Protein Alignment CG2111 and CG46339

DIOPT Version :10

• Sequence 1: NP_572644.1
• Gene: CG2111 / 31995
• FlyBaseID: FBgn0030223
• Length: 931
• Species: Drosophila melanogaster
• Sequence 2: NP_001263001.1
• Gene: CG46339 / 44359
• FlyBaseID: FBgn0285963
• Length: 1194
• Species: Drosophila melanogaster
• Alignment Length: 945
• Identity: 259/945 - (27%)
• Similarity: 446/945 - (47%)
• Gaps: 110/945 - (11%)

  Fly    32 PLSYRV----DIVTRINQPYQPFGGTVVIDLRSE----RSTKRIVLNAHDLAIGKRRAV-TLSDK 87
            ||.|.:    .:.|.|:      .|::.|::..:    .|.:.|||:.|:::|...|.: .|:|.
  Fly   296 PLHYSLLIEPSVATSIS------NGSLTIEIERDVSKVTSWEPIVLDVHNVSISNVRVIRALADG 354

  Fly    88 NGNSVPVSSIQMD-----------IKLSRLTVSLKRPLKVNVTYSMRVAFTSVLRNDNTGFYSSN 141
            ..|:.....:..|           |.||: |::::..|:|    .:.:.|.|.:.:...|.|.::
  Fly   355 ASNASEEQDLDFDSDYGEDNATFVINLSK-TLAVETQLRV----LLSLDFVSQVTDTLQGIYKTS 414

  Fly   142 YVDHNTTLTQWLAATQFEPNHAREAFPCFDDPIFRTPFKINLAHPYLYR-ALSNMPV--QRTIRH 203
            |.:.:|...:|:.:|||.|..||.||||||.|..:..|.|::..|..:: ||||||.  .|..|.
  Fly   415 YTNPDTKNEEWMISTQFSPVDARRAFPCFDRPDMKANFSISIVRPMQFKMALSNMPKSGSRRFRR 479

  Fly   204 ASLKDYVWTQFVESHPMQTYLVAFMISKFDRPGFTSSERSDCP-ISTWARPDALSQTEFANMVVA 267
            ..::|    .|..:..|.||||||::|........|.:....| :..|.||..:..|.:|..:|.
  Fly   480 GFIRD----DFETTPKMPTYLVAFIVSNMVDSRLASQDSGLTPRVEIWTRPQFVGMTHYAYKMVR 540

  Fly   268 PLLSFYEDLFNSTYRQKKIDLVALPDFTFKSKENWGLPAFAEESLLY--DSQ-RSSIDDQQGVAR 329
            ..|.:|||.|....:..|||||::|||.|.:.|||||..|.:.:||.  |.| .||.:..|.||.
  Fly   541 KFLPYYEDFFGIKNKLPKIDLVSVPDFGFAAMENWGLITFRDSALLVPEDLQLASSSEHMQVVAG 605

  Fly   330 AVAMMVVNQWFGNLVSVAWWHEIWLKNVFALYLSRFGVHSLRPEWDYQERHALQLYLSVLDYDAH 394
            .:|..:.:|||||||:..||.::|||..||.|:|...:....||:...:...:..:...:::||.
  Fly   606 IIAHELAHQWFGNLVTPKWWDDLWLKEGFACYMSYKALEHAHPEFQSMDTLTMLEFKESMEHDAD 670

  Fly   395 VNTDLVTASVPDESHIWAAYNEIGERKAAVLFEMLHRVMGEEAWLTALRRYLVVYANRTATSSDF 459
            ..:..::..|...:.:...::.|...|..:|..||:.::|:.|:.:|.|..|..:|.......|.
  Fly   671 NTSHAISFDVRSTNDVRRIFDPISYSKGTILLRMLNSIVGDVAFRSATRDLLKKFAYGNMDRDDL 735

  Fly   460 WDLLQLQVDRNGRLGKGLNITRIMKCWLGQPGYPLVTVTRNYDHRTA-IVSQQRFFITPQFRNRW 523
            |.:|.......|.|.|.|::.:||..|:.|||||:|.|.|    |.| :|.:|..::.|.  ...
  Fly   736 WAMLTRHGHEQGTLPKDLSVKQIMDSWITQPGYPVVNVER----RGADLVLRQERYLLPS--KNT 794

  Fly   524 ARNPCWWVPLSYTCPSCQHSEIISFSRWLTCPTSKP---------SSKSNTVLLEKLEAEPTDWI 579
            |....|::|:::.....:..:.|. :.|:.....:.         ||.|:.|            |
  Fly   795 ADQSTWFIPITFETDELRKGDNIP-THWMRSEDEEELIVGNVFAHSSNSDNV------------I 846

  Fly   580 LFNVQHTAPFRVNYDLRNWQLLNKTLADPNKFRLIHRVNRAQLVDDLFSLAWSGDIEYDMALGIL 644
            ..|:.....:|||||:.:|..|.|      .|..:.|:.||||:||...|:.:..:.||:.|..|
  Fly   847 YLNLNRQGYYRVNYDMTSWLALKK------NFSTLPRITRAQLLDDALHLSQAEYLTYDIPLTFL 905

  Fly   645 GYL-EHEDEFVVWVATEISFERINNVAKSNPNYLIFKTYMRLLLERQFKRV-ISSDLTSSSGNMT 707
            ..| :..|:.::|:|.:.....:....|..|.|..|:.:|:.::...|... :......|...:.
  Fly   906 MELFDAVDDELLWIAAKPGLNYLIYNLKREPAYETFRAFMKFIVRPAFDHYGLHEPDNESHLQLK 970

  Fly   708 HRPVIIRLACEYELPACVSLAR---REFM---KGTPEKGGWMTIRERETVVCTAVKFGTEGDRDM 766
            ||.::...||::....|...|:   ||:|   |..|.|....::     :.||::..|:..:...
  Fly   971 HRALVAYFACKFNYDRCTQKAQMKFREWMRDPKNNPIKPNLKSV-----IYCTSLAEGSSPEWYF 1030

  Fly   767 VESMYKRSNFAAEKESLLTALACSRNVFALQRVLIWTFE-SSGVRKQNARRTFKAVVSNSMGYRL 830
            ....||.:..|:|||.:||:|.|:...:.|.:.|..|.. :||:.||:....|:||.||::|:.:
  Fly  1031 AYKQYKTTTSASEKEEILTSLGCTTKPWLLSKYLNMTINPTSGILKQDGALAFRAVASNAIGHEI 1095

  Fly   831 AKKYVSVNMQNIRNYCSNSTDKVVNLMTPLIECLSTPKELLYFSK-FFKEILRD---------MN 885
            |..::..|::.|..|..:.    .:.::.:|:.|:     :|.:| :.|..|.|         ::
  Fly  1096 AFDFLQGNIKEIVEYYGDG----FSTLSEMIKSLT-----IYMNKDYHKHQLLDLAATCRKLGLH 1151

  Fly   886 GSERLIKILLERGNDNIHWQRTKFRPMLQAIRDII 920
            ..|..|::.||:.|:||:|:...:..:...:..|:
  Fly  1152 AVESAIELALEQVNNNIYWRSHSYHSLKNFLEGIV 1186

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2111	NP_572644.1	M1_APN-Q_like	33..487	CDD:341064	143/480 (30%)
		ERAP1_C	578..897	CDD:463368	86/337 (26%)
CG46339	NP_001263001.1	M1_APN-Q_like	297..764	CDD:341064	144/481 (30%)
		ERAP1_C	846..1126	CDD:463368	77/294 (26%)