus musculus
• Alignment Length: 951
• Identity: 260/951 - (27%)
• Similarity: 421/951 - (44%)
• Gaps: 106/951 - (11%)

  Fly    25 RLPKWLVPLSYRVDI-----VTRINQPYQPFGGTVVIDLRSERSTKRIVLNAHDLAIGKRRAVT- 83
            |||.|||||.|.:::     ..:::.|...|.|.|.|.:|...::.|::|  |...:..::...
Mouse    94 RLPPWLVPLHYDLELWPWLQPDKLSPPNLTFTGRVNITVRCTVASSRLLL--HSFLLNYKQVEVW 156

  Fly    84 --LSDKNGNS----VPVSSIQMDIKLSRLTVSLKRPLKVNVTYSMRVAFT-SVLRNDNTGFYSSN 141
              |:....|:    |.|..:.....:..:.:.|.:.|:....|.:...|: .||:....|.:.:.
Mouse   157 GPLAQDTRNATVGRVQVEKVWFAPDMQFVVLDLGQSLEPGSRYELSFHFSGQVLQVGLEGLFLNL 221

  Fly   142 YVDHNTTLTQWLAATQFEPNHAREAFPCFDDPIFRTPFKINLAHPYLYRALSNMPVQRTIRHASL 206
            |  |:....:.|.|||.||..||..|||||:|..:..|.|.:.|...|.||||||.........:
Mouse   222 Y--HDEDELRALVATQMEPTFARHVFPCFDEPALKATFNITVIHHPGYAALSNMPQLGQSERIDV 284

  Fly   207 KDYVW--TQFVESHPMQTYLVAFMISKFDRPGFTSSERSDCPISTWARPD--ALSQTEFANMVVA 267
            ....|  |.|..:..|.|||||.::...|.  .:.:||.. .|..|||.|  |....:||..:..
Mouse   285 NGSRWTVTTFHTTPRMPTYLVALVVCDLDH--ISRTERGK-EIRVWARKDDIASGYLDFAANITG 346

  Fly   268 PLLSFYEDLFNSTYRQKKIDLVALPDFTFKSKENWGLPAFAEESLLYDSQRSSIDDQQGVARAVA 332
            |:.||.|||||.:||..|.|:||||.|...:.|||||..|.|.|||.:.:....:.:..:...:|
Mouse   347 PIFSFLEDLFNISYRLPKTDIVALPIFASGAMENWGLLIFDESSLLLEPEDELTEKRAMILSIIA 411

  Fly   333 MMVVNQWFGNLVSVAWWHEIWLKNVFALYLSRFGVHSLRPEWDYQERHALQLYLSVLDYDAHVNT 397
            ..|.:|||||||:::||:.|||...||.|......:...|:..........:...:|..|..:.:
Mouse   412 HEVGHQWFGNLVTMSWWNNIWLNEGFASYFELELTNYFYPKVPMNMIFFFTVLHGILGEDHALES 476

  Fly   398 DLVTASV---PDESHIWAAYNEIGERKAAVLFEMLHRVMGEEAWLTALRRYLVVYANRTATSSDF 459
            ..|:.:|   .:.|.|...::....:|.|.:..||...:....::.||:.||..::...|...|.
Mouse   477 RAVSTAVENFTETSEINRLFDLYTYKKGACMAWMLASFLSPHLFINALKSYLETFSYSNAEQDDL 541

  Fly   460 WDLLQLQVDRNGRLGKGLNITRIMKCWLGQPGYPLVTVTRNYDHRTAIVSQQRFFITP-QFRNRW 523
            |..:|:.:...........:..||..|..:.|:|::||..:    |.:|.|:.|::.. :.:...
Mouse   542 WRHIQMAIGEQNVTHLPATVKGIMDSWTHRGGFPIITVNVS----TGVVKQEPFYLDKVENQTLL 602

  Fly   524 ARNPCWWVPLSYTCPSCQHSEIISFSRWLTCPTSKP---SSKSNTVLL-EKLEAEPTDWILFNVQ 584
            :.|..|.||:.                |:.....:|   ..|||.:.. .||....:||::.|..
Mouse   603 SHNSTWIVPIF----------------WMKNGIPQPLVWLDKSNMMFPGMKLSDSDSDWVILNFN 651

  Fly   585 HTAPFRVNYDLRNWQLLNKTL-ADPNKFRLIHRVNRAQLVDDLFSLAWSGDIEYDMALGILGYLE 648
            .|..:|||||...|:.|::.| .||   :.|..:||.|||.|.|:|..:..||.:.||.:..|:.
Mouse   652 VTGYYRVNYDELGWKKLSEQLEKDP---KAIPVINRLQLVSDAFALTKNNYIEIETALDLTKYIA 713

  Fly   649 HEDEFVVWVATEISFERIN-NVAKSNPNYLIFKTYMRLLLER------QFKRVISSDLTSSSGN- 705
            .|||.:||.  |:....|| .|.....||.::....:.||:|      .:..:|..::.|...|
Mouse   714 EEDEILVWF--EVLLNLINREVIYDVNNYALYPLLKKYLLKRFNSIWNTYSAIIRENVASLQDNY 776

  Fly   706 --MTHRPVIIRLACEYELPACVSLARREFMKGTPEKGGWMTIRERETVVCTAVKFGTEGDRDMVE 768
              :.....|...||...|..|:.|:|..|.|.|......:..:....|:|:||..|::.|.|.:.
Mouse   777 LSLFSLERIFETACWLGLEDCLQLSRELFKKWTAHPETAIPPQIENAVLCSAVALGSDKDWDFLF 841

  Fly   769 SMYKRSNFAAEKES----LLTALACSRNVFALQRVLIW--TFESSGVRKQNARRTFKAVVSNSMG 827
            ::|..:. ..|.||    |:.|::||::.:.|.|.:.:  |..||...:.|   ....|.::.:|
Mouse   842 NLYINTT-EEEDESRRRRLVHAMSCSKDPWILNRFMEYAITAVSSNFSETN---IIVVVATSEVG 902

  Fly   828 YRLAKKYVSVNMQNI-RNYCSNSTDKVVNLMTPLI-ECLSTPKELLYFSKFFKEILRDMNGSERL 890
            ..:||.::..|...: ..|..:..|.:|    |:: ..:||.:::.....||..:|.:
Mouse   903 RYIAKDFLMDNWVAVTERYGMDWLDALV----PVLGRTVSTDQQVTELQHFFSTVLEE------- 956

  Fly   891 IKILLERGNDNIHWQRTKFRPMLQAIRDIILWRSRAKRILK 931
                        | ||...:..|||::...|  ...|||.:
Mouse   957 ------------H-QRVVVQAKLQAMKTKNL--QNKKRIAR 982

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2111	NP_572644.1	M1_APN-Q_like	33..487	CDD:341064	133/473 (28%)
		ERAP1_C	578..897	CDD:463368	89/337 (26%)
Lvrn	NP_083284.1	M1_APN-Q_like	102..570	CDD:341064	134/474 (28%)
		ERAP1_C	645..964	CDD:463368	92/351 (26%)