Protein Alignment CG2111 and anpeplb

DIOPT Version :10

• Sequence 1: NP_572644.1
• Gene: CG2111 / 31995
• FlyBaseID: FBgn0030223
• Length: 931
• Species: Drosophila melanogaster
• Sequence 2: NP_001038326.1
• Gene: anpeplb / 558452
• ZFINID: ZDB-GENE-030131-4781
• Length: 946
• Species: Danio rerio
• Alignment Length: 969
• Identity: 260/969 - (26%)
• Similarity: 437/969 - (45%)
• Gaps: 113/969 - (11%)

  Fly     8 ILTALFFHLEA--NKTAVG-----------------RLPKWLVPLSYRVDIVTRINQPY------ 47
            ::.|:||.::.  ||....                 |||..|:|.||.|.:     |||
Zfish    27 VVMAVFFQIQVGNNKPTPPPRPILPTPLPTDLPESLRLPDSLIPESYNVFL-----QPYLYAAIT 86

  Fly    48 -------QPFGGTVVIDLRSERSTKRIVLNAHDL---AIGKRRAVTLSDKNGNSVPVSSIQM-DI 101
                   ..|.|...:.:...:::.|:.|:.|::   |:..|:    ||.| ..:|:...|: ..
Zfish    87 NNYTEQSYLFTGNSTVRVNCTKTSSRVFLHVHNINVTAVEVRK----SDTN-EKLPLKGYQIFKN 146

  Fly   102 KLSRLTVSLKRPLKVNVTYSMRVAFTSVLRNDNTGFYSSNYVDHNT---TLTQWLAATQFEPNHA 163
            :.:.|.:.|:..:|.|.||.:...|...|..|.||||:|.|....|   ...::||.:..:|..|
Zfish   147 ETNFLDIHLEVAIKENGTYDIFTEFEGELLEDLTGFYASRYTGKGTDDEDEERFLATSLLQPTDA 211

  Fly   164 REAFPCFDDPIFRTPFKINLAHPYLYRALSNMPVQ-RTIRHASLKDYVWTQFVESHPMQTYLVAF 227
            |..|||||:|..:..|.|.:.|....||.||.... |||: .:..|::.|.|..:..|.:||:.|
Zfish   212 RTVFPCFDEPAMKAVFTITIIHRPEIRARSNEDGDPRTIQ-INGTDWIRTTFKPTKKMSSYLLGF 275

  Fly   228 MISKFDRPGFT-SSERSDCPISTWARPDAL--SQTEFANMVVAPLLSFYEDLFNSTYRQKKIDLV 289
            :|  :|...|: .|:.:...|....|.:|:  ...::|......:||.||::|...|...|||.:
Zfish   276 II--YDTHTFSYVSKGTRTKIHVHGRSEAIDAGHADYALETTETILSHYENIFGLRYPMSKIDQI 338

  Fly   290 ALPDFTFKSKENWGLPAFAEESLLYDSQRSSIDDQQGVARAVAMMVVNQWFGNLVSVAWWHEIWL 354
            |||||..::.||||..::.|..||||.:.:|..|::.|...:|..:.:|||||||:::||:::||
Zfish   339 ALPDFGVRAMENWGFISYQESGLLYDKETASTFDEEQVTTLIAHELAHQWFGNLVTMSWWNDLWL 403

  Fly   355 KNVFALYLSRFGVHSLRPEWDYQERHALQLYLSVLDYDAHVNT----DLVTASVPDESHIWAAYN 415
            |..||.|:|..||.::  .||.::...|:...:....|: :||    .:....|...|.|...::
Zfish   404 KEGFATYMSYKGVEAV--GWDLKDLIVLREIQTAFQMDS-LNTSHPLSMNAYDVQTSSQISELFD 465

  Fly   416 EIGERKAAVLFEMLHRVMGEEAWLTALRRYLVVYANRTATSSDFWDLLQLQVDRNGRLGKGLNIT 480
            :|...|.|.:..||...|||..::..::.||..:........|.|:.|.:...        :.:.
Zfish   466 DITYSKGAAVLRMLATRMGENEFMKGVKMYLSKFQFENTVPKDLWECLNMDTH--------IKVD 522

  Fly   481 RIMKCWLGQPGYPLVTVTRNYDHRTAIVSQQRFFITPQFRNRWARNPCWWVPLSYTCPSCQHSEI 545
            ..||.|..:.|||::|:..:    |...||::|.:    :.....:..|.:|:.|........|
Zfish   523 EFMKTWTEEVGYPVLTIITD----TGDTSQEQFLL----KKEGGHDSLWHIPIKYMTLKAGVKE- 578

  Fly   546 ISFSRWLTCPTSKPSSKSNTVLLEKLEAEPTDWILFNVQHTAPFRVNYDLRNWQLLNKTLADPNK 610
              |..:.|.....|        :...:....:|:|.|:..|..:|||||..||..|...|  ...
Zfish   579 --FPNFFTDKGPDP--------IPDFKIGKDNWLLANINCTGFYRVNYDEENWNRLTAQL--QKN 631

  Fly   611 FRLIHRVNRAQLVDDLFSLAWSGDIEYDMALGILGYLEHEDEFVVWVATEISFERINNVAKSNPN 675
            .|:|..:||.||:||.|:||.:..:...:||.:..||.::.|::.|.:...:.:....:...:..
Zfish   632 HRIIPLINRGQLIDDAFNLARAHRLNVTIALNLTKYLINDLEYIPWESALKNLDFFTLMFDRSEV 696

  Fly   676 YLIFKTYMRLLL--------ERQFKRVISSDLTSSSGNMTHRPVIIRLACEYELPACVSLARREF 732
            |.....|:|.|:        |......|..:..:...|..:   .|.:||...||.|:::|:..|
Zfish   697 YGPIMKYLRNLVTPLYEEYEEYTINGTIPIEKYTDQCNQVN---AITVACSNGLPECITMAKDLF 758

  Fly   733 MKGTPEKGGWMTIRE--RETVVCTAVKFGTEGDRDMVESMYKRSNFAAEKESLLTALACSRNVFA 795
               :..|.|...|..  |..|.|:||..|.|.|.:.|...|:::..||||:.|..||:|::.::.
Zfish   759 ---SDYKNGSNPIHPNLRRAVYCSAVASGDEDDWEYVWEEYQKATVAAEKDKLRYALSCTKEIWL 820

  Fly   796 LQRVLIWTFESSGVRKQNARRTFKAVVSNSMGYRLAKKYVSVNMQNIRNYCSNSTDKVVNLMTPL 860
            |.|.|.:|.|.|.:||.:...|...:..|..|..||..::..:...|..........:.:|:..:
Zfish   821 LNRYLQYTLEPSKIRKMDMVSTISYIAQNVAGQPLAWDFIRGHWSYITQEYGAGIISLGSLLDVV 885

  Fly   861 IECLSTPKELLYFSKFFKEILRDMNG-SERLIKILLERGNDNIHWQRTKFRPMLQAIRD 918
            .:..||..||....:..:|.::|... :.|.::.::||...||.|.:..    .|.::|
Zfish   886 TKRFSTEVELEELKQLQREQIQDDKWIAARALEQVIERTAANIIWVKEN----KQVVKD 940

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2111	NP_572644.1	M1_APN-Q_like	33..487	CDD:341064	139/481 (29%)
		ERAP1_C	578..897	CDD:463368	88/329 (27%)
anpeplb	NP_001038326.1	M1_APN-Q_like	71..530	CDD:341064	140/482 (29%)
		ERAP1_C	601..926	CDD:463368	90/332 (27%)