Protein Alignment CG2111 and Lvrn

DIOPT Version :10

• Sequence 1: NP_572644.1
• Gene: CG2111 / 31995
• FlyBaseID: FBgn0030223
• Length: 931
• Species: Drosophila melanogaster
• Sequence 2: XP_038953135.1
• Gene: Lvrn / 502160
• RGDID: 1562779
• Length: 987
• Species: Rattus norvegicus
• Alignment Length: 924
• Identity: 258/924 - (27%)
• Similarity: 411/924 - (44%)
• Gaps: 130/924 - (14%)

  Fly    25 RLPKWLVPLSYRVDIVTR-----INQPYQPFGGTVVIDLRSERSTKRIVLNAH-----------D 73
            |||.|||||.|.:::..|     ::.|...|.|.|.|.:|...:|..::|::.           .
  Rat    94 RLPPWLVPLHYDLELWPRLQPDNLSTPSLTFTGRVNITVRCTVATSTLLLHSFFLNYKQVEVWGP 158

  Fly    74 LAIGKRRAVTLSDKNGNSVPVSSIQMDIKLSRLTVSLKRPLKVNVTYSMRVAFT-SVLRNDNTGF 137
            ||...|.|..      ..||:.::...:.:..:.:.|.:.|....:|.:...|: .||:..:.|.
  Rat   159 LAPDTRNATV------GRVPLENVWFALDMQYVVLDLGQSLDPGSSYELNFDFSGQVLQEGSEGL 217

  Fly   138 YSSNYVDHNTTLTQWLAATQFEPNHAREAFPCFDDPIFRTPFKINLAHPYLYRALSNMPVQRTIR 202
            :.:.|.|.:.  .:.|.|||.||..||..|||||:|..:..|.|.:.|...|.||||||......
  Rat   218 FLNLYTDEDQ--LRALIATQMEPTFARHVFPCFDEPALKATFNITIIHHPGYVALSNMPQLGQSH 280

  Fly   203 HASLKDYVW--TQFVESHPMQTYLVAFMISKFDRPGFTSSERSDCPISTWARPDALSQ--TEFAN 263
            ...:....|  |.|..:..|.|||||.:|..||   :.|.......|..|||.|.::.  .:||.
  Rat   281 RIDVNGSRWTVTSFHTTPRMPTYLVALVICDFD---YVSRTERGKEIRVWARKDDIADGYLDFAA 342

  Fly   264 MVVAPLLSFYEDLFNSTYRQKKIDLVALPDFTFKSKENWGLPAFAEESLLYDSQRSSIDDQQGVA 328
            ....|:.||.|||||.:|...|.|::|||.|...:.|||||..| :.|||.:     :||.....
  Rat   343 NHTGPVFSFLEDLFNISYPLPKTDIIALPTFVNGAMENWGLMIF-DASLLLE-----LDDDLPEK 401

  Fly   329 RAVAMMVV-----NQWFGNLVSVAWWHEIWLKNVFALYLSRFGVHSLRPEWDYQERHALQLYLSV 388
            ||:.:.::     :|||||||:::||:.|||...||.|......:...|:........|.:...:
  Rat   402 RAMILSILSHEVGHQWFGNLVTMSWWNNIWLNEGFASYFEVGLTNYFYPKVPRNMIFFLTVLHDI 466

  Fly   389 LDYDAHVNTDLVTASVPDESHIWAAYNEIGE-------RKAAVLFEMLHRVMGEEAWLTALRRYL 446
            |:.|..:.:..|  |.|.|:  :....||..       :|.|.:..||...:.:..::.||:.||
  Rat   467 LEDDHSLESRAV--STPVEN--FTETREINRLFDIYTYKKGACMAWMLAGFLSQHLFINALKSYL 527

  Fly   447 VVYANRTATSSDFWDLLQLQVDRNGRLGKGLNITRIMKCWLGQPGYPLVTVTRNYDHRTAIVSQQ 511
            ..::...|...|.|..:|:.:|....:.....:.|||..|..|.|:|::|:..:    |.:|.|:
  Rat   528 ETFSYSNAEQDDLWRHIQMAIDEQSIIHLPATVKRIMDSWTHQSGFPVITLNAS----TGVVKQE 588

  Fly   512 RFFI------TPQFRNRWARNPCWWVPLSYTCPSCQHSEIISFSRWLTCPTSKPSSKSNTVLL-E 569
            .|::      |....|.|. .|.:|:....|.|..          ||        .||:.:.. .
  Rat   589 PFYLERVENQTLLSHNTWI-VPIFWMKNGITQPLV----------WL--------DKSSMIFPGM 634

  Fly   570 KLEAEPTDWILFNVQHTAPFRVNYDLRNWQLLNKTL-ADPNKFRLIHRVNRAQLVDDLFSLAWSG 633
            ||....:||::.|...|..:|||||...|:.||:.| .||   :.|..:||.|||.|.|:|:.:.
  Rat   635 KLSDSDSDWVILNFNVTGYYRVNYDKLGWKKLNQQLEKDP---KAIPVINRLQLVSDAFALSKNN 696

  Fly   634 DIEYDMALGILGYLEHEDEFVVWVATEISFERIN-NVAKSNPNYLIFKTYMRLLLERQ------F 691
            .||.:.||.:..|:..|||.:||.  |:....|| .|.....||.::....:..|:|.      :
  Rat   697 YIEIETALDLTKYIAKEDEILVWF--EVLVNLINREVVYDVKNYYLYPLLKKYFLKRLNSIWTIY 759

  Fly   692 KRVISSDLTSSSGN-MTHRPV--IIRLACEYELPACVSLARREFMKGTPEKGGWMTIRE------ 747
            ..:|..::.|...| ::..|:  ....||...|..|:.|:|..|.|       ||...|
  Rat   760 SAIIRENMASLQDNFLSLLPLKKFFETACWLGLEDCLQLSRELFRK-------WMAHPETAIPPQ 817

  Fly   748 -RETVVCTAVKFGTEGDRDMVESMYKRSNFAAEKES---LLTALACSRNVFALQRVL---IWTFE 805
             .:.|:|.|:..|:..|.|.:.::|  .|...|:|.   |:.|:.||::...|.|.:   |..|.
  Rat   818 IEKVVLCNAIALGSNKDWDFLFNLY--INKTEEQEDLFHLVHAMGCSKDPRTLNRFMEYDITVFP 880

  Fly   806 SSGVRKQNARRTFKAVVSNSMGYRLAKKYVSVNMQNI-RNYCSNSTDKVVNLMTPLIECLSTPKE 869
            |    :.|.....:.|..:.:|..:||.::..|...: ..|...|.:.:|::   |...:||.::
  Rat   881 S----RFNETNLIEVVAESEVGRYVAKDFLINNWVAVYERYGPQSLNTLVSI---LGRTVSTDQQ 938

  Fly   870 LLYFSKFFKEILRD 883
            ::...:|...:|.:
  Rat   939 VMELQQFLSTVLEE 952

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2111	NP_572644.1	M1_APN-Q_like	33..487	CDD:341064	139/486 (29%)
		ERAP1_C	578..897	CDD:463368	89/331 (27%)
Lvrn	XP_038953135.1	M1_APN-Q_like	102..569	CDD:341064	140/487 (29%)
		ERAP1_C	643..948	CDD:463368	88/325 (27%)