Protein Alignment CG2111 and Aopep

DIOPT Version :10

• Sequence 1: NP_572644.1
• Gene: CG2111 / 31995
• FlyBaseID: FBgn0030223
• Length: 931
• Species: Drosophila melanogaster
• Sequence 2: NP_001276853.1
• Gene: Aopep / 72061
• MGIID: 1919311
• Length: 823
• Species: Mus musculus
• Alignment Length: 734
• Identity: 148/734 - (20%)
• Similarity: 247/734 - (33%)
• Gaps: 218/734 - (29%)

  Fly    36 RVDIVTRINQPYQPFGGTVVIDLRSERSTKRIVLNAHDLAIGKRRAVTLSDKNGNSVPVSSIQMD 100
            ::|..||.:|  .|..|.::||  |:..:.||                  .|.|.|.|...
Mouse   202 QLDCYTRCSQ--APGCGELLID--SDNWSLRI------------------RKTGTSTPADF---- 240

  Fly   101 IKLSRLTVSLKRPLKVNVTYSMR-----VAFTSVLRNDNTGFYSSNYVDHNTTLTQWLAATQFEP 160
                        |..:.:.|..:     ||:|:    |..|              :....|...|
Mouse   241 ------------PRAIRIWYKTKPEGQSVAWTT----DQNG--------------RPCVYTMGSP 275

  Fly   161 NHAREAFPCFDDPIFRTPFKINLAHPYLYRALSNMPV----QRTIRHASLKD-YV-WTQFVE-SH 218
            .:.|..|||.:.|:..:.::..:      ||.::..|    :.:.:...|:: |: |..:|. ..
Mouse   276 INNRALFPCQEPPVAMSTWQATV------RAAASFVVLMSGENSAKPTPLREGYMSWHYYVTMPM 334

  Fly   219 PMQTYLVAF-----MISKFDRPGFTSSERSDCPIS-------------------TWARPDALSQT 259
            |..|:.:|.     |..|...|....:|.| .|:|                   .:....|.||.
Mouse   335 PASTFAIAVGCWTEMKPKASPPDDLMTEHS-LPLSPSEADLRYDNTCNHMEYPCRFQSASAASQD 398

  Fly   260 EFANMVVAPL-----------------LSFYEDLFNSTYRQKKIDLVALPDFTFKSKENWGLPAF 307
            .....|.||:                 ||....:. .|:...::|::.:|       .|:.....
Mouse   399 IIPYRVFAPVCLEGACQEALLWLIPSCLSAAHSVL-GTHPFSRLDILIVP-------TNFPSLGM 455

  Fly   308 AEESLLYDSQRSSIDDQQGVARAVAMMVVNQWFGNLVSVAWWHEIWLKNVFALYLSRF---GVHS 369
            |...:::.||.:...........:...:.:.|||..:....|.|.||...||.:|...   ....
Mouse   456 ASPHIIFLSQSTLTGTSHLCGTRLCHEIAHSWFGLAIGARDWTEEWLSEGFATHLEDIFWAEAQQ 520

  Fly   370 LRPEWDYQER--------HALQLYL-------SVL----DYDAHVNTDLVTASV------PDESH 409
            |.|....:::        |.||..|       .||    :...||:..  .|||      |::..
Mouse   521 LPPHEALEQQELRACLRWHRLQDELRNSPEGMQVLRPNKEETGHVSAS--GASVVKHGLNPEKGF 583

  Fly   410 IWAAYNEIGERKAAVLFEMLHRVMGEEAWLTALRRYLVVYANRTATSSDFWDLLQLQVDRNGRLG 474
            :...|     .|...|...|.|.:||:.:...||:::.::..:...|.||..:|...:..|.||
Mouse   584 MQVHY-----LKGYFLLRFLTRTLGEKIYFPFLRKFVHLFHGQLILSQDFLQMLLENIPENKRL- 642

  Fly   475 KGLNITRIMKCWLGQPGYP--LVTVTRNYDHRTAIVSQQ---------RFFITPQFRNRWARNPC 528
             ||::..|::.||...|.|  |....:..|...:.:::|         |....|:.|.|..|.
Mouse   643 -GLSVENIVRDWLECSGIPKALQEERKAEDCSPSRLARQVGSEVAKWIRVNRRPRKRKRGKRE-- 704

  Fly   529 WWVPLSYTCPSCQHSEIISFSRW-LTCPTSKPSS---KSNTVLLEKLEAEPTDWILFNVQHTAPF 589
              |......|    .:|:....| |...|..|.:   ...|..|.:.:||        |:|
Mouse   705 --VAFEKLSP----DQIVLLLEWLLEQKTLSPQTLHCLQQTYHLPEQDAE--------VRH---- 751

  Fly   590 RVNYDLRNW-QLLNKTLADPNKF-RLIHRVNRAQLVDDLFSLAWSGD--IEYDMALGILGY---- 646
                   .| :|:.|     :|: :..::|.|..|.|....:...|:  :..|..|..|.:
Mouse   752 -------RWCELVIK-----HKYTKAYNQVERFLLEDQAMGIYLYGELMVSEDARLQQLAHRCFE 804

  Fly   647 --LEHEDEFVVWVATEISF 663
              .||.|.....|.||:.|
Mouse   805 LVKEHMDRASAQVVTEMLF 823

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2111	NP_572644.1	M1_APN-Q_like	33..487	CDD:341064	104/531 (20%)
		ERAP1_C	578..897	CDD:463368	21/96 (22%)
Aopep	NP_001276853.1	GluZincin	<244..641	CDD:472708	83/436 (19%)
		Nucleolar localization signal. /evidence=ECO:0000269|PubMed:17803194	693..703		3/9 (33%)
		Leuk-A4-hydro_C	710..822	CDD:462686	30/139 (22%)