Protein Alignment CG2111 and anpepla

DIOPT Version :10

• Sequence 1: NP_572644.1
• Gene: CG2111 / 31995
• FlyBaseID: FBgn0030223
• Length: 931
• Species: Drosophila melanogaster
• Sequence 2: XP_001922987.2
• Gene: anpepla / 555317
• ZFINID: ZDB-GENE-141215-4
• Length: 956
• Species: Danio rerio
• Alignment Length: 932
• Identity: 259/932 - (27%)
• Similarity: 426/932 - (45%)
• Gaps: 113/932 - (12%)

  Fly    25 RLPKWLVPLSYRVDIVTRINQP---YQPFGGTVVIDLRSERSTKRIVLNAHDL---AIGKRRAVT 83
            |||..|:|..|.:.:..|:.:.   ...|.|...:.....:.|..|::::.:|   ...::....
Zfish    69 RLPDTLLPEYYNITLWPRLTKDDLGMYIFTGKSGVAFLCVKETDLILIHSSNLNYSLTAEKHHAE 133

  Fly    84 LSDKNGNSVPV-SSIQMDIKLSRLTVSLKRPLKVNVTYSMRVAFTSVLRNDNTGFYSSNYVDHNT 147
            |....|...|| .......:...:.:.|:..|:|..:|.:...|...|.:|..|||.|.||::.
Zfish   134 LMGLGGTRAPVILKTWFQDQTEFMVIQLRENLQVGKSYWLYTEFQGELADDLGGFYRSEYVENG- 197

  Fly   148 TLTQWLAATQFEPNHAREAFPCFDDPIFRTPFKINLAHPYLYRALSNMPVQRTIRHASLKD--YV 210
             :.:.:|.||.:|..||.||||||:|..:..|.:.|.||....||:| .::....:.::::  .:
Zfish   198 -VEKVVATTQMQPTAARTAFPCFDEPSMKAVFHLTLIHPPGTVALAN-GMETGTENITIENQQVL 260

  Fly   211 WTQFVESHPMQTYLVAFMISKFDRPGFTSSERSDCPIST-------WARPDALSQTE--FANMVV 266
            .|:|..:..|.|||:||:||:|  |...|      |:..       |.|.:|:...|  :|..|.
Zfish   261 QTRFEPTEKMSTYLLAFVISEF--PSIQS------PLGANKILVRIWGRREAIENGEGDYALNVT 317

  Fly   267 APLLSFYEDLFNSTYRQKKIDLVALPDFTFKSKENWGLPAFAEESLLYDSQRSSIDDQQGVARAV 331
            .|:|.:.|..:|:||...|.|.:|||||:..:.|||||..:.|..|.|:.:.||.:|::||...:
Zfish   318 FPVLKYLESYYNTTYPLSKSDQIALPDFSAGAMENWGLVTYRETFLFYEPKVSSHEDKEGVITVI 382

  Fly   332 AMMVVNQWFGNLVSVAWWHEIWLKNVFALYLSRFGVHSLRPEWDYQERHALQLYLSVLDYDAHVN 396
            :..:.:.||||||::.||:::||...||.|:|........|.|:.:|...||........||.|:
Zfish   383 SHELAHMWFGNLVTMRWWNDLWLNEGFASYVSYLAADYAEPTWNIKELMVLQQVYRAFTVDALVS 447

  Fly   397 TDLVTA---SVPDESHIWAAYNEIGERKAAVLFEMLHRVMGEEAWLTALRRYLVVYANRTATSSD 458
            :..:::   :|.....|...::.:...|.|.:..||...:.|..:...|..||..:|......:|
Zfish   448 SHPLSSREDAVNTPQQIEELFDAVTYSKGAAVLRMLSEFLSESVFAKGLHNYLQEHAYSNTVYTD 512

  Fly   459 FWDLLQLQVDRNGRLGKGLNITRIMKCWLGQPGYPLVTVTRNYDHRTAIVSQQRFFITPQFRNRW 523
            .|..||...|.:|.:....:|..||..|:.|.|:|:||:    |..|..:|||.|.|.|:   ..
Zfish   513 LWKKLQEVADSDGNVHLPASIEEIMNRWILQAGFPVVTI----DTHTGSISQQHFLIDPE---AV 570

  Fly   524 ARNPC-----WWVPLSYTCPS---CQHSEIISFSRWLTCPTSKPSSKSNTVLLEKLEAEPTDWIL 580
            ...|.     |:||:::....   .||        ||.       :||.:..|.|.|   |:|||
Zfish   571 VNKPSDYNYEWFVPITWMKNGRNMGQH--------WLL-------NKSTSYELMKTE---TNWIL 617

  Fly   581 FNVQHTAPFRVNYDLRNWQLLNKTLADPNKFRLIHRVNRAQLVDDLFSLAWSGDIEYDMALGILG 645
            .|:..|..:|||||.:||:.|.|.|...:  :.|..:||.|::||.|:||.:..:...|||....
Zfish   618 ANLNVTGYYRVNYDSQNWERLIKQLTSDH--QAIPVLNRGQIIDDAFTLARAKILNITMALRTTQ 680

  Fly   646 YLEHEDEFVVWVAT----EISFERINNVAKSNPNYLIFKTYMRLLLERQFK--RVISSDLTSSSG 704
            ||.:|.|::.|.:.    |..|...:......|    .:.|:|..:|..|.  :||:|
Zfish   681 YLSNEKEYIPWESAIRNLEYFFLMFDRTEVRGP----LEAYLRRKVEPLFHYFKVITS------- 734

  Fly   705 NMTHRPV----------IIRLACEYELPAC---VSLARREFMKG---TPEKGGWMTIRERETVVC 753
            |.|.:|.          .|.:||:..:.||   .|:..|::||.   .|......|:     |.|
Zfish   735 NWTRKPTRHMDQYNQLNAITMACKTRVKACSELTSMWYRQWMKDPNVNPVPSDLKTV-----VYC 794

  Fly   754 TAVKFGTEGDRDMVESMYKRSNFAAEKESLLTALACSRNVFALQRVLIWTFESSGVRKQNARRTF 818
            .|:..|...:.|...:|:|.|..|||.|.|:..|:|::..:.|.|.|.:..:.:.:|||:.....
Zfish   795 NAIAAGGVEEWDFGWAMFKNSTVAAEAEKLMYGLSCTKEPWLLNRYLHYAIDPNLIRKQDVTYPI 859

  Fly   819 KAVVSNSMGYRLAKKYVSVNMQNIRNYCSNSTDKVVNLMTPLIECLSTPKELLYFSKFFKEILRD 883
            ..:.||.:|..||..:.....|.:       |.:...|:..:::..||..:|....:|.:|:...
Zfish   860 VYIASNVIGQPLAWDFFRAKWQLM-------TTEFRVLILGIVKTFSTEFQLQQLQRFQEEVAES 917

  Fly   884 -MNGSERLIKILLERGNDNIHW 904
             ::.....|:..:|:...|:.|
Zfish   918 GVSLGTHAIEQAIEQTKANVKW 939

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2111	NP_572644.1	M1_APN-Q_like	33..487	CDD:341064	132/474 (28%)
		ERAP1_C	578..897	CDD:463368	91/341 (27%)
anpepla	XP_001922987.2	M1_APN-Q_like	79..542	CDD:341064	133/473 (28%)
		ERAP1_C	615..935	CDD:463368	92/344 (27%)